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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The retroperitoneal tumors are seldom met in their several histological expressions. Authors totally considered 27 patients with retroperitoneal tumors and they were observed from 1975 to 1996: 21 of them were primitively cured in this Institute whereas 6 were affected with relapse or metastasis after a surgical approach which had been performed by other structures. Their operability resulted of 100% with an 87% resectability rate. The surgical mortality resulted nil while the morbidity rate was of 44%. The global survival resulted of 60% to 5 years while the disease-free interval was of 35%. The outliving to 5 years resulted of 65% with a 60% disease-free interval only in the patients who were treated in first instance. The surgical therapy represents the only treatment which can modify the clinical history of such neoplasms. Exeresis should be aggressive enough in order to obtain a total extirpation of the mass and grant a right margin of safety of sound tissue. Such radical proceeding should also be pursued in the treatment of relapses and metastases. The therapeutical efficacy is always linked to the precocity the diagnosis. A strict follow-up of the patients who underwent a surgical operation for retroperitoneal neoplasm is therefore necessary. A minority of the instances was only subjected to a complementary radio and/or chemotherapic treatment. Such protections did not significantly modify the outliving.
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PMID:[Retroperitoneal tumors]. 1069 94

The Authors report a rare case of undifferentiated duodenal malignant stromal tumour in a 69-years-old man radically managed by pancreaticoduodenectomy and resection of a liver metastasis. Several preoperative tests were performed (barium meal, endoscopy, ultrasonography and CT scan) but failed to yield a differential diagnosis between a tumour of the pancreatic head and a retroperitoneal neoplasm. The diagnosis was only histological. The tumour was considered to be high-grade due to its large size, high mitotic index, and the presence of necrosis and liver metastasis. Thorough surveillance revealed several hepatic metastases 29 months after resection, and chemotherapy performed at this stage proved completely ineffective. The patient died 38 months after surgery.
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PMID:[Malignant stromal tumors of the duodenum. Report of a case]. 1120 11

The Authors report a rare case of retroperitoneal leiomyosarcoma in a 80 years woman with respiratory symptoms and right abdominal pain. A large neoplasm occupied the right abdomen, looking asymmetric. Upper abdominal CT showed a retroperitoneal neoplasm close to right kidney, liver, aponeurosis of right oblique muscles, producing a left-side dislocation of the intraabdominal organs. A surgical "en bloc" resection of the neoplasm was performed; neoplasm was plurilobed and capsulated. The histologic examination confirmed the diagnosis of leiomyosarcoma. The best treatment of these neoplasms is surgery, that in the last years has drawn advantage from more sensible and specific diagnostic procedures, which show a more radical surgical option. Though metastases are occasional, local recurrences can be taken into consideration and, after a careful tumoral re-staging, they can be resected once more. Therefore, a careful follow-up is necessary on the basis of neoplastic grading, extension and involvement of the closer structures.
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PMID:[Retroperitoneal leiomyosarcoma: a case report]. 1538 79