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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Thyroid tumors may involve the airway. Eight patients with such invasion are reported; five with invasion of the larynx and three of the trachea. The symptoms varied: five of the eight patients had stridor and hemoptysis, one had hoarseness, and two had no symptoms at all. Endoscopic and radiologic examinations were performed in all patients including computed tomography in six. Six patients underwent total thyroidectomy and two patients, one with paraganglioma and one with hemangiopericytoma, had a hemithyroidectomy. Three patients had a total laryngectomy, one a partial laryngectomy and one a laryngofissure procedure. Tracheal resection was performed in two patients and one had laser excision of the endotracheal tumor involvement. Three patients received postoperative external irradiation. Six of the eight patients are alive with follow-up of 39 to 85 months.
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PMID:Thyroid tumors invading the larynx and trachea. 371 48

A 40-year-old woman was seen with stridor and mediastinal widening secondary to tuberculous mediastinal lymphadenopathy mimicking neoplasm. Initially, stridor could only be controlled with high-dose corticosteroids, but following initiation of antituberculous chemotherapy corticosteroids were withdrawn successfully and the mediastinal lymphadenopathy resolved.
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PMID:Tuberculosis presenting as stridor. 380 Apr 88

A 45-year-old man with a history of intravenous drug use presented with acute respiratory distress. A pulsus paradoxus of 42 mm Hg, accessory respiratory muscle use and stridor were present. Examination of the oropharynx revealed multiple 1 to 2 cm purple lesions of the gingiva and hard palate. A purple tumor mass in the posterior pharynx obstructed the view of the larynx. An emergency tracheostomy was performed resulting in hemorrhage into the respiratory tract. Autopsy revealed disseminated Kaposi's sarcoma and large blood clots in the trachea and main stem bronchus. This case illustrates the occurrence of life threatening involvement of the upper aerodigestive tract with Kaposi's sarcoma and hemorrhagic complications resulting from surgical manipulation.
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PMID:Upper airway obstruction secondary to acquired immunodeficiency syndrome-related Kaposi's sarcoma. 404 18

A newborn male presented with respiratory distress and laryngeal stridor at the time of birth. Laryngoscopy revealed a circumscribed mass in the right vocal cord which was diagnosed as an undifferentiated malignant neoplasm on frozen section. Further light microscopic studies, special stains and electron microscopy disclosed features consistent with a special subtype of sarcoma adopted by the Intergroup Rhabdomyosarcoma Committee. Several authors have also demonstrated similarities between this type of tumor and soft tissue Ewing sarcomas. Nonepithelial malignancies of the larynx are rare in children and are only anecdotally reported in newborns. Histopathologically, the tumors predominantly include rhabdomyosarcomas among other rarer less well documented sarcomas and lymphomas. Although modern chemotherapy and radiotherapy have improved the otherwise grim prognosis of soft tissue Ewing sarcoma, this young patient was only treated with total laryngectomy at ten days of age and is alive and well two years later.
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PMID:Sarcoma of the larynx in a newborn. 618 33

Synovial sarcoma arises most commonly in the lower extremity, particularly in the region of the lower thigh and knee. Yet the occurrence of thus mesenchymal neoplasm in the head and neck area has been convincingly documented, albeit confined almost exclusively to cervical and parapharyngeal sites. Therefore, in view of its rarity in the head and neck, we analyzed a group of 11 synovial sarcomas arising in the orofacial region. The series comprised nine men (82%) and two women (18%). In common with synovial sarcoma at more conventional sites, this is a disease of young adults: ages ranged from 16-49 years (median, 34 years). Topographically, two subsets were delineated, a more common facial group with eight cases (four cheek, two parotid region, one infraorbital, one submental), all arising as gradually enlarging, usually nontender, solitary tumors; and three intraoral ones (two tonsillar, one lingual), two of which were polypoid and one was an exophytic tonsillar mass which presented with hemoptysis and stridor. Follow-up data, obtained for nine patients (range, 1.3-15.0 years), disclosed three (33%) tumor-related deaths, all belonging to the facial group. Treatment, difficult to significantly correlate with survival in this small series, varied from surgical excision alone to a multimodality approach including both irradiation and chemotherapy. Histologically, all the neoplasms revealed characteristic biphasic features, predominantly fibrosarcomatous in one, but, more typically, showing epithelial clefts and/or pseudoacinar spaces in the others. Differential diagnosis, depending on the proportion of the biphasic components, ranged from spindle cell mesenchymal neoplasms to various adenocarcinomas, including those arising in mixed tumors of salivary gland.
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PMID:Orofacial synovial sarcoma: a clinicopathologic study of 11 new cases and review of the literature. 628 38

