Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Patients after operative and/or radiological therapy for cervical cancer should have gynecological follow-up examinations every two months in the first year. In cases of urological complications after irradiation therapy, radionephrography, infusion urogram, blood count, cystoscopy, and cystometry should also be carried out after two months. Depending on the clinical picture, radionephrography, blood count and urinalysis are to be repeated in regular intervals. After lymphography with positive findings, x-ray controls are necessary after two and four months. In cases of increasing hydronephrosis and hydroureter due to fibrostenosis of the ureter plastic surgery is recommended. Most urological complications are to be expected after radical operation and postoperative irradiation. In patients with endometrial uterine cancer, metastases mostly occur paraurethrally and in the lungs. Chest x-ray is to be taken every six months. Suspicious paraurethral hardening is cytologically diagnosed by needle biopsy. In ovarian carcinoma stage III and IV repeated x-ray controls of the lungs during longterm polychemotherapy are advisable. Prior to second look operations after combined treatment a second look laparoscopy is particularly important. Urological complications are more frequent after therapy of cervical cancer while ovarian carcinoma is more likely to develop complications of the small bowel.
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PMID:[Clinical and urological after care in gynecologic neoplasms]. 21 74

Carcinoma metastatic to the ureter is uncommon, only 160 patients having been reported upon to date. During a ten year period, 82 patients with ureteral obstruction, secondary to metastatic disease, were seen at the UCLA Hospital. A critical analysis of the records of these patients revealed important clinical and diagnostic criteria to aid in the evaluation and treatment of extrinsic ureteral obstruction. Tumors of the cervix, prostate, breast and colon-rectum were the most common primary lesions to metastasize to the ureter. Subtle changes in urinary symptoms or in laboratory values should alert the physician to the possibility of ureteral involvement. Early detection of metastatic ureteral obstruction prior to the ravages of uremia may allow time for more aggressive use of adjuvant therapeutic modalities that would, at a later stage of the disease, be ineffectual or contraindicated.
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PMID:Ureteral obstruction secondary to metastatic tumors. 41 34

A case is reported, the 33rd to be published in the literature, of malignant retroperitoneal xanthogranuloma. The tumor involved 2 cm of the right ureter at the junction between the middle and upper thirds. The middle third of the ureter was removed and ureteral continuity established by end to end ureteral anastomosis. The patient died fourteen months later probably from metastases, though the presence of these was not confirmed.
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PMID:[Retroperitoneal malignant xanthogranuloma. 1 case and a literature review]. 49 Jul 69

Metastasis to the ureter may evolve by direct or indirect extension and invasion from the most common malignant tumors, such as breast, colon and lymphoma. A case of an unusual extension of metastatic infiltration to the ureter, kidney and other intra-abdominal and retroperitoneal structures is reported. Such a case has not been presented roentgenographically in the urologic or radiologic literature.
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PMID:Metastatic cancer to the ureter and kidney from malignant lymphoma. A review of the literature. 57 32

The authors report two new observations of ureteral metastases from prostatic cancers and review the 17 already published cases. The relative rarity might well be only apparent, in relation with the delay in the exploration of the first observations. The diagnostic criteria are less clinical and radiological than anatomo-pathological, the metastases contrasting themselves with ureteral invasion by direct propagation. The anatomical status shows no predominance between tumoral or infiltrating forms, nor of any particular site on the ureter, while noting a relative frequence of bilateral involvement. The therapeutic approach is dependant upon these factors. The prognostic is reserved, at the cost of a segmental ureteral resection or a nephro-ureterectomy.
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PMID:[Ureteral metastases from prostatic cancers. 2 cases. Review of the literature]. 74 53

A female patient is described with multiple papillary transitional cell tumours involving left renal pelvis, left ureter, bladder and urethra with metastases to uterine cervix, uterine cavity and left ovary with cyst formation. The surgical management and possible explanations of the pathogenesis are discussed.
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PMID:Multiple urothelial tumours with metastases to uterus and left ovary. A case report. 84 13

The propensity of a hypernephroma to invade the renal vein and even the inferior vena cava is widely known. However, in contrast to papillary carcinoma of the kidney, hypernephromas rarely involve the ureter. Review of the English literature reveals 42 reported cases of ureteral involvement. Most represented metastases as opposed to direct, contiguous extension which is extremely rare. C case of hypernephroma with contiguous castlike extension into the ureter without mucosal violation is presented. Mechanisms of ureteral involvement and implications regarding treatment of hypernephromas are discussed.
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PMID:Hypernephroma and associated ureteral involvement. 99 52

The oral administration of N-bis(2-hydroxypropyl)nitrosamine (DHPN) in drinking water induced lung tumors in high incidence in rats at 25 weeks. Histologically, they were adenoma, adenocarcinoma, squamous cell carcinoma, and combined squamous cell and adenocarcinoma. Metastases of adenocarcinoma were observed in regional lymph nodes. The development of tumors in other sites was seen in the liver, thyroid, kidney, ureter, urinary bladder, and pancreas. The incidence of lung tumor was distinctly higher than that of other sites. These results indicate that the target organ of DHPN was the lung and that oral administration of this chemical carcinogen was responsible for the development of lung carcinomas in rats.
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PMID:Lung carcinomas induced by oral administration of N-bis(2-hydroxypropyl)nitrosamine in rats. 102 5

Fourty-one patients with primary invasive carcinomas of the ureter were seen at Memorial Hospital from 1947 to 1972. Overall survuval patterns were similiar in 19 patients with and 22 patients without prior or concomitant urothelial cancers elsewhere in the urinary tract, with 5-year survival rates, as estimated by the product-limit methos, of41% for both groups. Prognosis was determined primarily by anatomical stage of ureteral cancer. In 11 Stage A (submucosal) patients, 7 Stage B (muscular), 12 Stage C (periureteric fat), and 9Stage D (extraureteral), the similarly estimated 5-year survival rates were 91%, 43%, 23%, and nil, respectively. None of Stage A cases had metastases for periods ranging from 5 to 11 years after surgery alone. Seventy-eight percent of patients with more advanced stages died within 3 years of treatment, withmetastases mainly in pelvic and para-aortic lymph nodes.
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PMID:Primary carcinoma of the ureter: a prognostic study. 114 96

The case of a patient with cancer of the sigmoid is presented. Thanks to surgical procedures, radiological treatment and chemotherapy, his life was prolonged by 8 years. It is worth noting that the original tumour gave later distant metastases to the ureter, right kidney, bladder, intestines and lymph nodes.
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PMID:Contribution to the evaluation of operability limits of tumours. 123 31


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