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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This case report demonstrates the importance of an exact workup in unclear neck pain. An osteoblastoma situated in the pedicule of C6 is described. During 36 months there was no diagnosis made. Only by a CT-scan a tumorous lesion in the pedicule of C6 with the histology of a benign osteoblastoma was found. The therapy consisted in excision of the tumor of C6. A fusion was added because important parts of the joint were involved.
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PMID:Osteoblastoma of the cervical spine. Case report. 273 Mar

A 74-year-old male was seen and evaluated for a pale right tympanic membrane accompanied by posterior neck pain and a mass in the right nasopharynx. Repeated biopsies failed to confirm the expected diagnosis, only yielding lymphatic tissue with chronic inflammation and scarring. The patient was admitted when he suddenly developed ipsilateral cranial palsies, and the radiologic evaluation suggested a vascular tumor. His general condition and neurologic status rapidly declined, and the patient expired shortly after admission. Postmortem examination revealed osteomyelitis of the skull base without evidence of vascular lesion, or middle ear or external canal pathology. The significance of the radiologic evaluation and of this diagnosis are discussed.
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PMID:Osteomyelitis of the skull base--an unusual manifestation. 281 9

Bone scintigraphy was used to diagnose osseous metastasis of prostatic adenocarcinoma in a 10-year-old dog with neck pain and ataxia and a large, sensitive prostate gland. Although radiography revealed a normal spine, prostatic fluid cytologic and ultrasonographic findings were compatible with prostatitis or neoplasia. Scintigraphic hot spots were seen in the axial skeleton, ribs, pelvis, humerus, and femur and corresponded to sites of metastatic prostatic adenocarcinoma.
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PMID:Prostatic adenocarcinoma with osseous metastases in a dog. 304 59

Six conditions cause most of the neck pain complaints seen by primary care physicians: cervical muscle strain or sprain, torticollis, acceleration injury, myofascial pain dysfunction syndrome, and cervical osteoarthritis or rheumatoid arthritis. Most of them can be diagnosed and treated by the primary care physician. Of the more unusual causes, one should not miss a clinical fracture; a herniated cervical disc, spinal cord compression from a disc, or epidural tumor; infection of the disc or the vertebral body; subluxation of the vertebral bodies; or pain referred from the chest or mediastinal structures. MRI offers new opportunity for early diagnosis of myelopathy owing to OA or RA, vertebral osteomyelitis, and metastatic involvement of cervical vertebrae.
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PMID:Neck pain. 306 89

A 2 1/2-year-old female with a sphenooccipital-vertebral chordoma presented with neck pain, torticollis, fever, a lytic lesion of C2 vertebra, and bilateral nodular infiltrates in the lung. The lung biopsy revealed multiple tumor emboli by an enigmatic epithelioid-appearing neoplasm with immunohistochemical staining for vimentin, cytokeratin, and epithelial membrane antigen. A thorough roentgenographic evaluation disclosed a destructive, prepontine mass in the region of the clivus, erosion of the odontoid process, and compression of the cervical spinal cord. The patient died after a clinical course of 3 months. We identified 16 additional cases of metastasizing chordomas in the pediatric-age population; this case is the first to our knowledge with pathologically documented pulmonary metastasis at presentation.
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PMID:Metastasizing chordoma in early childhood: a pathological and immunohistochemical study with review of the literature. 368 9

The seven cases of the foramen magnum tumors were presented with the clinical manifestations and surgical consideration. Early clinical symptoms of the cases with extramedullary lesions were suboccipital neck pain followed by dysesthesia, clumsiness of hand and weakness. On the other hand, early symptoms of the cases with intramedullary lesions were dysesthesia, often followed by swallowing difficulty or hoarsness, which may have some difference from the clinical course of the extramedullary tumor cases. CT scan was remarkably useful in the diagnosis of the foramen magnum tumor. Surgical treatment was done to 6 cases: Five of these cases were operated by suboccipital craniectomy, and one case with an anteriorly located meningioma in the foramen magnum region was operated by transoral approach. Total removal could be performed in the case without damage to the medulla or spinal cord. The surgical treatment was reviewed, and the approach appropriate to tumor location around the foramen magnum should be selected.
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PMID:[Foramen magnum tumor--the diagnosis and surgical approach]. 370 25

