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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The tumor of lutein cells of the ovary during pregnancy was first described by Sternberg (1963) as "luteoma of pregnancy". Up to 1973/74 66 cases were published. This benign tumor occurring only during pregnancy probably arises under stimulation of chorionic gonadotropin and may cause a virilization of the mother and female infant. After birth the ovarian tumors regress spontaneouly. Lutein cell tumors are usally discovered incidentally at laparotomy (cesarean section) in late pregnancy and require no radical surgical treatment. The feature of these tumors and some related questions are discussed on the basis of on own observation being, to our knowledge, the first case of this type in Central Europe.
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PMID:[Luteoma of the ovary during pregnancy (author's transl)]. 20 35

Data on 148 cases of liver tumor in women have been registered. Analysis of these data shows that 1) the average age is 30.3 years; 2) 85% of the patients had a history of oral contraceptive use; 3) pain was the most usual symptom followed by incidental discovery during an operation; 4) 19 were hepatomas, 56 were adenomas, 67 were focal nodular hyperplasia, and 6 were unclassified; and 5) 67% of the benign tumors were in the right lobe, there were 15 cases of multiple focal nodulat hyperplasia and 11 cases of multiple adenomas, and several of the adenomas were only partially encapsulated. The histopathologic differentiation of focal nodular hyperplasia from adenomas can be obtained by detection of the presence of bile duct epithelium in focal nodular hyperplasia; this is always absent in adenoma. Of the 19 patients with hepatomas, 12 have died (7 had metastasis, 3 deaths were related to the operative status), 2 are near death, and 5 are alive following resection. Treatment in most cases was resection or lobectomy, but biopsy only was performed in 22 cases of benign tumor. Follow-up of these cases should add to the knowledge about the necessity extent of surgery. The possible relationship of oral contraceptive use to liver oncogenesis is as yet undefined, but the incidence of tumors is very low considering the numbers of women who are current users of steroid contraceptives. Benign tumors have been reported to involute after discontinuation of steroidal medication. This therapeutic dilemma may be resolved when the patients in this series who underwent biopsy only have been followed for a longer interval.
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PMID:Liver oncogenesis and steroids. 21 80

A tumor at the temporomandibular joint is reported, which so far has not yet been described. Histologically it turned out to be a combination of synovialchondroma and giant cell tumor of tendon sheath. By reason of the microscopic picture and the course of 2 1/2 years without relapse it is a benign tumor. In postoperative x-rays of the mandible a thickening and sclerosis as well as cystic areas of increased translucence at the place of removal of the tumor were found, which had already existed preoperatively in a lower degree.
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PMID:[Giant cell tumor of tendon sheath in association with synovialchondroma. An unusual tumor-combination at the temporomandibular joint (author's transl)]. 21 44

In human tumor tissues of different degrees of differentiation--nevus-cell-nevus, basalioma, malign melanoma--the cAMP and cGMP content was determined and compared with the corresponding normal values. It is demonstrated that the quotient of the cAMP to the cGMP values is of importance rather than the latter values for themselves. For the benign tumor, this quotient differs only slightly from that of the adjacent normal, sound tissue. On the other hand, for the two malign tumors a drastic decrease of the quotient as compared to that of the normal tissue was found to occur.
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PMID:[Ratio of cyclo-3':5'-adenosinemonophosphate to cyclo-3':5'-guanosine-monophosphate in human tumor tissue]. 21 50

Four cases of spontaneous acute hemoperitoneum due to rupture of a liver tumor are presented. The resulting acute abdomen was the first manifestation of the neoplasia. The four tumors corresponded histopathologically to a cavernous hemangioma, a bening adenoma related to anabolizing androgens, and two hepatocarcinomas in cirrhotic livers. All of the patients presented abdominal pain and shock, the characteristics of which are described in this report. One of the patients died due to cardiac arrest before surgical treatment. Emergency surgery was performed on the other three, consisting of left hepatic lobectomy and ligature of the hepatic artery for the hemengioma, and segmented hepatectomy for the adenoma and the hepatocarcinoma. Only the patient with benign tumor survived. Lastly, the authors review the literature, commenting on the clinical, physiopathologic, therapeutic, and prognostic aspects.
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PMID:[Acute abdomen due to hemoperitoneum as the first manifestation of a liver tumor. Report of four cases (author's transl)]. 21 4

