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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hemangiopericytoma is a vascular tumor originating from the pericytes which surround the capillaries. The tumor occurs anywhere in the body preferably at head and neck and the extremities. In less than 3% it grows in the stomach. In spite of surgical excision local recurrence or hematogene metastases must be expected. We report a case of primary hemangiopericytoma of the stomach which could only be diagnosed by metachrone liver metastases. This case shows that hemangiopericytomas and their metastases belong to the differential diagnosis of cystic liver lesions. Diagnostic procedure, therapy and prognosis of this rare tumor is discussed by an analysis of the literature.
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PMID:[Metastatic hemangiopericytoma of the stomach. Case report and review of the literature]. 148 53

Hemangiopericytoma, an uncommon neoplasm derived from pericytes, occurs in many locations throughout the body. The clinical course of this tumor is variable with the most malignant lesions capable of producing metastases. This report describes 5 patients who had hemangiopericytoma of the breast. All were women between 47 and 57 yr old. The tumors varied from 3.2 to 19 cm (average, 9 cm). Three were treated by mastectomy and two by local excision. All remained disease free for a median duration of 22 mo and for an average of 46 mo (3 to 144 mo). We have found eight additional already published examples of mammary hemangiopericytoma in adult women ranging in age from 33 to 67 yr (average, 51 yr). The tumors averaged 6 cm (1 to 29 cm) in diameter. Three were treated by mastectomy and 5 by excision. All 8 patients remained disease free at last follow-up, averaging 84 mo (16 to 276 mo). Thus, it appears that hemangiopericytoma arising in the breast is a clinically low-grade form of sarcoma regardless of tumor size. Whenever possible, initial treatment should be complete local excision with breast preservation. Total mastectomy may be necessary for exceptionally large lesions.
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PMID:Hemangiopericytoma of the breast. 323 97

Hemangiopericytoma, an unpredictable tumour, is not rare in the buccal cavity. Nine cases, most of which have been followed-up over a long period, show that, in this localisation, this neoplasm shows the unpredictable nature, though to a lesser degree (recurrences and metastases) of those situated in other parts of the body. Histological and ultrastructural analysis shows, apart from its characteristic perivascular features, much cellular polymorphism responsible for the diagnostic problems. A variety of cells, endothelial, fibroblastic and smooth muscle are observed next to the pericytes. The predominance of one or another cell type significantly affect the prognosis; immature forms with an endothelial predominance have a recurrent course, whilst fibrous forms have a much better prognosis. This diversity tends to support the histogenetic concept of one blastomatous cell responsible for the variable maturative possibilities.
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PMID:[Hemangiopericytomas of the buccal cavity. Anatomoclinal and ultrastructural study. 9 cases]. 685 33

Hemangiopericytomas are soft tissue sarcomas of vascular origin consisting of pericytes. 484 cases from the literature and 6 from the University Surgical Clinic, Cologne, were studied with regard to age, sex, organ distribution, symptoms and course of disease. The age ranged from 3.5 to 92 years, with a peak in the fifth and sixth decades. Females predominated only slightly. Hemangiopericytomas were most common in the extremities (35%). The symptoms were not characteristic. A painless mass was the first symptom in 60% of patients. The frequency of recurrence was high (32%) and metastases developed in 39% of patients. Wide local excision is the treatment of choice. Hemangiopericytoma appears to be a radioresistant neoplasm, nor is there evidence that chemotherapy is a useful adjunct in its treatment.
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PMID:[Clinical aspects and therapy of hemangiopericytoma]. 722 14

Hemangiopericytoma (HP) is extremely rare in our country. During the last 30 years only two cases were found in the material of our institute. The first case was a tumor of the neck. In spite of little histological evidence of malignancy, local recurrence together with bone metastases occurred four years after removal of the primary tumor. The second case might be a transition of a HP into a hemangioendothelioma. The primary tumor at the lower arm showed the histological pattern of a HP but contained some capillaries with suspicious endothelial proliferations. A nodule in the axilla revealed the pattern of hemangioendothelioma with some areas which resembled a HP. The visceral metastases contained tumor tissue with the typical appearance of hemangioendothelioma. Evaluation of dignity of hemangiopericytomas is extremely difficult. Differentiation of malignant cases of HP from other richly vascularized soft tissue sarcomas and especially from stromal sarcoma of uterus may present problems.
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PMID:[Hemangiopericytoma (author's transl)]. 726 28

