Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We had a case of malignant lymphoma of the colon with two lesions, one in the transverse colon and the other in the ascending colon. The tumor of the transverse colon was resected, but that of the ascending colon was unresectable. Chemotherapy was performed through the catheter with reservoir via the iliac artery into the right colic artery. Three months later, the tumor disappeared completely, and the ascending colon was resected. On histopathological examination, there was no lymphoma cell in the ascending colon. Chemotherapy by a transarterial catheter with reservoir is a new method of treatment against malignant lymphoma.
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PMID:[A case of chemotherapy by the transarterial catheter with reservoir against malignant lymphoma of the colon]. 278 96

The incidence of metastases from gastric adenocarcinoma to various regional lymph node stations was studied after meticulous node dissection and correlated to survival in 1931 resected patients. The incidence of metastases increased with deeper tumor invasion into the stomach wall. Deposits were most common in some perigastric node stations, and their distribution was clearly related to the location of the tumor. Some nonperigastric node stations also were frequently involved, e.g., those around the left gastric artery or in the splenic hilum, and may be considered primary draining nodes. Skip metastases to distant nodes were found in a few per cent of perigastric node-negative patients. Deposits in nodes around the middle colic artery, but not in any other upper abdominal node stations, were incompatible with 5-year survival rates. The analysis favors a so-called R2 or more extensive resection for cancers invading beyond the submucosa.
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PMID:Lymph node metastases of gastric cancer. General pattern in 1931 patients. 281 28

The clinical signs, medical and surgical management, and pathological findings are described for a ganglioneuroma, an atypical intestinal tumor, that caused colic because of small intestinal obturation.
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PMID:Ganglioneuroma as a cause of small intestinal obstruction in the horse: a case report. 292 77

Transitional cell carcinoma is associated with analgesic nephropathy. Detection of this neoplasm may be delayed because hematuria and colic are the usual symptoms in both conditions. Plain film findings of displacement of the renal calcifications occurring in analgesic nephropathy may be the first sign of transitional cell carcinoma.
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PMID:Displaced calcium as a sign of transitional cell carcinoma in analgesic nephropathy. 294 31

We report a case of gastrointestinal lymphomatous polyposis revealed by a rectal tumor. Numerous polypoid lesions, 5 to 20 mm in diameter, were found at various levels of the gastrointestinal tract. Microscopic examination of gastric, duodenal, colic and rectal specimens led to the diagnosis of small cleaved-cell type lymphoma. The immunohistochemical study showed a monotypic surface staining of the lymphomatous cells with anti-IgM, IgD, kappa, C3b, and CD5 antibodies. This type of lymphoma is rare and presents as multifocal polyposis of the gastrointestinal tract. Only histologic and immunohistologic studies can establish diagnosis. Gastrointestinal lymphomatous polyposis is classified as a low-grade malignant lymphoma, with frequent nodal, hepatosplenic, bone marrow, and blood involvement. Chemotherapy is the appropriate treatment.
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PMID:[Digestive lymphomatous polyposis: study of a case diagnosed by rectal biopsy]. 337 98

Between 1971 and 1986, 52 villous tumors of the rectum were surgically treated, which represents 8 p. cent of recto-colic tumors. The mean patient's age was 65 years. There were sessile tumors in 69 p. cent of the cases, pedunculated in 17 p. cent and flowing tumors in 12 p. cent. The mean tumor size was 3 cm. They were associated with a colon cancer in 15 p. cent of the cases, and a polyadenoma in 10 p. cent. They were located on the rectum from 0 to 6 cm in half of the cases. In one case, the tumor extended to the entire rectum. These tumors were treated in 37 cases by local excision and in 15 cases by wide excision. Three patients were re-operated upon for an extended excision. The malignant potential of the tumors was 30 p. cent including 10 p. cent of invasive malignancy. There were no surgical fatalities, but 6 p. cent of medical fatalities. There were 20 p. cent complications related to the surgical technique. 10 patients were lost to follow-up. In 42 villous tumors followed with a mean survival of 6.5 years, there were 12 recurrences: 9 underwent endoscopic excisions and in 3 cases a wide resection: Babcock, Duhamel, amputation. The various technique of tumor resection as well as operative indications of variable difficulty are presented. It seems, at present, that a total resection of the rectum with colo-anal anastomosis represents the best treatment for large flowing villous tumors extending almost though the entire rectum.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Surgical treatment of villous tumors of the rectum]. 342 40