A review of reported cases of cystic metanephric tumors is given. It is shown that among these neoplasms two distinct pathologic entities exist: the cystic nephroblastoma and the benign multilocular cystic nephroma. The former, a benign variant of Wilms' tumor, is found in children of younger age. Its possible precursor is the infantile form of nephroblastomatosis. The second neoplasm, a clinically and biologically benign tumor, occurs in older children and in half of the cases it is also encountered in adults. It derives from metanephric hamartomas which have their origin in the huvenile form of nephroblastomatosis.
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PMID:[Benign multilocular cystic nephroma versus cystic nephroblastoma. A review and classification of cystic metanephric neoplasms (author's transl)]. 22 12

Electron microscopy of a sclerosing angioma of the lung, a coincidental finding in the upper lobe of a 32-year-old woman. The rare, benign tumor, whose vascular proliferation by light microscopy is reminiscent of an angioma, exhibits a clear epithelial structure by electron microscopy. The tumor may develop out of immature pneumocytes. The paper discusses histogenesis and problems of differential diagnosis (potential confusion with carcinomas).
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PMID:Sclerosing angioma of the lung. Case report and electron microscope investigation. 23 52

Chondromyxoid fibroma in the jaws is an extremely rare, benign tumor. The lesion is relatively more common in the long bones and mainly occurs in adolescents and young adults. The treatment of choice is local resection of the tumor. Recurrences are not uncommon, especially when curettage was the method of treatment. Differentiation from chondrosarcoma is mandatory as treatment and prognosis are dissimilar.
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PMID:Chondromyxoid fibroma of the mandible. Case report. 41 15

Lipofibroma of the median nerve or its cutaneous branches is a rare benign tumor. The diagnosis is usually made at surgical exploration of a mass in the distal part of the forearm, the wrist, the palm, or the digits of the hand, which may be asymptomatic or associated with symptoms of carpal-tunnel syndrome. The diagnosis should be made when exploration reveals fusiform enlargement of a segment of the median nerve or its cutaneous branches without hypertrophy of the regional tissues. The tumor is limited to within the epineurial sheath, which is intact, shiny, orange-yellow, firm, thick, and non-resilient to dissection. The nerve tumor does not infiltrate the surrounding tissues nor do the surrounding tissues infiltrate the nerve. If the epineurium is opened, the nerve fibers are found to be inseparably infiltrated by fibrous and fatty tissues. Histologically, these are of epineurial, perineurial, and endoneurial origin. A forzen-section biopsy of a palmar cutaneous branch is suggested to confirm the diagnosis. Once the diagnosis is confirmed, the treatment should be limited to release of the fascia over the involved nerve. The tumorous part of the median nerve was partly or completely excised in seven of twenty-six cases reviewed in the literature and this report. It is to emphasize a conservative approach when such a tumor of the median nerve is encountered at surgery that we describe two more cases.
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PMID:Lipofibroma of the median nerve in the palm and digits of the hand. 42 10

The clinicopathologic findings in 24 cases of Brenner tumors of the ovary, seen at the University of Michigan Medical Center between 1941 and 1975, are reported. Abnormal uterine bleeding was the most common presenting symptom. Associated endometrial changes ranging from glandular hyperplasia to invasive adenocarcinoma were found in 5 cases. No consistent relationship was found between the thecomatous appearance of the stoma of the tumor and endometrial changes suggestive of estrogen stimulation. Seven patients had other types of ovarian neoplasms. Four patients had bilateral brenner tumors. Three Brenner tumors were histologically and clinically malignant. This study suggests that the presumed potential steroidogenesis of the Brenner tumors of the ovary may not always be a product of the thecalike cells of the stroma. The need for further biosynthetic studies is reemphasized. Furthermore, when conservative therapy of a benign tumor is attempted, the contralateral ovary should be carefully examined and a wedge resection considered. The optimal therapy of malignant Brenner tumors has not been established; adequate surgery and careful staging followed by individualized adjuvant therapy is recommended.
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PMID:Brenner tumors of the ovary. 45 Mar 68


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