A case of metastatic tumor in the larynx following successful treatment of a breast carcinoma and a colon carcinoma is presented. The lesion was visible by indirect laryngoscopy, and computed tomography of the larynx assisted in delineating the extent of the disease. The separation of primary adenocarcinoma of the larynx from metastases is discussed, as is the identification of the origin of a metastasis where two separate primaries have existed. Other reports of cancer metastatsizing to the larynx are reviewed. Tumor spread to the larynx may be asymptomatic or may result in hoarseness, stridor and/or airway obstruction.
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PMID:Metastatic cancer to the larynx. Diagnosis and management. 662 9

An extremely rare laryngeal hamartoma causing inspiratory stridor in a 6-week-old infant is reported and the histology discussed. The tumor is benign and responds to simple excision. No other cases have been found in the 20th century American literature.
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PMID:Hamartoma of the larynx: an unusual cause for stridor in an infant. 679 11

We have reported on a 43 years old woman patient, who had fallen ill with an extremely seldom carcinoid tumor arising in the trachea histologically confirmed. Our observations of this woman-patient had been compared with those of 14 patients known from the Anglo-American literature upto 1978. In regard to one French and one Russian collective statistics altogether we come to 24 cases of trachea carcinoids documented in the literature. These are the main symptoms: dyspnea, wheezing, hemoptysis and stridor. Radiation tried at the inoperable patient has proved as ineffective. Today operation seems to be the chosen therapy.
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PMID:[Carcinoid of the distal trachea]. 716 17

At the age of three months an infant rapidly developed signs of cardiac failure as well as in- and exspiratory stridor, caused by an intrathoracic tumor. Thoracotomy and biopsy revealed an intrapericardial tumor, histologically myxosarcoma. In spite of chemotherapy and radiation the infant died at the age of seven months due to multiple intracerebral metastases now histologically rhabdomyosarcoma. This is one of the rare cases of primarily malignant intrapericardial tumors in infancy, and also shows the possible pleomorphism of childhood rhabdomyosarcoma. We know only one further case of pericardial rhabdomyosarcoma where similar histologic changes have been observed.
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PMID:[Intrapericardial rhabdomyosarcoma in infancy (author's transl)]. 732 26

A 24-year-old Caucasian male from Chile developed mediastinal Castleman's lymphoma, hyaline-vascular type, occupying from upper pre-tracheal to sub-carinal region, severely compressing the trachea, left main bronchus, pulmonary artery, and pericardium. Bronchofiberscopy demonstrated complete obstruction of the left main bronchus and the severe telangiectasis of the mucosa. The patient complained of the stridor and shortness of breath. The left thoracotomy had been performed in Chile, but unsucceeded in extirpation because of the adherence and the hypervascularity of the tumor. After 24 Gy irradiation, we performed the right thoracotomy and succeeded in extirpation of the tumor. It was the key for success that we could approach from right side under left sided unilateral ventilation. Castleman's lymphoma is not a rare disease, but the manifestation due to the bronchial obstruction is uncommon. So we present this case and review the literatures.
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PMID:[Castleman's lymphoma presenting marked bronchial obstruction and compression of the great vessels: a case report]. 771 20


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