Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Oncocytoma is a rare, benign tumor of the kidney of which only 20 cases have been reported previously in the literature. We document 2 additional cases of renal oncocytoma and review the salient gross and microscopic features which characterize this tumor.
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PMID:Oncocytoma of kidney. 49 72

Forty patients with melanocytoma of the optic disc were evaluated to determine their clinical variations and behavior. Follow-up examination of 1 to 19 years was obtained in 27 patients. Of the 27 lesions, four (15%) showed a slight increase in size, and one tumor (4%) decreased in size. The remaining 22 tumors (81%) have not yet demonstrated ophthalmoscopic changes. In spite of occasional growth, the melanocytoma is a benign tumor that requires no treatment.
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PMID:Clinical and follow-up studies of melanocytomas of the optic disc. 53 92

Papillary cystadenoma lymphomatosum (Warthin's tumor) is generally considered to be a benign tumor. However, a few well-documented cases of malignant transformation have been reported. In each case, the patient had received radiotherapy to the neck region where the tumor later developed. This paper reports a case of malignant transformation of a papillary cystadenoma lymphomatosum (PCL) in a patient who had not received radiotherapy. Light and electron microscopy documented this transformation and clearly identified the malignant portion of the tumor as having its origin in a benign PCL. The literature is reviewed and a discussion of pathology presented.
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PMID:Malignant transformation of a Warthin tumor: case report, review of the literature, and discussion of pathology. 54 51

True teratomas of the neck in adults are unusual neoplasms. Their clinicopathologic aspects are distinctly different from the counterpart tumor of the neonate and infant. While the latter is almost always a benign tumor, adult teratomas are both histologically and clinically malignant neoplasms. To our knowledge, we report the tenth case of a teratoma of the neck in an adult.
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PMID:Teratomas of the neck in adults. 64 21

Oxyphilic adenoma of the parotid gland is a rare benign tumor. In the case presented, increased concentration of 99mTc-pertechnetate was seen in the tumor. The only other neoplasm which is known to consistently concentrate pertechnetate is papillary cystadenoma lymphomatosum (Warthin's tumor).
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PMID:Oxyphilic adenoma of the parotid gland. Identification with 99mTc-pertechnetate. 67 38

No more than 40 cases of inverted papilloma (IP) of the urinary bladder have been reported in literature. The author presents 2 observations of IP in both of which the epithelial transitional cellular structures showed submerged pseudoinvasive growth and a peculiar inversion of the villous strucure. The tumor is benign clinically and histologically, its benign nature is confirmed by the remote results of observations. Despite the fact that the histogenesis of IP is not quite clear yet, the author, as most other investigators, classify IP according to the International Histological Classification as benign tumor differing from common papillomas of the urinary bladded only in the direction of the growth and the arrangement of villous structures.
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PMID:[Inverted papilloma of the bladder]. 67 57

We report the clinical and histopathologic features of an osseous choristoma of the choroid that appeared in a 26-year-old woman. Her diagnostic evaluation included a radioactive phosphorus (32P) uptake test, which was 270% positive and led us to believe that the lesion was an atypical malignant melanoma. The extent of true ossification within this tumor, seen microscopically, explains the false-positive uptake of radioactive phosphorus by this benign tumor; it is well known that bone avidly accumulates radioactive phosphorus. We recommend that all "atypical choroidal melanomas" be studied for the presence of bone, with bone-free roentgenograms, ultrasonography, and possibly, computerized tomographic scans before 32P testing or enucleation. This, to our knowledge, is the second histopathologically proved case of an osseous choristoma of the choroid to be reported in the literature.
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PMID:Osseous choristoma of the choroid simulating a choroidal melanoma. Association with a positive 32P test. 69 26

The histochemical and electron microscopic findings in seven cases of dermal duct tumor are described. All seven of the patients were elderly, and five were women. The tumors were small flesh-colored or red papules located most often on the head and neck region. Intense phosphorylase and moderate respiratory enzymes characterized the histochemical reaction of the tumors. The following three types of tumor cells were recognized ultrastructurally: clear, dark, and luminal. The tumor was principally composed of clear cell proliferation around a regular ductal lumen. In addition, melanocytes, Langerhans' cells, and lymphocytes were occasionally seen within the tumor masses. An intact basal lamina and few hemidesmosomes with no detectable actin-like microfilaments were the features of the tumor-stroma interface. Our study results showed that the dermal duct tumor is a benign tumor with eccrine dermal ductal differentiation.
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PMID:Dermal duct tumor: a histochemical and electron microscopic study. 71 15

A case of acquired digital fibrokeratoma is presented. The asymptomatic cylindrical tumor preferably occurs during the third to sixth decade of life and affects mainly the fingers. Histologically one finds a cylindriform connective tissue proliferation surrounded by an akantholytic band of epidermis with papillomatous changes and hyperkeratosis. For differential diagnosis rudimentary supernumerary digit, cutaneous horn and granuloma pyogenicum are to be considered. Therapy consists of excision of this benign tumor of hitherto unknown origin.
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PMID:[The acquired digital fibrokeratoma]. 72 75

A case of benign ascending choledochal papillomatosis is reported. The pathogenetic, diagnostic and therapeutic points of view and the prognosis of this disease are discussed in the light of cases so far communicated in the literature. Although, histologically, the choledochal papillomatosis is a benign tumor, its clinical course corresponds to that of a malignant growth. That being so, a radical removal of the tumor is guaranteed exclusively by duodenopancreatectomy.
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PMID:[Ascending choledochal papillomatosis (author's transl)]. 81 96


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