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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Breast cancer accounts for about 5-8% of cancer in India. It is second to cancer of the cervix in order of frequency. Parsee women have a higher incidence of breast cancer than Hindu women. The unmarried, lately married, and nullipara women are at higher risk than early married and multiparous women. Sometimes cancer affects women of the same family. Women with family histories of cancer should not use estrogen. 50-70% of all breast cancers, when detected, are in their later stages when the chances of a cure are practically nonexistent. 20% of breast cancer patients may live up to 5 years with the disease without receiving treatment. Following radical treatment of curable cases, metastases can remain dormant for many years, up to 18-20, before it develops. Management of breast cancer is biologically, immunologically, and histologically heterogeneous in character and requires multidisciplinary treatment: surgery, radiotherapy, hormone, chemotherapy, and immunotherapy. About 20-40% of late stage cases respond to hormones. Metastatic bone pain is alleviated by local radiotherapy. The management of breast cancer is a controversial topic including such questions as the value of postoperative radiotherapy following radical mastectomy; prophylactic versus therapeutic oopherectomy, and the place of adjuvant chemotherapy.
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PMID:Problems and prospects of cancer of the breast in India. 50 Nov 20