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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A carcinoid tumor was discovered by chance in a 25-year-old woman with the dominant type of retinitis pigmentosa. Although a coincidental association cannot be ruled out, there is at least a possibility that the two diseases have a common embryologic origin.
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PMID:Carcinoid tumor in retinitis pigmentosa. 70 99

Adenocarcinoid is a form of appendiceal carcinoid possessing features of both carcinoid and adenocarcinoma. There are two histologic types. Thirty patients had the goblet cell type, characterized by nests of large mucin-distended cells. Nine patients had the tubular type, characterized by small glandular structures lined by uniform cells. Despite abundant mucin and a goblet cell or acinar-like arrangement, a closer relationship to carcinoid than to adenocarcinoma is suggested by a concentration of tumor elements below the crypts of Lieberkuhn, a lack of evidence of neoplastic transformation of the appendiceal mucosa, and the demonstration of argentaffin or argyrophil granules in 88% of the lesions. Six tumors, all of the goblet cell type, metastasized and resulted in the death of the patients. One of the tumours that metastasized had a prominent tubular component. Most adenocarcinoids can be adequately treated by appendectomy, but hemicolectomy is recommended for those tumors showing atypical foci, a high mitotic count, or spread beyond the appendix.
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PMID:Adenocarcinoid, a mucin-producing carcinoid tumor of the appendix: a study of 39 cases. 72 74

The angiographic features in 5 cases of carcinoid tumors of the small intestine are discussed. Findings included irregularity and narrowing of the distal mesenteric and intestinal arcade arterial branches, minimal parenchymal stain, and obstructed venous return. A stellate arterial configuration was not noted. In 2 cases in which epinephrine was employed, tumor staining of the primary lesions and their hepatic metastases was markedly enhanced. Possible mechanisms of action for the pharmacoangiographic effect of epinephrine are discussed.
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PMID:Angiographic evaluation of carcinoid tumors of the small intestine: the value of epinephrine. 80 75

Carcinoids of the testis are rare tumours developing in three different ways: 1. It may differentiate within a teratoma, 2. it may be a metastasis of a "loco alieno" seated carcubiud abd 3. it may represent a real primary carcinoid. The observation of a primary testicular carcinoid in a man aged 55 years afforded the opportunity to study such a tumor for the first time by electron microscopic and fluorescence microscopic methods. Thereby, it could bw shown, that this testicular carcinoid corresponds to the carcinoids of the lower small gut. According to the specific ultrastructure of the intracytoplasmic granules it must derive histogenetically from an EC-cell. At the moment it cannot be decided whether the primary testicular carcinoid represents an autochthonous tumor of the male gonad or solely a teratoma with one-sided differentiation in the sense of a simplified teratoma.
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PMID:A carcinoid occurring in the testis. 81 97

Eighteen cases of primary trabecular carcinoid of the ovary were analyzed from a clinicopathologic viewpoint. The patients ranged in age from 24 to 74 years and presented with symptoms of an ovarian mass; none had the carcinoid syndrome. Although the carcinoid always proved to be unilateral, the contralateral ovary was sometimes enlarged by a dermoid cyst. The carcinoid usually formed a small mass in an otherwise obvious dermoid cyst, but in six instances it formed a large, solid mass, and in 2 of these cases no other teratomatous elements could be demonstrated. The prognosis was nearly always favorable after removal of the neoplasm, although 1 patient had a recurrence after 2 years and died after 51/2 years. Primary trabecular carcinoids are characterized by a distinctive pattern of ribbons of argentaffin cells and should not be confused with a Sertoli-Leydig cell tumor, a strumal carcinoid, or a metastatic trabecular carcinoid.
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PMID:Primary trabecular carcinoid of the ovary. 83 4

The etiology of nontraumatic small bowel perforations in 24 operated patients was as follows: strangulation in five, diverticulum in four, foreign bodies in four, idiopathic in three, Crogn's disease in two, malignant atrophic papulosis of Degos (MAP) in two, and tuberculosis, carcinoid tumor, radiotherapy, and iatrogenic in one. The high mortality rate in these patients appeared to be a funciton of the disease process rather than of the means of treatment. In favorable circumstances, as in strictly localized lesions with well known etiology and otherwise normal bowel, a simple closure of perforation is warranted. In more far advanced cases operated upon early enough, we still consider bowel resection and primary anastomosis as the best method of treatment, though it yielded poor results in procedures are advisable to protect the anastomosis.
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PMID:Nontraumatic perforations of the small intestine. 83 87

Sixty-five patients seen at the Massachusetts General Hospital between 1951 and 1974 with carcinoid tumors of the gastrointestinal tract are reviewed. Sixty-two patients were operated upon, and only one carcinoid was discovered for the first time at autopsy. Although corrected actual five and ten year survival rates of more than 60% were attained, only one of 15 patients was alive five years after the discovery of liver metastases. Patients less than 60 years of age, with tumors of less than 0.5 centimeter in diameter and with no history of weight loss, survived best. Most rectal and appendiceal carcinoids were small, and there were no deaths in patients who had undergone local resection. Only 33% of the patients with small intestinal carcinoids survived for five years; none survived for more than one year after diagnosis of the carcinoid syndrome was made. All colonic carcinoids had metastasized by the time the operation was performed. Carcinoids of less than 0.5 centimeter in diameter located anywhere in the gastrointestinal tract can be managed by simple local resection. Tumors 1 centimeter in diameter warrant consideration of a more extensive operation. A radical excision usually is required for tumors of more than 2 centimeters in diameter, even in the presence of metastatic disease.
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PMID:Management of carcinoid tumors of the gastrointestinal tract. 87 42

Stimulated by a report in 1974, we have reviewed all abdominoperineal resections in a Univeristy-affiliated community hospital. From 1964--1973, 67 such procedures were performed. There were 65 adenocarcinomas, one squamous cell cancer, and one carcinoid tumor. Dukes' classification was A-4, B-22, C-39, D-4. Postoperative complications occurred in 55.1% of patients. Late complications occurred in 22% of patients. Five-year follow-up was possible in 34 patients with an overall survival of 50%.
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PMID:Abdominoperineal resection for carcinoma in the community hospital. 88 86

The authors report an analytic study of hydroelectrolytic disorders in patients with APUD tumors. In most of the cases a diarrhea occurs. The type of this diarrhea is: -- a motrice diarrhea (in the great majority of carcinoid tumor and medullary carcinoma of the thyroid); -- a secretory diarrhea (W.D.H.A.): it is the case in gastrinoma (gastric hypersecretion), in secretinoma (pancreatic hypersecretion) and in vipoma (intestinal hypersecretion). The others disorders could be no diarrhea dependant (hyponatremia by ADH hypersecretion, hypercalcemia). The personal cases of the authors are: 12 medullary carcinoma of the thyroid, 19 enteraminoma and 2 others apudomas.
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PMID:[Water and electrolytes disorders in apudocarcinomas (author's transl)]. 90 Aug 68

A case of an appendiceal carcinoid tumor with regional lymph-node metastases is presented. The size of the tumor was remarkable, as the appendix was infiltrated throughout its length. The proximal part of the appendix was intussuscepted into the cecum. Preoperatively, the lesion was diagnosed as a polypoid tumor of the cecum. A primary right hemicolectomy was carried out.
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PMID:Malignant appendiceal carcinoid with intussusception of the base manifesting as a cecal tumor: report of a case. 90 47


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