Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

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Human Gene/Protein
C12orf59 8.3
KIAA1522 protein 8.3
INPP5A protein 8.3
deleted in lung and esophageal cancer protein 1 8.3
mitochondrial translation optimization 1 homolog 8.3
Acyl-CoA thioesterase 8 8.3
GABPB2 8.3
skin-specific protein 8.3
GTP binding protein 4 8.3
CCDC121 8.3
KRTAP5-7 8.3
PDGFB protein 8.3
C1orf142 8.3
PCDH9 protein 8.3
PCDHGA2 8.3
Ring finger protein 38 8.3
DACH2 protein 8.3
ZC3H7A 8.3
CNIH4 8.3
retinoic acid receptor beta 5 8.3
SNRNP48 8.3
importin alpha-3 8.3
FAM39B 8.3
RNPL 8.3
abhydrolase domain containing 14B 8.3
Cytoplasmic FMR1 interacting protein 1 8.3
TENSIN 8.3
MCT 6 8.3
TRAF3IP3 protein 8.3
fls485 8.3
VICKZ2 8.3
ADAM metallopeptidase domain 29 8.3
ZNF781 8.3
RAB5A protein 8.3
OTUD6A 8.3
PAX interacting protein 1 8.3
Ubiquitin carboxyl-terminal hydrolase 47 8.3
MUM-2 7.7
NLVCF 7.7
LRRC2 7.3
cholinergic receptor, muscarinic 1 7.3
Transmembrane protein 139 7.3
TIMM17A 7.3
DERL1 7.3
TRY6 7.3
FIBCD1 protein 7.3
NEL-like 1 7.3
transient receptor potential channel 7 7.3
CC2D2B 7.3
dishevelled 3 7.3
Sec23 homolog B 7.3
ubiquitin specific protease 19 7.3
TSPAN-2 7.3
transmembrane protein 79 7.3
Smoothened homolog 7.3
TRMT11 7.3
mucin 1, cell surface associated 7.3
SFTPG 7.3
LOXL4 protein 7.3
HIST1H2AE 7.3
C3orf62 7.3
KRTHB1 7.3
HIST1H3D 7.3
SRGAP2 protein 7.3
NBPF9 7.3
ubiquitin associated protein 2 7.3
angiopoietin-related protein-2 7.3
RNA binding motif protein 47 7.3
KIAA0554 7.3
P2RY10 7.3
ASAP1 protein 7.3
kinesin family member 26B 7.3
dedicator of cytokinesis 10 7.3
C3orf35 7.3
MRCL 7.3
SCAP2 7.3
IRX3 protein 7.3
CYTH3 7.3
FRMPD1 7.3
KIAA1026 7.3
more...
Disease
Thyroid Lymphoma 8.3
Lucke renal adenocarcinoma 8.3
Hodgkin's disease nodular sclerosis type 8.3
radiation related cancer 8.3
Meningeal melanomatosis 8.3
Adult dermatomyositis 8.3
Chest wall mass 8.3
Sclerosis of the skin 8.3
metastatic adult soft tissue sarcoma 8.3
Local tumor spread 8.3
metastases 8.3
localized PNET 8.3
Perineal infection 8.3
Stage IV Prostate Adenocarcinoma 8.3
meningioma; transitional 8.3
Vertebral wedging 8.3
Haemangioblastomatosis 8.3
Mixed Mesodermal Tumor 8.3
Papillary carcinoma, diffuse sclerosing 8.3
Thyroid Lymphoma 8.3
Apocrine breast carcinoma 8.3
stage IV anal cancer 8.3
Adhesion of lung 8.3
Adrenal Cortical Carcinoma 8.3
Metastasis to orbit 8.3
Metastases to neck 8.3
Soft Tissue and Bone Tumor 8.3
Parasympathetic paraganglioma 8.3
Malignant esophageal stricture 8.3
Carcinoma in a polyp 8.3
Sarcomatous malignant mesothelioma 8.3
Malignant gastrointestinal tract tumors 8.3
Malignant Mixed Mesodermal Tumor 8.3
Hereditary Paraganglioma 8.3
Laryngeal Leiomyosarcoma 8.3
Metastases to stomach 8.3
Thoracic neuroblastoma 8.3
Appendiceal Adenocarcinoma 8.3
Ectopic hyperthyroidism 8.3