We have examined 17 patients suffering from recurrent syncope caused by carcinoma of the head and neck. The tumor originated in the mouth in seven, larynx in six, nasopharynx in three and parotid gland in one, and involved cervical lymph nodes at diagnosis in 12. Sixteen patients had previously had radical neck dissections and 12 had had radiation therapy. Recurrent carcinoma was present in 16. Spells resolved spontaneously in four, improved with treatment in 11 and continued in two. The syncope was spontaneous in 15 and induced only by suctioning or carotid sinus massage in two. Suctioning also produced attacks in four others, as did carotid sinus massage in five of ten tested. Acute severe unilateral head or neck pain preceded spontaneous syncope in 11. Sixteen patients had both profound bradycardia and hypotension during most spells, but ten had syncope with hypotension only, either spontaneously or following cardiac pacing or atropine to prevent bradycardia. Seizure activity accompanied syncope in eight. Anticholinergics improved 7/12, carbamazepine 2/5, carotid ligation 1/1 and intracranial sectioning of the glossopharyngeal nerve 1/1. Local radiation may have helped 4/10. Cardiac pacing was ineffective in 3/3 due to the development of pure vasodepressive syncope. Autopsy in 2/2 showed tumor involving the glossopharyngeal and vagus nerves. Syncope in these patients is under-recognized, frequently is due to vasodepression, and suggests recurrent carcinoma.
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PMID:Syncope from head and neck cancer. 608 17

Among 137 patients with small cell carcinoma of the lung (SCCL) treated on two consecutive protocols, leptomeningeal metastases were documented in 12 patients (9%), 10 antemortem by cerebrospinal fluid (CSF) cytology, one by myelogram, and one only at necropsy. Signs and symptoms included confusion in seven, limb weakness in six, paresthesias in three, headache in two, urinary incontinence in two, and nausea and vomiting, diplopia and neck pain in one patient each. Nine of the 12 patients had evidence of other metastases while three patients relapsed first in the CSF and one had disease only in the leptomeninges. Treatment for this complication including irradiation, intrathecal chemotherapy, or systemic chemotherapy was generally ineffective with a median duration of survival of 50 days (range 5 to 130) after diagnosis of leptomeningeal. Necropsies showed thick tumor deposits along cord, distal nerve roots, cauda equina, and in Virchow--Robbins spaces with deep invasion into adjacent neural substance in six of the seven. Leptomeningeal involvement appears to have become manifest as median survival has increased. CSF cytology should therefore be examined in patients who develop unusual neurological findings during the course of this disease and methods of prevention may need to be considered in future studies.
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PMID:Leptomeningeal carcinomatosis in small cell carcinoma of the lung. 625 38

The primary symptom in patients with tumors in the region of the foramen magnum is persistent neck pain. With the use of microneurosurgical techniques and additional laser therapy, favorable operative results can be obtained. The same holds true for patients harboring difficult to approach lesions such as ventrally located tumors of the craniocervical junction or with brain stem tumors. The advantages of the Nd-Yag-laser therapy are: precise denaturation of tumor tissue with predictable depth effect; adequate delineation of tumors due to different tissue absorption properties; excellent coagulation in the presence of highly vascularized tumors; surgery markedly facilitated due to laser induced shrinkage of tumors.
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PMID:[Use of the Nd-YAG laser in the treatment of tumors in the area of the craniocervical transition]. 653 69

The presence or absence of mobility of the vocal cords is one of the major clinical criteria used in staging laryngeal cancer. Decisions regarding radical laryngectomy may be made on the basis of vocal cord mobility rather than an appraisal of the actual tumor extension. Seventy-one patients in whom the status of vocal cord mobility was clinically proven was studied by computed tomographic (CT) scanning. CT showed two cancers to be more advanced than estimated by normal vocal cord motion due to involvement of the preepiglottic or subglottic space. In three patients with suspected laryngeal tumor presenting with neck pain and hoarseness, CT showed that the sequelae of "occult" trauma had limited vocal cord mobility and had given a false clinical impression of possible tumor. CT correctly predicted vocal cord fixation in 16 of 19 patients with tumor and in eight of nine patients after trauma. In both groups, most patients had multiple findings which could explain fixation. In the tumor group, cricoarytenoid involvement (12 instances) and paralaryngeal space spread (10 instances) were the most frequent. In the trauma group, injuries to the laryngeal skeleton (nine instances) and a variety of soft tissue changes (seven instances) were the most frequent findings, related to fixation.
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PMID:CT of the fixed vocal cord. 677 99


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