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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of adenocarcinoma of the prostate that had been incidentally discovered during patient evaluation for trigeminal nerve neuralgia refractory to treatment. Analysis revealed the underlying cause of neuralgia was tumor metastasis to the mandible, which had caused irritation of the fifth nerve. The patient was treated with complete androgenic block and his symptoms improved simultaneously with partial remission of metastasis.
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PMID:[Trigeminal neuralgia. First manifestation of adenocarcinoma of the prostate]. 847 28

Chordoma is a rare tumor in spine. Authors report the case of a 49 years old woman suffering from C5 left neuralgia. Plain films showed an enlargement of C4-C5 left foramina. CT scan permitted to see a lobulated tumor with low density just a few enhancement into septa. MRI showed the tumor with low signal on T1wi, high signal on T2wi and slight enhancement after Gadolinium administration. The extension in the vertebral body is very limited. Differential diagnosis are chondroma or chondrosarcoma and epidermoid cyst. Histology with evidence of a chondroid matrix explain the CT and MR appearance. In this localisation, there is no case reported in the litterature. This is an outstanding case because its extra-osseous localization with a lack of contrast enhancement after injection and its unusual histologic pattern.
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PMID:[A rare case of chondroid chordoma of the cervical spine]. 872 44

This is a case report of acoustic neurinoma which was located exclusively in the cerebellopontine angle (CPA) cistern and which did not extend into the internal auditory meatus ("cisternal" acoustic neurinoma). The 43-year-old female patient had signs of the left trigeminal nerve impairment including left face neuralgia. However, she did not have any neurootological symptom. No abnormal bony changes in the internal auditory meatus (IAM) were found by high-resolution bone-window CT. MRI showed a left CPA tumor of 25mm not extending into the IAM. The tumor was totally removed by the lateral suboccipital approach. It originated from the vestibular nerve medial to the porus acusticus and was located exclusively in the CPA cistern. No tumor extension into the IAM was confirmed. The cochlear nerve was involved in the tumor capsule and could not be preserved. The pathological diagnosis was that it was a neurilemmoma. Early diagnosis of "cisternal" acoustic neurinoma is difficult because it does not show neurootological symptoms in the early stage. The lateral suboccipital approach is appropriate for the removal of a "cisternal" acoustic neurinoma. However, in spite of the good preoperative hearing, the preservation of hearing is difficult because of the large tumor size.
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PMID:[Acoustic neurinoma located exclusively in cerebellopontine angle cistern ("cisternal" acoustic neurinoma): a case report]. 875 81

The prevalence of all neurological disorders in a Japanese town was calculated, with a result of 91.1 per 1,000 population. The prevalence of cerebrovascular disease was 28.8; myelopathy and/or radiculopathy caused by deformity of the spine or disc herniation, 23.9; neuralgia, 11.5; dementia, 10.4; peripheral nerve disturbance, 5.5; epilepsy, 4.4; Parkinson's disease, 2.0; mental retardation, 2.9; brain/spinal tumor, 1.4; headache, 10.8, and vertigo/dizziness, 4.4. The prevalence of headache and vertigo/dizziness was also calculated from the results of the questionnaires sent to inhabitants: headache, 79.6, and vertigo/dizziness, 60.8. Neurological disorders are common in Japan and likely to continue to increase.
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PMID:Prevalence of neurological disorders in a Japanese town. 881 3

The reflex-induced cardiovascular syncope is rarely associated with facial neuralgia and neck neoplasms. We report the case of a male with vasopressor and cardioinhibitor syncopes, despite the implantation of a pacemaker. Because of a glossopharyngeal neuralgia, a neoplasm of the left parapharyngeal fossae is diagnosed. The pathophysiology and the therapeutic approach is discussed.
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PMID:[Syncope associated with glossopharyngeal neuralgia and parapharyngeal tumor]. 903 96

Neuralgia of the trigeminus (NT) is the most common of cranial nerve neuralgias. Its diagnosis is entirely clinical and its most common form of presentation is well understood. Questions of differential diagnosis can emerge with certain entities such as atypical trigeminal neuralgia, short-duration unilateral neuralgiform cephalea of the trigeminus (SUNCT) arising from injection to the conjunctival, lacrimal or other glands, cluster headache, chronic paroxymal hemicrania, pain arising in the teeth and myofacial pain syndrome. The three main causative factors of NT are compression of the nerve root by an artery in the prepontine space, thereby creating an area of demyelinization, compression of the nerve by a tumor, and multiple sclerosis. The first is the most common of the three. NT can be classified as essential in 10 to 30% of patients. Recent advances in magnetic resonance (MR), and its advantages over other imaging systems, have made MR the diagnostic method of choice. The first treatment is medical and the basic drugs involved can be considered classic. Other therapies have been suggested in recent years, however, and should probably be studied further. Two substances stand out among those proposed: tocainide, an antiarrhythmic drug, and pimozide, an antipsychotic. Surgical treatment of NT can address either the cause (tumor or vascular compression) or symptoms, the latter being indicated when medical treatment fails. Surgery can be performed on peripheral nerves, on the gasserian ganglion and on the posterior fossa. The indications, outcomes and possible complications are quite different for each approach, making choice controversial.
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PMID:[Diagnosis and treatment of the patient with trigeminal neuralgia]. 930 3