Oesophageal adenocarcinoma metastatic 8.3
rectosigmoid growth 8.3
Secondary systemic vasculitis 8.3
thyroid cancer stage 8.3
Crystal synovitis 8.3
Necrotizing granulomatous lymphadenitis 8.3
Primitive polar spongioblastoma 8.3
Gallbladder Carcinoma 8.3
scirrhous carcinoma of the rectum 8.3
Epithelioid Trophoblastic Tumor 8.3
Metastasis to spleen 8.3
Lymphoma, metastatic 8.3
stage III carcinoma of the prostate 8.3
Penile neoplasms 8.3
adenosquamous cell lung cancer 8.3
Papillary Thyroid Microcarcinoma 8.3
blastema predominant Wilms' tumor 8.3
Metastases to soft tissue 8.3
Aplastic marrow 8.3
Thyroid cancer metastatic 8.3
Adnexal tumor 8.3
Disseminated adenocarcinoma 8.3
Desmoplastic Melanoma 8.3
Sebaceous epithelioma 8.3
Metastasis to small intestine 8.3
neuroepithelial tumor of the kidney 8.3
Peritoneal metastases 7.9
Adenosquamous cell carcinoma 7.9
Spinal metastases 7.9
Metastasis to thyroid 7.8
renal cell carcinoma stage 7.8
Metastasis to heart 7.8
Renal metastasis 7.7
Breast metastases 7.7
Skin deposits 7.7
Metastatic renal carcinoma 7.7
Cardiac neoplasms 7.7
Epidural tumor 7.7
Adrenal metastases 7.6
Ovarian metastasis 7.6
Axillary metastases 7.6
more...
Symptom
Vesical tenesmus 8.3
Pain from metastases 8.3
Sister Mary Joseph's nodule 6.6
Painless hematuria 6.3
Metastatic bone pain 5.9
Auspitz's sign 5.9
rib pain 5.8
Chest wall pain 5.7
Paroxysmal hypertension 5.6
Inspiratory stridor 5.5
Gastrointestinal signs and symptoms 5.5
increased abdominal size 5.5
Hemorrhagic ascites 5.3
Bloody discharge 5.3
Flu-like symptoms 5.3
bone pain 5.2
SLE-like symptoms 5.1
Acute back pain 5.1
penile lesion 5.1
glossopyrosis 4.9
Chills and fever 4.9
unable to sleep 4.7
Deep pain 4.7
Radiating pain 4.7
lump in the neck 4.6
peau d'orange 4.6
Local swelling 4.6
Massive edema 4.4
Neurogenic pain 4.4
febricula 4.4
abdominal fullness 4.3
Foot pain 4.3
vaginal pain 4.3
swollen scrotum 4.2
axillary pain 4.1
Limb weakness 4.1
anal pain 4.1
dysorexia 3.9
Upper abdominal pain 3.9
left lower quadrant pain 3.9
Cullen's sign 3.9
Somatic pain 3.9
Bloody nipple discharge 3.9
Radicular pain 3.8
skin impairment 3.8
Generalized pruritus 3.7
tenesmus 3.7
Portal venous gas 3.7
flank pain 3.7
nipple discharge 3.6
testicular pain 3.6
Cramping 3.6
Cancer Fatigue 3.6
Pneumobilia 3.6
Osler's nodes 3.6
prostatism 3.5
nipple discharge 3.5
epigastric pain 3.5
thoracic back pain 3.5
McBurney's point 3.5
cold sweats 3.5
Severe diarrhea 3.5
lumbar back pain 3.4
abdominal discomfort 3.4
testicular lump 3.4
mouth pain 3.4
neurological pain 3.4
Murphy's sign 3.3
Cushingoid 3.3
right upper quadrant pain 3.3
Cushingoid 3.3
generalized abdominal pain 3.2
cancer pain 3.2
leg edema 3.2
Intractable pain 3.2
Pain and tenderness 3.2
intestinal angina 3.2
Watery diarrhea 3.2
frequent urination 3.2
breast hyperplasia 3.1
more...
