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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intratracheal tumors are rare in children. A case is reported of a two-year-old female child with a fibrous histiocytoma of the trachea which caused severe respiratory obstruction and persistent right middle lobe pneumonia. Fibrous histiocytomas are basically benign tumors of histiocytes and have been mistaken for other tumors such as fibroma, sclerosing hemangioma, neurilemoma, fibromatosis, hemangiopericytoma, fibrosarcoma, and some primitive sarcomas. Fibrous histiocytomas have not been reported in the trachea or bronchi. The patient was treated with endoscopic removal of the tumor, and has remained free of disease to this date.
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PMID:Fibrous histiocytoma of the trachea. 21 68

Four cases of spontaneous acute hemoperitoneum due to rupture of a liver tumor are presented. The resulting acute abdomen was the first manifestation of the neoplasia. The four tumors corresponded histopathologically to a cavernous hemangioma, a bening adenoma related to anabolizing androgens, and two hepatocarcinomas in cirrhotic livers. All of the patients presented abdominal pain and shock, the characteristics of which are described in this report. One of the patients died due to cardiac arrest before surgical treatment. Emergency surgery was performed on the other three, consisting of left hepatic lobectomy and ligature of the hepatic artery for the hemengioma, and segmented hepatectomy for the adenoma and the hepatocarcinoma. Only the patient with benign tumor survived. Lastly, the authors review the literature, commenting on the clinical, physiopathologic, therapeutic, and prognostic aspects.
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PMID:[Acute abdomen due to hemoperitoneum as the first manifestation of a liver tumor. Report of four cases (author's transl)]. 21 4

This article describes 41 examples of an unusual fibrohistiocytic sarcoma which occurred primarily in the extremities of young individuals between the ages of 5 and 25 years (median 13 years). It manifested as a nodular subcutaneous growth that seldom caused tenderness or pain, and clinically was often mistaken for a hematoma or a hemangioma. Grossly, the tumor presented as a circumscribed, multinodular or multicystic, hemorrhagic mass that ranged in size from 0.7 to 10 cm (median 2.5 cm). On microscopic examination, it consisted principally of 1) solid arrays or nests of fibroblast- and histiocyte-like cells, not infrequently containing varying amounts of intracellular hemosiderin or lipid, 2) focal areas of hemorrhage or hemorrhagic cyst-like spaces, sometimes occupying the major portion of the tumor, and 3) aggregates of chronic inflammatory cells, chiefly lymphocytes and plasmacytes, a feature that caused confusion with a lymph node metastasis in several cases. Follow-up information, available in 24 patients, revealed a variable clinical course. Twenty-one patients were alive, 11 with recurrence (including one with 9 recurrences in a 21-year period) one with recurrence and metastasis and one with metastasis. Three patients had died of metastasis 1, 3, and 13 years respectively, after the initial surgical therapy. The exact histogenesis is still obscure. Most likely it is a tumor of fibroblast- and histiocyte-like cells, akin to malignant fibrous histiocytoma, but different in its age incidence, microscopic appearance and behavior.
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PMID:Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. 22 36

The authors present 8 cases of rare tumors of the nasal septum and define a number of characteristic points on the basis of each of them. The following are presented: --a malignant nevus, the rarety of E.N.T. sites of such tumors is emphasized, as well as important role of immunotherapy in their treatment, alongside surgery and radio-therapy. --a keratoacanthoma, difficult in terms of differential diagnosis from a basal cell carcinoma. -- a cavernous hemangioma, excision of which must be wide if recurrence is to be avoided. --one very hemorrhagic mixed tumor. --one case of pseudo tumoral tuberculosis in a woman with no known past history of tuberculous disease. --one very painful glomus tumor, radical treatment of which is surgical, in preference to radiotherapy. --two cylindromas of the septum, one taking the form of a large, angiomatous polyp, which puts in question the name of cystic adenoid carcinoma, suggested for these non-cutaneous tumors.
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PMID:[Rare tumors of the septum. 8 reported cases (author's transl)]. 23 Jul 77

A series of sixty lung tumors operated during 1977 were histoenzymatically investigated (12 macrocellular carcionomas, 4 microcellular, 18 epidermoid, 18 cylindrocubic, 2 bronchiolo-alveolar cell carcinomas, 4 lung fibroblastic sarcomas, and 2 benign lung tumors: a haemangioma and a carcinoid tumor). There were tested 25 enzymes, hydrolases and oxidoreductases of different metabolic pathways. The histoenzymatic analysis of the neoplastic lung tissue compared with the normal adult human lung tissue pointed to a shifting of the metabolic balance, with the decrease of enzyme activities belonging to the Krebs tricarboxylic acid cycle and with the increase or maintenance of the level of enzymic activities belonging to the Embden-Meyerhoff-Parnas pathway and to the pentose shunt. The enzymes intervening in the protidic activity in all the malignant tumors of the lung. Some hydrolases were also more active lung tissue pointed out the existence of close relations between the normal epithelia and the cylindrocubic and bronchiolo-alveolar types, and of distant ones with the epidermoid and microcellular carcinomas which suffered more accentuated ecogenetic influences (stopping of differentiation/maturation, metaplasia) during the complex oncogenetic process.
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PMID:Histoenzymology of the lung. V. Histoenzymatic analysis of sixty lung tumors. 23 Dec 4