Hemangiopericytoma is a rare tumor of vascular origin. This tumor has a malignant potential and often recurs or metastasize. A case of primary pulmonary hemangiopericytoma which recurred locally 10 years after the first surgery is presented. The histological appearance of the tumor had some findings of malignant potential in both of the primary and recurrent lesions. We discussed on malignant potential of this tumor in the number of mitotic figures, cellular atipia, and DNA ploidy pattern.
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PMID:[A case of primary pulmonary hemangiopericytoma recurred locally 10 years after the first surgery]. 756 29

Hemangiopericytoma is an uncommon vascular tumor with variable malignant potential. The origin, structure and function of pericytes remains controversial. Intra-abdominal hemangiopericytomas are highly aggressive soft tissue tumors with a great propensity for malignant transformation. We report on a case of hemangiopericytoma of the pancreas in a 53-year-old female presenting with abdominal pain. Ultrasonography and CT scan revealed a cystic tumor of the head of the pancreas. The patient underwent successful pancreaticoduodenal resection and is alive with no signs of recurrence 25 months following surgery. Ultrastructural studies are necessary to differentiate hemangiopericytomas from other sarcomas. Malignancy may be ascertained only in the presence of metastases or local recurrence. Routine surveillance is advocated.
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PMID:Hemangiopericytoma of the pancreas: report of a case and review of the literature. 767 67

Hemangiopericytomas are rare tumors of the head and neck. The benign presentation of this tumor belies its high local recurrence rate, local aggressiveness, and malignant potential. In view of these characteristics, workup to provide a diagnosis preoperatively is of significant importance. Diagnostic imaging is helpful in planning operative management, detecting metastases, and narrowing the list of differential diagnoses. However, because of the variety and lack of specificity of radiologic findings, it is generally difficult to provide a diagnosis. A history of a painless, slowly growing, otherwise asymptomatic mass, together with the radiologic findings of a vascular neoplasm, should enhance the suspicion of an HPC as a diagnosis. Hemangiopericytoma should be included in the differential diagnosis of any vascular soft tissue lesion presenting in the head and neck, and plans for surgical intervention should include the possibility of aggressive, wide local resection in order to adequately treat such a lesion should it be encountered.
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PMID:Hemangiopericytoma of the masticator space. 865 39

Hemangiopericytoma is a mesenchymal neoplasma, originated from pericytes---a cell type surrounding capillaries. Primary localization in the lung is especially rare. We report two cases of hemangiopericytoma of the lung with a completely different clinical outcome: one patient with an asymptomatic, peripheral lung tumor, 18 months disease-free after radical surgical therapy and another one with an advanced lung tumor, that infiltrated the pulmonary artery and caused distant pulmonary metastases. Based on the case report, possibilities and difficulties in the diagnosis as well as therapy of this rare primary pulmonary tumor are discussed.
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PMID:[Hemangiopericytoma--rare lung tumor]. 875 67

Hemangiopericytoma is a rare tumor that originates from the pericytes. Only histology permits a reliable diagnosis. There are no known parameters to predict the biological behavior of the tumor, so every hemangiopericytoma has to be treated as potentially malignant. No age or gender prevalence of this tumor in the region of the head neck has yet been observed. Hemangiopericytoma should be treated by radical surgery; chemotherapy or radiation should be reserved for incompletely removed or metastatic tumors. Metastasis and recurrences have been described even decades after first tumor treatment, so that all patients should undergo life-long follow-up. As an example for a fulminant course of a malignant hemangiopericytoma (G3) we present the case of a 24-year-old female patient who initially presented nonspecific symptoms, was diagnosed late, and eventually died of her tumor despite chemotherapy and surgical treatment.
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PMID:[Aggressive growth of hemangiopericytoma in the area of the facial skull]. 941 Jun 28


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