Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027651 (tumor)
685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Apart from other lesions, 51 renal neoplasms were induced in rats by administration of methylethy-, dimethyl- and phenylmethylnitrosourea. 3 tumors originated from the renal pelvis and were classified as transitional cell papilloma (1) or transitional cell carcinoma (2). 48 neoplasms were considered as "mesenchymal tumors". These growths were regarded as rat kidney specific tumors. They display a wide spectrum of histological structures: spindle cells which are capable to differentiate into smooth muscle cells, fibroblasts, angioblasts, fat cells, and even into cartilage thus forming the typical microscopical features which are completed by the tendency of mesenchymal cells to swirl around preexisting renal tubules in several closely investing layers. As the cell of origin is not yet established the term "mesenchymal tumor" seems to be the most suitable one. There is no basis for classifying these tumor as nephroblastomas and the two entities should be strictly separated.
...
PMID:Tumors of the rat kidney induced by nitrosourea compounds. 51 Apr 52

We encountered inverted papilloma of the conjunctiva in three cases. To the best of our knowledge, this tumor, which typically involves the nose, paranasal sinuses, and lacrimal sac, has not been described previously in the conjunctiva. Two of the tumors occurred as purely inverted lesions of the inner canthal region )caruncle and plica) and the third as a mixed inverted-exophytic papilloma over the tarsus. Melanotic pigmentation in one of the lesions was clinically confused with malignant melanoma. Because of the high incidence of recurrence of these tumors in the sinuses and lacrimal sac, and their unknown biologic behavior in the conjunctiva, inverted papillomas should be removed completely and the patients carefully observed.
...
PMID:Inverted papilloma of the conjunctiva. 51 11

The radiological characteristics of intraventricular tumors were studied with special reference to differential diagnosis from paraventricular tumors by careful analysis of seven cases intraventricular tumors and five cases paraventricular tumors. As, in the radiological term, intraventricular tumors have been dividied into two groups according to their location by Bernasconi et al., seven cases intraventricular tumors reported in this paper were also divided into two groups; 1) 2 cases ependymom occupying the frontal horn and the body of lateral ventricle, 2) 4 cases meningioma and one plexus papilloma occupying the trigone and the adjucent regions. In case of tumors belonged to group 1, the filling defect showing the circumference of tumors and the associated unilateral hydrocephalus were characteristic findings on the ventriculogram, while the depression of ventricular wall was observed in paraventricular tumors. Angiographic characteristics in group 1 tumors were the splay of subependymal veins of the medial group from those of lateral group and the increased density of deep veins due to raised circulation, and these findings demonstrated in all cases of ependymoma reported here. On the other hand, in all meningiomas belonged to group 2, the hypertrophia of choridal arteries was noticed in the angiogram. Moreover, the anterior choroidal artery was shown to be divided into two branches at its plexal segments, and the tumor stain at the trigone always lied between these two branches. We named this dissociation of these two plexal branches due to tumor as "flare sing". This is considered to be specific finding for a trigone meningioma, and this "flare sing" was observed in all of our 4 cases meningioma. In two cases out of four, the inferior ventricular vein was displaced anteriorly delineating the anterior margin of the tumor. This again is considered as a sign indicating the tumor occupying the trigone and adjacent regions.
...
PMID:[Radiological diagnosis of the lateral ventricle tumor (author's transl)]. 55 45

Choroid plexus papilloma is a rare intracerebral neoplasm that occasionally disseminates along the neuraxis. The fine structure of such a metastatic papilloma appears to correspond very closely to that of normal choroid plexus. Lack of capillary endothelial pores is the only meaningful difference. There does not appear to be an ultrastructural feature that is unique to disseminating choroid plexus papilloma.
...
PMID:Disseminated choroid plexus papilloma. An ultrastructural study. 57 91