Electron microscopy of a sclerosing angioma of the lung, a coincidental finding in the upper lobe of a 32-year-old woman. The rare, benign tumor, whose vascular proliferation by light microscopy is reminiscent of an angioma, exhibits a clear epithelial structure by electron microscopy. The tumor may develop out of immature pneumocytes. The paper discusses histogenesis and problems of differential diagnosis (potential confusion with carcinomas).
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PMID:Sclerosing angioma of the lung. Case report and electron microscope investigation. 23 52

Described by Lloyd and Dennis in 1963, Cowden's disease is a familial affection in which are found associated lesions of the buccopharyngeal mucosa (papillomatosis, papules, scrotal tongue), various types of skin lesions (verruciform keratotic papules, papilloma, lipoma, angioma, etc...), visceral manifestations usually related to lesions in the thyroid, breasts, or digestive tract (hamartoma or malignant tumors), and skeletal dysmorphism. The two patients were from different families, were aged 65 and 28 years, and had presented for consultation because of buccal mucous membrane papillomatosis, and in one case, hemorrhagic gingivitis. Cowden's disease was diagnosed from the clinical examination, past history, and investigations after hospital admission. The main value of the mucosal and cutaneous lesions is their diagnostic significance, enabling a synthesis of the multiple dispersed manifestations to be made, and a possible visceral tumor to be discovered in the early stages.
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PMID:[Cowden's disease. A report on two cases in Swiss families (author's transl)]. 29 Nov 9

Spontaneous eye movements and responses to visual and vestibular stimuli were recorded in 30 patients with pontine angle tumors (26 neurinomas, 2 meningeomas, 1 chosteatoma, 1 angioma). Pre- and postoperative recordings in most cases showed a bilateral dimunition of horizontal optokinetic nystagmus (OKN) that prevailed towards the side contralateral to the tumor. This is explained by a homolateral floccular lesion and cannot be the consequence of spontaneous nystagmus or asymmetrical gaze nystagmus. The predominance of a homolateral OKN-diminution often described in the literature was found in advanced cases or post-operatively as a sign of pontine reticular formation damage. The neighbourhood of the flocculus to the VIIIth nerve and animal experiments with floccular lesions causing a contralateral OKN diminution support out explanation. Additional arguments for damage of cerebellar oculomotor functions are the predominance of cogwheeled smooth pursuit and the occasional observation of hypermetric saccades, both toward the side of the tumor. Patients with very large tumors finally develop a complete disruption of OKN toward the homolateral side together with concomitant gaze paralysis.
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PMID:[Oculomotor disturbances as cerebellar symptoms in pontine angle tumors. Contralateral diminution of optokinetic nystagmus as early sign of floccular lesions (author's transl)]. 30 Feb 37

Three hundred patients with intracranial hemorrhage were studied by computerized tomography (CT). Thalamic-ganglionic hematoma was found in 232; the mortality increased from 25% to 70% if ventricular extension occurred in this group. Lobar hematoma occurred in 45 of these patients, with a mortality of 20%, which was not influenced by ventricular extension. Seven had intraventricular bleeding only; of these, two died. In 12 patients with CT evidence of cisternal blood, angiography demonstrated aneurysms; the location of the blood predicted the location of the aneurysm in six. Multiple spontaneous intracerebral hematomas (ICHs) were visualized by CT in five patients. In 29 of 146 cases of ICH, postcontrast study showed enhancement; in 15, this was consistent with neoplasm, angioma, or aneurysm. In 14 with spontaneous ICH, ring enhancement occurred ten days to six weeks following hemorrhage.
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PMID:Computerized tomography in intracranial hemorrhage. 31 3

In a 18 year-old woman, an isolated benign hemangioma of the right atrium led to cardiac tamponade and acute renal failure. After 8 days of anuria, the tumor was excised and replaced by a pericardial patch. The persistence of severe renal shutdown necessitated further hemodialysis during 22 days postoperatively. The patient was discharged on the 45th day in good hemodynamic and renal condition. Thirteen cases of benign hemangioma of the heart have been reported in the literature: 12 were found at autopsy; only 4 were complicated by hemopericardium but none of these survived.
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PMID:Cardiac tamponade with renal failure due to hemangioma of the heart. 31 8


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