Drug
Sodium phosphate P 32 8.3
Imidazole Carboxamide 7.3
Drostanolone 7.3
Blutal 7.3
Boniva 7.3
OncoScint CR/OV 7.3
OncoScint 6.9
Zeniplatin 6.9
Prostascint 6.7
ProstaScint 6.6
Isosulfan blue 6.6
Quadramet 6.6
CEA-Scan 6.5
Thyrogen 6.4
Fotemustine 6.3
Tilomisole 6.3
Rubitecan 6.3
Iotasul 6.1
Aredia 6.0
Depreotide 5.9
Iii 5.9
Mifamurtide 5.9
Motexafin lutetium 5.9
Fareston 5.8
Ferumoxtran-10 5.8
Proleukin 5.8
Fareston 5.8
OctreoScan 5.6
Tetrofosmin 5.5
Talabostat 5.5
Acino 5.5
Methotrexate sodium 5.5
Edatrexate 5.5
Paraplatin 5.3
Mangafodipir trisodium 5.3
Smancs 5.3
Arresten 5.3
Leucovorin 5.2
Uzel 5.1
Femara 5.1
Eulexin 5.1
Eniluracil 5.1
Eniluracil 5.1
18DG 5.1
Epidoxorubicin 5.1
MTC 5.0
Xeloda 5.0
Estracyt 5.0
Estracyt 4.9
Torisel 4.9
Fadrozole hydrochloride 4.9
Oncaspar 4.9
Zanolimumab 4.9
CDX 4.8
Isovorin 4.8
Aromasin 4.8
Pertuzumab 4.8
Zoledronic acid 4.8
CPT-11 4.8
Diastase 4.8
Bleomycins 4.8
Etidronate disodium 4.7
Marimastat 4.7
Clodronate 4.7
Zoladex 4.6
Gd-BOPTA 4.6
Thyroglobulin 4.6
Lipiodol 4.6
Ormaplatin 4.6
Ilmofosine 4.6
Emcyt 4.6
Semaxanib 4.6
Cetuximab 4.5
Batimastat 4.5
Batimastat 4.5
Nexavar 4.5
Oxaliplatin 4.5
Gemzar 4.5
Vandetanib 4.5
Zoladex 4.5
more...