Forty patients with urinary bladder tumors (26 cancer and 14 papilloma) were investigated by clinical and immunological methods. Patients with Stage I and II bladder cancer had a decrease in their delayed cutaneous hypersensitivity reactions in comparison to healthy controls. The same was found in patients with proliferating papillomas (WHO I) and benign papillomas. Patients with carcinoma in Stages III and IV had a reduced reactivity to recall antigens and could be immunized to a significantly lesser degree with primary antigens. In most cases a transurethral resection of the tumor was followed by radiotherapy. In four patients local immunotherapy was performed after resection of most of the tumor mass.
...
PMID:[Clinical and immunologic investigations of patients with urinary bladder tumors (author's transl)]. 63 16

An additional case of a benign polypoid tumor of the urinary bladder is reported, the first one observed at autopsy and the first in which photographic documentation of the gross appearance is presented. The lesion was first described as an adenomatoid polyp in 1927. We consider the subsequent (1963) designation of inverted papilloma misleading. Because its histologic morphology bears a striking resemblance to Brunn's nests and because the term papilloma of the urinary bladder connotes potential malignant change, we propose the designation brunnian adenoma. All cases previously reported have been benign.
...
PMID:Brunnian adenoma (inverted papilloma) of the urinary bladder: report of a case. 64 Jun 46

No more than 40 cases of inverted papilloma (IP) of the urinary bladder have been reported in literature. The author presents 2 observations of IP in both of which the epithelial transitional cellular structures showed submerged pseudoinvasive growth and a peculiar inversion of the villous strucure. The tumor is benign clinically and histologically, its benign nature is confirmed by the remote results of observations. Despite the fact that the histogenesis of IP is not quite clear yet, the author, as most other investigators, classify IP according to the International Histological Classification as benign tumor differing from common papillomas of the urinary bladded only in the direction of the growth and the arrangement of villous structures.
...
PMID:[Inverted papilloma of the bladder]. 67 57

An extremely rare tumor of the III brain ventricle, a squamous cell papilloma, in a man of 49 is described. The localization of the neoplasia without any topical association with the vascular plexus confirms the opinion that squamous cell papilloma of the III ventricle belongs to the group of craniopharyngiomas.
...
PMID:[Squamous cell papilloma of the 3rd cerebral ventricle]. 67 36

Electron-microscopic and immunohistological studies show the cross-reactivity of an antigen in verruca plana, condyloma acuminatum and laryngeal papilloma. If this antigen is identical with papova virus or a tumor-performed antigen, cannot be distinguished definately. The fact that sera of patients bearing condylomata acuminata show strong antigen-antibody-reaction with tissue-sections of laryngeal papilloma by means of immunofluorescence microscopy, is discussed in a probably therapeutical point of view.
...
PMID:[Papilloma of the larynx. Immunology (author's transl)]. 68 80

The carcinogenic activity of orally administered N-bis(2-hydroxypropyl)-nitrosamine (DHPN) in male Wistar rats was evaluated with respect to its dose. DHPN was administered at two doses, 100 ppm and 500 ppm, in the drinking water to rats for 25 to 52 weeks. Tumors developed in the lung, liver, and thyroid of rats receiving 100 ppm DHPN and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats receiving 500 ppm DHPN. The principal target organ was the lung in rats receiving either 100 or 500 ppm DHPN, indicating that the carcinogenic action of these doses of DHPN was similar to that of higher doses previously reported. Histologically, the tumors were adenoma, adenocarcinoma, squamous cell carcinoma, and combined carcinoma of the lung, hepatocellular carcinoma and hemangioma of the liver, adenoma and adenocarcinoma of the thyroid, squamous cell papilloma and carcinoma of the esophagus, renal cell and transitional carcinoma of the kidney, and transitional cell carcinoma of the urinary bladder. No pancreatic tumors were observed.
...
PMID:Effect of dose on the carcinogenic activity of orally administered N-bis(2-hydroxypropyl)nitrosamine in rats. 71 Aug 6


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>