Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors report a case of gastric epithelial leiomyoma. (Leiomyoblastoma). Macroscopically, such tumors resemble leiomyoma, with a biological behavior between leiomyoma and leiomyosarcoma. A review of the medical literature indicates that gastrointestinal bleeding in the most usual manifestation. The endoscopy biopsy, many times, is unable to confirm the malignant or benign of the tumor. It is emphasized the importance of identifying the potentially malignant tendency of the tumor, indicated, mainly, by histology consist in total gastric resection. Radiology, Ultrasound and Endoscopy are the most frequently used methods to arrive at diagnosis. In our case a patient with a presumed diagnosis of gastric cancer with a severe upper gastrointestinal hemorrhage was operated on as an emergency. A radical extended total gastrectomy was performed. Intraoperative findings included multiple pancreatic, hepatic, splenic, hilium, greater and lesser omental metastases. The patient was released in good condition but died 3 months later.
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PMID:[Gastric epithelioid leiomyosarcoma (malignant leiomyoblastoma). Report of a case and review of the world literature]. 184 56

Clinical symptomatology, pathology and surgical management of five patients with gastric leiomyoblastoma are reported. Leiomyoblastomas of the gastrointestinal tract are defined as a group of tumors, which originate from the smooth muscle, and which have to be classified in between benign leiomyomas and malignant leiomyosarcomas. These tumors metastasize in about 10% of cases. Patients come to the hospital in most cases because of unspecific upper abdominal symptoms. During surgery one usually finds solitary, well defined, cystic tumors of a size of 0.5 to 30 cm expanding intramurally versus neighbouring structures; ulcerations of the gastric mucosa are rare. The diagnosis is established by microscopic examination during surgery. Treatment is extensive excision of the tumor.
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PMID:[Leiomyoblastoma of the stomach (author's transl)]. 710 16