Mucocele of the appendix was first described and named "Hydrops processus vermiformis" by Rokitansky in 1866. Intussusception of a appendiceal mucocele is very rare and we have been able to find only 14 previously reported cases. We present two cases with preoperative ultrasonography which is valuable for its diagnosis. Case 1: A 5-year-old male was admitted to Kahoku Hospital because of right lateral colic abdominal pain and tumor. Ba-enema examination revealed intussusception to the colon and ultrasonography showed the cystic mass of the appendix. Case 2: A 51-year-old female was admitted because of right lower abdominal pain. Ultrasonography was helpful showing the cystic tumor at the base of the appendix. Recent reports say that ultrasonography is valuable examination for its diagnosis. Also in our two cases preoperative ultrasonography was performed and gave us valid information for its qualitative diagnosis.
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PMID:[Two cases of intussusception of appendiceal mucocele: diagnostic value of preoperative ultrasonography]. 352 15

After curative surgery for rectal or sigmoid cancer, loco-regional recurrence occurs in about 30% of the patients. Among them, one third presents no other tumor localization and a new curative surgical excision may, therefore be considered. A review of the literature shows that in these repeated procedures, the only good results, carcinologically, are observed when the original procedure consisted in a recto-colic anastomosis. Re-operations after abdomino-perineal resections have, until now, resulted in carcinologic failures. The location of the pelvic recurrence, after procedures which preserve the anal sphincter function, may be at the level of the anastomosis or most of the time around the anastomosis. If endoscopy is an easy mean of surveillance of the anastomosis, the screening of peri-anastomotic recurrences presents more of a problem. It seems necessary to use, in addition to rectal examination, other techniques which are more easily reproduced and compared with each other in the long run. This could be the case for endo-rectal sonography and pelvic tomodensitometry. As for re-operation itself, it consists essentially in an abdomino-perineal resection possibly associated with radiotherapy.
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PMID:[Importance of a loco-regional follow-up after curative operation in cancer of the rectum or sigmoid]. 355 81

Fourteen cases of pyoderma gangrenosum are reported. Twelve were associated with various diseases: ulcerative colitis, Crohn disease, colic tumor, rheumatoid arthritis, chronic myeloid leukemia, agammaglobulinemia, respiratory infections (2 cases) and post surgical intervention. In 2 cases pyoderma gangrenosum appeared to be primary. The clinical characteristics of the affection make it a very particular type of ulcer: pustular onset, frequent localization to other than leg, rapid eccentric spread, frequent associated morbidity (mainly digestive and hematologic). The pathogenesis is still unknown and the treatment is not well codified.
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PMID:[Pyoderma gangrenosum. 14 personal observations and review of the literature]. 358 90

A rather rare case of tubular-villous adenoma located on the small intestine mucosa in the ileostomy area and its transformation into adenocarcinoma is described. The patient had undergone previously a two-stage colectomy for a giant creeping large intestinal tumor with malignancy in the left and right colic flexure and in the rectum 7 cm apart from the anal margin. Adenocarcinoma of the small intestine developed 5 years later in the ileostomy zone. Ileostomy was reconstructed with the excision of 15 cm of the small intestine. The tumor structure at the site of ileostomy was that of adenocarcinoma, and it infiltrated the muscular layer of the small intestinal wall.
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PMID:[Cancer of the small intestine at the site of an ileostomy]. 367 24


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