Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027627 (
metastases
)
103,950
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In this study a state of temporary defibrinogenation was induced in rats by
Defibrase
treatment. It was found that the formation of pulmonary
metastases
after intravenous tumour cell injection was decreased in defibrinogenated rats. However, defibrinogenation did not influence the effect of trauma and infusion of dextran 1000 on metastasis formation. Both these procedures stimulated the formation of
metastases
in defibrinogenated rats. These results indicate, that fibrinogen and/or fibrin are of importance for the formation of
metastases
but that the stimulating effect of trauma and dextran 1000 on metastasis formation is independent of fibrinogen and/or fibrin.
...
PMID:Pulmonary metastasis formation after intravenous tumour cell injection in defibrinogenated rats. 12 72
