Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This typical case of alexia without agraphia, caused by an astrocytoma, is the first recorded case in the literature of alexia without agraphia with a right homonymous hemianopia caused by a tumor. This case differs from previously reported cases of the syndrome by its fluctuating clinical course and its slow progression. All but one of previously reported cases had been of vascular or surgical etiology. This course and the associated radiographic findings should differentiate the neoplastic from the vascular etiology of this most fascinating syndrome.
 ...
PMID:Alexia without agraphia. 94 97

A case is reported of a tumor composed of both oligodendrogliomatous and sarcomatous elements. The interpretation is offered that the sarcoma arose secondarily by neoplastic transformation of the hyperplastic blood vessels formed in response to the presence of the oligodendroglioma. This tumor may be considered analogous to the astrocytoma-sarcoma, which is much more common, and to the metastatic carcinoma with secondary sarcoma, of which one case has been reported.
 ...
PMID:Sarcoma arising in oligodendroglioma of the brain. 99 17

Authors report a patient with a subependymal glomerate astrocytoma in the right lateral ventricle. He maifested parkinsonian symptoms and dementia related to the preceding normal pressure hydrocephalus which was proved by an infusion test, and then advanced an akinetic mutism. Soon after a shunting operation was carried out he showed a full recovery from the symptoms, which may suggest that an incomplete block of the ventricular system is one cause of the normal pressure hydrocephalus. From pathology it was revealed that the tumor is an intraventricular astrocytoma with a fibrous stalk and was totally removed with an ease. The findings seem to accord with "Subependymal glomerate astrocytoma" (Boykin.) Further corroboration would be necessary to establish this entity.
 ...
PMID:[A case of the lateral ventricular tumor (subependymal glomerate astrocytoma) with preceding Parkinsonian symptoms due to normal pressure hydrocephalus (author's transl)]. 103 39

Two cases are reported of pupillary sparing in oculomotor palsy from temporal lobe astrocytoma. In one of them it was the first manifestation of recurrence of tumour. Tumour infiltration with resultant nerve ischemia is suggested to be the responsible pathological process.
 ...
PMID:Pupillary sparing in oculomotor palsy from temporal lobe astrocytoma. Report of two cases. 105 7

Radioisotope scanning with 99mTc-pertechnetate or 67Ga-citrate for the spinal cord tumors was reported. Six patients with spinal cord tumors including 2 ependymomas, 1 neurinoma, 1 metastatic medulloblastoma, 1 metastatic astrocytoma, and 1 metastatic pinealoma as well as 6 patients with non-neoplastic lesions were examined with this method. Two out of 6 cases with tumors showed positive scans and two equivocal scans. This new method is different from myeloscintigraphy and radioisotope angiography as already reported. It directly demonstrates tumor itself like brain scanning and is very useful as nontraumatic method for screening spinal cord lesions, especially in poor risk patient. The usefulness and limitation of this method are discussed.
 ...
PMID:Radioisotope scanning for the spinal cord tumor. 106 84

A case is reported of a neoplasm of mixed mesenchymal and neuroepithelial origin consisting of plasmacytoma, lymphoma, ganglioneuroma, and astrocytoma in the same mass. The tumour arose in the hypothalamus of a 43 year old diabetic woman who also had alpha cell hyperplasia and beta cell hypoplasia of the islets of Langerhans. It is suggested that both hypothalamic and pancreatic lesions produced diabetes mellitus in this patient.
 ...
PMID:Hypothalamic and pancreatic lesions with diabetes mellitus. 110 74

An optic nerve glioma in an 18-month-old child was examined by both light and electron microscopy. The tumor revealed the characteristic features of uniform benign and fibrillary astrocytoma. Rosenthal fibers and calcium depostis were found within numerous intracellular glial processes. The above features indicated a slow-growing tumor of long duration, confirming the generally supported assumption of the congenital nature of optic nerve glioma. One unsuspected feature was the presence of fenestrated blood vessels.
 ...
PMID:Optic nerve glioma in an 18-month-old child. 111 18

One hundred forty-seven patients with astrocytoma were treated between 1942 and 1967. There were 25 postoperative deaths. The 14 patients in whom the tumor was thought tohave been completely removed were not irradiated and all survived 5 years or longer. Seventy-one of the 108 patients with imcompletely excised lesions received radiation therapy. The 5-year survival rate for those with imcomplete resection alone was 19%, compared to 46% when irradiation was given. Based on observations up to 20 years, after incomplete removal postoperative irradiation significally prolonged useful life and may have lead to permanent control in some. There was no evidence of radiation damage. Most of these tumors were fibrillary astrocytomas, and the results apply particularly to this histologic type. Only 1 of 11 patients with gemistocytic astrocytoma survivied 5 years. The survival rate for Grade i tumors was appreciably greater than for Grade iilesions; in both grades, it was improved by irradiation.
 ...
PMID:The role of radiation therapy in the treatment of astrocytomas. 114 89

Astrocytomas are the most common intracranial neoplasm in children. It is necessary to demonstrate preoperatively the location and extent of a possible neoplastic cyst and to differentiate it from the part that is solid. This is achieved through brain scans, computer axial tomography and angiography. Though of considerable help, brain scan and computer axial tomography are insufficient in providing the neurosurgeon with the complete character and geography of the neoplasm necessary for successful surgical treatment. Demonstration of these features can only be elucidated by contrast angiography. Consequently, the coordination of these three techniques permits the precise evaluation of the presence, nature, and operative and postoperative course of cystic astrocytomas.
 ...
PMID:Coordinated investigation of cystic astrocytomas by nuclear medicine and neuroradiological techniques. 117 36

A combination of linoleic and linolenic acids has been shown to be able to partly replace serum in maintaining cell division of neural tumor lines. Addition of essential fatty acids to C-6 rat astrocytoma cells grown in serum-deprived medium increased the rate of cell proliferation and restored morphological appearance. Essential fatty acids also restored the rate of 3H-thymidine uptake by N-18 neuroblastoma cells grown in a serum-deprived medium. In the complete absence of serum, neuroblastoma cells were unable to proliferate despite addition of essential fatty acids. These studies indicate the importance of essential fatty acids in controlling the rate of neural tumor proliferation.
 ...
PMID:Effect of essential fatty acids on proliferation of two neural tumor lines. 117 7


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>