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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Paraganglioma though rare in ENT-pathology are considered the most common middle ear tumors. A few of them show some particularities in its growing mood, for instance under the appearance of a banal polyp lodging in the external ear canal, perhaps the polyp represents only the outer portion of a deeper larger process encroaching the underlying bone, which threat heavy complications, specially at attempts of removal without the prior due complementary explorations. The case reported by the authors was a quickly evolutive syndrome with the polyp associated to otorrhea and facial paresia. The verification of the bone destruction make credible the actual diagnosis, malignant tumor of the temporal bone. Afterwards profuse otorragia suggested the glomic tumor. The paper emphasizes the clinic malignancy of theses growths in spite of their histologic benignity, owing both to its speed evolution and destructive power.
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PMID:[Jugular paraganglioma: presentation in the form of an aural polyp]. 215 46

A 64-year-old male was admitted to our hospital suffering from dysphagia and dyspnea. The chest X-ray films and chest CT films revealed huge tumor in his upper-anterior mediastinum. The filling defect at lower rim of the left brachiocephalic vein on venography indicated malignant potential of the tumor. There was no abnormal value in blood and urine examinations except CA 19-9 which was 31.8 U/ml. The tumor was resected with bilateral pleura, pericardium and left brachiocephalic vein. Macroscopically the specimen accompanied with a lot of bleeding spots was soft and yellow and has no capsule. The size of tumor was 15 X 13 X 8 cm and its weight was 865 gm. No tumor recurrence was found until present time: two years after surgical therapy followed by adjuvant radiation therapy (60 Gray). Though histological findings of anterior part of the tumor were consisted of "Zellballen" cells and bleedings, the posterior part had cell atypia and invasion into vessels. These cells were slightly positive on Keratin stain and on NSE stain. Typical findings of paraganglioma were also indicated by electron microscopy: those findings were more chief cells, fewer sustentacular cells, abundant mitochondria and few dense-cored granules which are thought to secrete hormonal substances. Judging from these clinical and pathological results, this tumor was diagnosed nonfunctional aortico-pulmonary paraganglioma. Mediastinal paraganglioma is a very rare tumor. There is no report of malignant aortico-pulmonary paraganglioma in Japan after Glenner and Grimelys' study concerning extra-adrenal paraganglion system.
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PMID:[A case of malignant aortico-pulmonary paraganglioma]. 216 23

Paragangliomas of the cauda equina are not so rare as said in the literature. Two additional cases are presented with a global analysis of the 59 cases from the literature. The diagnosis of this pathology greatly benefit of the use of immunostainings as the cells are often neuron-specific enolase, neurofilament protein and somatostatin positive so that electron microscopy is thus no longer mandatory for establishing the diagnosis. In addition, we report the first magnetic resonance images of this tumor at this location.
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PMID:Paraganglioma of the cauda equina. Report of 2 cases and review of 59 cases from the literature. 217 37

The carotid body paraganglioma is a rare tumor that arises from the autonomic nervous chemoreceptor. It can be diagnosed by contrast angiography. A patient in whom a carotid body chemodectoma was imaged with In-111 labeled monoclonal anticarcinoembryonic antigen (anti-CEA) antibodies is described. There was marked accumulation of the antibody into the tumor but little blood pool activity at 25 hours. The removed tumor, which was examined immunohistochemically, was positive for vimentin, GFAP, NF 68, SYP, and S-100; and negative for CEA, desmin, and cytokeratin. The tumor was a paraganglioma that accumulated antibody with nonspecific mechanism of uptake.
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PMID:Radioimmunodetection of chemodectoma by In-111 labeled anti-CEA antibody. Case report and review of the literature. 217 86

Carney's triad is a combination of at least 2 of 3 tumor sites: multiple gastric leiomyoblastoma, pulmonary chondroma and paraganglioma, most often extra-adrenal and secreting. Thirty-three cases have been published; we report a new case in a 20 year-old woman, with multiple gastric leiomyoblastomas, liver metastasis, and bilateral pulmonary chondroma. The research of paraganglioma, in regard to Carney's disease, led to the discovery of corticoadrenal adenoma.
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PMID:[Carney's triad: a new case associated with adrenal cortex adenoma]. 219 Aug 57

Extra-adrenal non-functioning retroperitoneal paragangliomas are rare tumors. We herein report a case of retroperitoneal tumor which posed a diagnostic and management problem. Review of the literature shows only 16 previously reported cases of extra-adrenal paraganglioma which underwent complete surgical excision.
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PMID:Extra-adrenal non-functioning paraganglioma. 219 28

Paraganglioma of the urinary bladder is a very rare tumor, which is usually diagnosed on the basis of its endocrine symptoms because of the excretion of vasoactive substances. One case of asymptomatic paraganglioma detected by chance is described, it was misdiagnosed as hemangioma because of its marked suburothelial vessel proliferation.
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PMID:[Asymptomatic paraganglioma of the bladder wall with unusual extensive submucous vascular proliferation]. 221 4

Isolated vertebral body metastases from paraganglioma are exceedingly rare. They have been reported to occur in the presence of active primary tumor in the neck, local recurrence, or widespread metastases. A unique case of carotid body tumor (paraganglioma) is reported with the following features: (1) multiple vertebral body metastases (C6, T9, and L3) presenting with spinal cord compression, and no evidence of local recurrence or other metastatic disease; (2) absence of mitoses on the original specimen or the metastatic deposit; and (3) a prolonged interval (9 years) to the development of symptomatic metastases.
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PMID:Multiple spinal metastases from paraganglioma. 222 78

We report two cases of primary paraganglioma of the urinary bladder. Case 1. A 61-year-old man was hospitalized with the chief complaints of gross hematuria, dysuria and headache. The patient had a history of hypertension. Cystoscopy disclosed a nonpapillary, sessile tumor in the retrotrigonum of the bladder. An attack of paroxysmal hypertension was induced by bimanual palpation of the tumor, and paraganglioma was suspected. Partial cystectomy with staging pelvic lymphadenectomy was performed. Case 2. A 65-year-old man was hospitalized with the chief complaints of gross hematuria and urinary retention. The patient had no history of hypertension. Cystoscopy disclosed a nonpapillary tumor in the right lateral wall of the bladder. Transurethral resection was performed with no cardiovascular complication. Prostatic needle biopsy showed the histological evidence of prostatic adenocarcinoma. Radical retropubic prostatectomy with limited lymphadenectomy was performed. There was no histological evidence of lymph node involvement of paraganglioma or adenocarcinoma. The histological and biochemical examinations revealed a chromaffin positive, functioning and non-malignant tumor in Case 1, and a chromaffin negative, non-functioning and non-malignant tumor in Case 2. In total, 29 cases of primary paraganglioma of the urinary bladder have been so far reported in Japan. The tumor recurrence, multiple or metastases were recorded in 8 of 29 cases (27.6%), mainly in regional lymph node metastases. We recommend lymphadenectomy at the initial operation, irrespective of pathological finding of the primary paraganglioma of the urinary bladder.
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PMID:[Primary paraganglioma of the urinary bladder: a report of two cases]. 223 62

Paraganglioma is rare neoplasm. The authors report two new cases. The first case was a 36 year-old woman who presented with post-micturitional episodes of hypertension. Radiologic and endoscopic investigations showed a left submucosal bladder neck tumor. A partial cystectomy was performed under neuroleptanalgesia. The postoperative course was uneventful is simple. The second case was a 61 year-old woman who presented with a non secreting para-aortic paraganglioma.
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PMID:[Extra-adrenal pheochromocytoma. Report of two cases]. 225 50


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