We report three cases of extradigital glomus tumor mimicking neuralgia. The delay between the onset of symptoms and diagnosis ranged from 6 months to more than 10 years. None of the patients had spontaneous pain. Only palpation of a trigger-zone and movements elicited local pain and a sharp neuralgic pain (greater occipital nerve, medial antebrachial cutaneous nerve, obturator nerve). Albeit atypical, such pain features must suggest the diagnosis of glomus tumor, the confirmation of which is only obtained by histologic examination. Complete excision was fully effective in all three cases.
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PMID:[Extra-digital glomus tumor: a rare cause of neuralgia]. 968 99

Schwannomas of trigeminal nerve account for 0.07% to 0.36% of all intra-cranial tumors. We report three observations about Jefferson's type D tumors, mainly extra-cranial with only small intra-cranial extension, concerning two men and one woman, who were respectively 36, 60 and 63 years old. Two of them presented with facial pain and hypoesthesia in the same territory. The third one developed a diplopia. In all cases, CT scanner analysis evidenced a large hypodense tumor extending in the infratemporal fossa. Temporal lobe and cavernous sinus were pushed aside by the intra-cranial extension. Tumors were hypo intense in T1-weighted image with significant enhancement after gadolinium injection. One of the tumors was a cystic form and in that case, an hyper signal in T2-weighted image was detected in the middle of the lesion. A combined subtemporal and transmaxillary approach was performed in 2 cases. In the third case, the removal of the tumor was only performed by a transmaxillary approach. In this series, there was no surgical mortality. One patient presented a postoperative residual painful anesthesia. In conclusion, extra-cranial schwannomas with intra-cranial extension are specially rare lesions. The most common early symptoms are facial neuralgia, facial hypoesthesia or diplopia. Neuroradiologic investigations, including CT and MRI evidence the precise anatomic site of the lesions. With the help of these techniques, total surgical tumor removal is possible in the majority of cases.
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PMID:[Extracranial trigeminal schwannomas with middle temporal fossa development]. 975 16

Microsurgical approaches for the treatment of pathology located in the ventral thoracic spine using video-assisted thoracic surgery (VATS) allow neurosurgeons to access the disc spaces, vertebral bodies, paravertebral soft tissues, spinal cord, spinal nerves, and sympathetic chain with minimally invasive surgery. This has been associated with substantial clinical benefits including reduced postoperative pain, lower complication rates and shorter recovery times when compared with standard thoracotomy techniques. This article describes the experience at our institution with VATS for discectomy (20 cases), corpectomy and spinal reconstruction (8 cases), thoracic sympathectomy (3 cases), and nerve sheath tumor removal (1 case). The technique can be mastered but requires surgeons to learn the new psychomotor skills needed to perform endoscopic spine surgery. The learning curve is steep. Special training in instructional seminars, surgical skill laboratories, and clinical preceptorships is needed before this surgical approach can be used clinically to treat spinal pathology. VATS has significant advantages compared to standard thoracotomy, including reduced incisional pain and avoidance of the postthoracotomy pain syndrome. If intercostal neuralgia develops postoperatively, it is milder and usually transient compared to the pain associated with standard thoracotomy. Better cosmetic outcomes, earlier mobilization, and faster recovery are added benefits. The surgical techniques are relatively new for neurosurgeons and require dedicated practice to master them. Once the surgical skills are perfected, VATS is feasible for spinal pathology and can be performed safely and effectively.
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PMID:Thoracoscopic approaches to the thoracic spine. 981 Apr 39

Occipital neuralgia might have a various etiology but the most common cause is hypertrophic fibrosis of subcutaneous tissue following trauma to the occipital region, surrounding the occipital nerve. The other important cause of neuralgia is spondylosis of the upper part of the cervical spine (C1-C2). Rare causes are-diabetes, gout and neoplasm. In the presented material we point out the possibility of the occipital neuralgia after surgery in the treatment of the tumours of ponto-cerebellar region and trigeminal neuralgia. We observed the symptoms in two groups of patients and used pharmacological treatment, local blockade and cutting (neuronectomy) of the occipital nerves trunk when the conservative treatment was unsuccessful. We also present the present concepts of occipital neuralgia treatment. In case of severe symptoms, unsuccessful conservative therapy and poor results of the neuronectomy the most indicated therapy is selective posterior rhizotomy.
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PMID:[Occipital nerve neuralgia as postoperative complication. Views on etiology and treatment]. 986 15


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