Enzyme
3-KSR 6.7
galactose-6-sulfatase 5.9
prostate-specific membrane antigen 5.5
prostate-specific antigen 4.9
cathepsin O 4.7
stromelysin-3 4.7
GalT-4 4.5
kallikrein 10 4.5
cathepsin B-like protease 4.5
matrix metalloproteinase 2 4.3
matrix metalloproteinase 10 4.1
MDP 4.1
cancer procoagulant 4.0
ADP-ribosylarginine hydrolase 4.0
matrix metalloproteinase 14 3.8
matrix metalloproteinase 9 3.7
PNAE 3.7
STK11 3.6
8-lipoxygenase 3.5
sarcosine dehydrogenase 3.5
alpha-methylacyl-CoA racemase 3.4
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.4
urokinase-type plasminogen activator 3.4
macrophage elastase 3.4
hepsin 3.4
hepsin 3.4
TACE 3.4
dihydropyrimidine dehydrogenase 3.3
dihydropyrimidine dehydrogenase 3.3
cytosine deaminase 3.3
N-acetylglucosaminyltransferase V 3.3
histone-lysine N-methyltransferase 3.3
coagulation factor VIIa 3.2
ALDH 3.2
MHCK 3.2
MMP 3.2
ERK 3.1
lysyl oxidase 3.1
nepenthesin 3.0
isochorismatase 3.0
aspartyl aminopeptidase 3.0
mannosylphosphoryldolichol synthase 3.0
fucokinase 2.9
thymidine phosphorylase 2.9
STK4 2.8
HDR 2.8
CAO 2.8
enolase 2.8
cholesterol 25-hydroxylase 2.8
interstitial collagenase 2.8
RGP 2.8
methylthioadenosine phosphorylase 2.7
legumain 2.7
dihydroxyacetone-phosphate acyltransferase 2.6
MAT 2.6
cathepsin K 2.5
cathepsin D 2.5
KLK13 2.5
NMT 2.5
FTR 2.5
sialyltransferase 2.4
cathepsin B 2.4
thymidylate synthase 2.4
sialyltransferase 2.4
sialyltransferase 2.4
DCF 2.4
MAT 2.4
MMP-3 2.4
LGT 2.4
MSAS 2.4
phosphoinositide 5-phosphatase 2.4
DSR 2.4
carboxypeptidase G2 2.3
MetE 2.3
CLK1 2.3
matriptase 2.3
glycoprotease 2.3
collagenase 3 2.3
HOA 2.2
CPL 2.2
more...
Compound
tetrahydro-4H-thiopyran-4-one 1,1-dioxide 8.3
Luvatren 7.3
N-Nitroso-N-butylurea 7.3
NSC 337766 6.7
Primobolan Depot 6.7
Drostanolone 6.7
Pyrazine diazohydroxide 6.5
1-Methylinosine 6.3
Tetrahydrocortisol 6.1
4,4'-Dihydroxybenzophenone 6.1
Toxol 5.9
Copper 8-hydroxyquinoline 5.9
Pyrazine diazohydroxide 5.8
C15H15NO2 5.7
5-Chlorouracil 5.7
cyclopentanone oxime 5.7
FUDR 5.5
4-iodobenzamide 5.5
GANU 5.5
Dioxadet 5.5
DNPC 5.5
5H-benzo[a]phenothiazine 5.5
BEP 5.4
RPCNU 5.3
Diethylstilbestrol diphosphate 5.3
DHAC 5.3
1,2,4,5-benzenetetramine 5.3
R 7000 5.3
1-pyrrolidinecarbodithioic acid 5.3
TNM 5.2
GANU 5.1
12H-benzo[a]phenothiazine 5.1
4-methyl-1,3-thiazole 5.1
Acronycine 5.1
Leucovorin 5.1
Pimonidazole 5.1
Pimonidazole 5.1
Estracyt 5.0
Estracyt 5.0
MTC 4.9
Pleuromutilin 4.9
Chlormerodrin 4.9
Lycurim 4.9
Nomilin 4.9
Thaliblastine 4.9
DAVA 4.9
Cirsiliol 4.9
2-iodobenzamide 4.9
Capecitabine 4.9
folinic acid 4.9
AFU 4.8
DMNM 4.8
BW 301U 4.8
o,p'-DDD 4.8
ICRF 159 4.8
CPT-11 4.8
5-FU 4.8
ICRF 159 4.7
ICRF 159 4.7
Exemestane 4.7
Sarcophine 4.7
Jatrophone 4.7
Patent blue 4.7
Velban 4.7
ENNG 4.6
Rocaglamide 4.6
RFCNU 4.6
Bicalutamide 4.5
Tegafur 4.5
FUMP 4.5
Epirubicin 4.4
DIC 4.4
Ifosfamide 4.4
Digitoxigenin 4.4
2,6-piperazinedione 4.4
I-123 BMIPP 4.4
EHDP 4.3
Anastrozole 4.3
Tegafur 4.3
Neuraminic acid 4.3
more...