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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Four cases of recurrent digital fibroma of childhood are presented, bringing the total of reported cases to 79. From our material and a review of the literature, the most characteristic features of this entity are delineated. There is no predilection for either sex. Seventy-three percent (58 cases) occurred under one year of age with 14 observed at birth; only four patients were over 5-years-old and the oldest was 15. The localization is highly diagnostic, being limited to the second to fifth carpal and pedal digits and no reported involvement of thumbs or great toes. Two cases were observed in the sole and ulnar side of the hand but associated with others in classical locations. In 50% of cases, the lesions are single at the time of diagnosis. The recurrence rate, based upon cases with adequate follow-up, was found to be 75%. To our knowledge no metastasis has ever been reported. The histology is that of well-differentiated fibroblastic tumor with pathognomonic eosinophilic cytoplasmic inclusion bodies. A review of the available electron microscopic data is presented and the histogenesis is discussed.
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PMID:Recurrent digital fibroma of childhood. 74 5

A case of a peripheral odontogenic fibroma which contained aggregates of large granular cells is reported. These granular cells are similar to those previously described in the granular cell myoblastoma, congenital epulis and the granular cell ameloblastic fibroma. Deep extensions of the basal layer of overlying gingival epithelium, in double-strand fashion, are frequently observed in peripheral odontogenic fibromas. These strands closely resemble those seen in the tumor itself. On this basis, and as similar basal cell prolongations are seen in otherjaw lesions, it is postulated that residual ectomesenchymal influence may be responsible for inducing the basal cell proliferations in a similar manner to that which occurs during early embryonic dental development. This, it is suggested, might possibly be the histogenesis of the odontogenic epithelial strands in the peripheral odontogenic fibroma.
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PMID:Granular cell peripheral odontogenic fibroma. 82 26

A review of the literature has disclosed 15 cases of desmoplastic fibroma in the jaws including the present case. Fourteen out of 15 cases have affected the mandible with a female: male ratio of one to two. Ten of the reported cases were found in the first and second decades of life. Although histologically benign, the tumor usually shows locally aggressive behavior and may recur when treated conservatively. The difficulties in clinical and histological diagnosis are stressed. The paucity of reported cases prevents substantiation of guidelines for therapy.
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PMID:Desmoplastic fibroma of the jaw bones. 82 92

The clinical picture in a cyanotic newborn suggests pulmonary atresia or tricuspid atresia. Angiocardiography shows a right atrial tumor, at necropsy a ping-pong-ball sized fibroma is found. Hypoxia and congestive heart failure occurred and the baby died on his eleventh day of life. Uncertain cardiac symptomatology should always raise the suspicion of a cardiac tumor. Cardiac tumors with predominant intramural growth can show pure cardiomegaly- and/or cardiac arrhythmias, congestive failure, while intracavitary growth may lead to various kinds of in- and outflow obstruction and/or embolisations.
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PMID:[Right atrial fibroma simulating cyanotic cardiac vitium in a newborn (author's transl)]. 83 23

Three cases of myxomas of bone are presented. No similar tumor, except in bones of the jaw, was found in a study of more than 6,000 bone tumors in the files of the Mayo Clinic to Jan. 1, 1976. These three tumors were found in a series of about 5,000 lesions of bone in patients sent to the Mayo Clinic for consultation. All three of these tumors affected the femur. Care was taken to exclude lesions such as chondrosarcoma, fibrosarcoma, chondromyxoid fibroma, and ganglia of bone, all of which may contain prominently myxoid zones.
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PMID:Myxoma of bone. Report of three cases. 84 24

Angiography was done in 38 cases of pathologically-confirmed fibrous-tissue tumor. All benign fibromatous tumors and one case of desmoid fibroma were angiographically normal. A great spectrum of angioarchitecture exists in fibrosarcomas, whether they are of bone or soft-tissue origin. Heterogeneous vascularity was seen in 55% of these cases, and was related to the cell composition of the tumor. There exists a close relationship between the number of vessels in a tumor and its degree of clinical and histopathological malignancy. The most vascular part of a tumor is the least differentiated and should be used for biopsies. Angiography can be used for the grading of fibrosarcomas, and probably for assessing clinical prognosis.
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PMID:Angiographic features of fibromas and fibrosarcomas. 86 58

No class of tumor is so inadequately discussed in the otolaryngology literature as the "cementomas". Until recent years, four distinctly different benign fibro-osseouslesions containing cementum were clumped together under the heading of cementoma. The separate entities in this tumor class are benign cementoblastoma (true cementoma), cementifying fibroma, peripical cemental dysplasia, and gigantiform cementoma (florid osseous dysplasia). Only an occasional case of the gigantiform variant or an unusually aggressive cementifying fibroma requires an extensive operation for complete excision.
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PMID:Cementomas--aggressive or innocuous neoplasms? 86 70

Aggressive cemento-ossifying fibroma is the most aggressive tumor of all cementum-containing neoplasms. An extensive, destructive cemento-ossifying fibroma of the ethmoid region was found in a patient. To our knowledge, this is the first case of a cemento-ossifying fibroma in this location. A radical maxillectomy was ultimately required to control the tumor, preserving orbital contents. The unique site of origin is thought to be the result of an ectopic periodontal membrane or of a primitive mesenchymal cell rest.
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PMID:Cementomas. II. Aggressive cemento-ossifying fibroma of the ethmoid region. 86 75

A case of chondro-myxoid-fibroma, followed over 7 years, showed the following: 1. multicentric lesions, 2. new lesions in other bones developed during observation, 3. strictly extra-skeletal foci developed in subcutaneous fat. One is justified to doubt whether this tumor really is benign.
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PMID:[Multicentric chondro-myxoid-fibroma of bone with extraskeletal foci (author's transl)]. 88 22

A rare periungual tumor, clinically and histologically identical to the acquired digital fibrokeratoma, is discussed in association with the differential diagnosis of acral digital nodules. It is believed that this is the first report that conclusively links the previously described garlic-clove fibroma with the acquired digital fibrokeratoma.
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PMID:Acquired periungual fibrokeratoma. A rare benign tumor previously described as the garlic-clove fibroma. 93 97


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