Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027627 (metastases)
103,950 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 6290
nodal 4156
Mol 2530
MRI 1835
p53 1812
She 1548
osteosarcoma 1352
FDG 1218
epidermal growth factor receptor 1097
TNM 979
HER2 977
E-cadherin 972
vimentin 952
estrogen receptor 943
carcinoembryonic antigen 905
vascular endothelial growth factor 884
cytokine 875
collagen 873
tyrosine kinase 798
cytokeratin 776
Ki-67 714
BRAF 702
CEA 695
prostate-specific antigen 689
somatostatin 674
interferon 652
thyroglobulin 636
rhabdomyosarcoma 593
CD8 569
interleukin-2 557
progesterone receptor 540
EGFR 536
cage 533
matrix metalloproteinase 529
alkaline phosphatase 512
CD44 511
Pol 500
colon carcinoma 499
fibronectin 484
lymphoid 468
more...
Disease
metastases 103950
tumor 46273
cancer 42306
carcinoma 15367
breast cancer 10569
melanoma 8299
primary tumor 7239
adenocarcinoma 6206
prostate cancer 4693
colorectal cancer 4055
lung cancer 3570
squamous cell carcinoma 3566
liver metastases 3433
tumor growth 3340
tumor progression 3138
renal cell carcinoma 3027
sarcoma 2469
bone metastases 2424
lung metastases 2390
gastric cancer 2107
hepatocellular carcinoma 2053
lung carcinoma 1736
brain metastases 1683
osteosarcoma 1656
colon cancer 1619
metastatic breast cancer 1588
tumorigenesis 1379
non-small cell lung cancer 1376
lymphoma 1325
pancreatic cancer 1268
thyroid cancer 1250
carcinogenesis 1246
metastatic melanoma 1235
carcinoid 1190
Melanoma 1122
ovarian cancer 1087
aggressiveness 920
residual disease 855
neuroblastoma 854
rectal cancer 831
more...
Symptom
pain 2896
abdominal pain 694
diarrhea 583
dyspnea 461
nausea 456
vomiting 447
headache 442
fatigue 419
bone pain 383
anesthesia 372
weakness 323
back pain 319
cough 308
anorexia 304
nausea and vomiting 214
chest pain 182
seizures 180
discomfort 176
discomfort 171
hemoptysis 163
cachexia 134
epigastric pain 130
low back pain 117
ENT 110
collapse 109
shortness of breath 108
hepatomegaly 104
Ill 104
analgesia 103
erythema 103
cancer pain 94
flank pain 91
constipation 89
numbness 82
flushing 82
hoarseness 78
respiratory distress 78
paresthesia 74
splenomegaly 72
dizziness 70
more...
Drug
Dermatol 1074
Cardiovasc 530
IL-2 361
CSF 272
Adriamycin 267
IFN-gamma 214
ENT 191
CPT-11 169
CTX 159
Herceptin 153
HCG 144
Paraffin 117
Docetaxel 110
lysine 109
Bevacizumab 99
uPA 99
Taxol 97
PTC 87
Imatinib 86
CAM 86
MAP 82
ROC 81
Leaf 78
Cetuximab 73
Oxaliplatin 69
Lipiodol 64
Leucovorin 59
Sorafenib 57
Zoledronic acid 57
Irinotecan 57
PTH 52
MTC 52
G-CSF 52
ADM 52
Monit 51
ABC 51
Gleevec 48
ROS 48
CTC 46
ETS 45
more...
Enzyme
ERK 2746
mitogen-activated protein kinase 668
prostate-specific antigen 665
focal adhesion kinase 528
alkaline phosphatase 512
urokinase-type plasminogen activator 372
luciferase 361
prostate-specific membrane antigen 264
lactate dehydrogenase 261
reverse transcriptase 261
protein kinase 250
MEK 249
collagenase 196
acid phosphatase 186
matrix metalloproteinase 2 153
MDP 152
peroxidase 147
CD10 144
APC 137
protein kinase C 130
caspase-3 127
MMP 124
tyrosinase 122
trypsin 104
thrombin 97
matrix metalloproteinase 9 95
plasmin 94
PARP 93
proteasome 90
gamma-glutamyl transpeptidase 89
thymidine kinase 87
ACS 86
catalase 86
P-glycoprotein 84
enolase 83
phosphatidylinositol 3-kinase 81
cathepsin D 77
cathepsin B 73
alanine aminotransferase 71
topoisomerase 66
more...
Compound
Clin 10435
Dec 7224
DNA 3368
TNM 979
MDA 918
iodine 863
calcium 696
5-FU 624
oxygen 552
glucose 526
tyrosine 490
water 409
acetate 383
Thyroid 374
methionine 346
Adriamycin 344
His 299
fluorine 279
phosphate 272
sodium 271
galactose 259
DDP 246
nitric oxide 228
iron 217
TSH 215
sulfate 193
serine 192
MEK 191
DTPA 191
DIC 181
TNF 177
arginine 171
folinic acid 169
CPT-11 167
MTT 167
creatinine 165
BCG 164
Optimal 162
barium 162
CTX 159
more...