Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A retrospective comparison was made of the capability of magnetic resonance (MR) imaging and CT to display and characterize pathologic abdominal fluid collections. Fluid collections in 41 patients were analyzed: ascites (seven patients), hematoma (five), pancreatic pseudocyst (four), biloma (two), abscess (four), simple renal cyst (nine), hemorrhagic renal cyst (two), hydronephrosis (four), hemonephrosis (two), and cystic metastases (two). Most fluid collections were equally demonstrated by the two modalities. Walls around fluid collections were better demonstrated CT. Six fluid collections appeared heterogeneous on MR but were homogeneous or nearly so on CT.
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PMID:MR imaging of pathologic abdominal fluid collections. 374 43

Grey scale abdominal ultrasound was used in a total of 146 children for primary diagnostic evaluation of abdominal masses and for follow-up of patients with malignant diseases. Of 93 patients examined for a suspected abdominal mass, 6 showed to have an intraabdominal tumour. In each case the site of tumour origin could be ascertained by ultrasound. The remaining 87 patients showed no pathological findings and have been tumour-free at routine follow-up studies. Sonography proved to be also useful in the follow-up of patients with malignant diseases. Local recurrence or metastases could be ruled out on the basis of sonographic findings alone in 32 out of 35 surgically treated patients, in 3 children with non-resectable tumours, changes in tumour size during radio- and chemotherapy could be studied. Diagnostic ultrasound was also of great importance in the assessment of complications after surgery, radio- and chemotherapy. So the early detection of hydronephrosis in 2 patients with treated nephroblastoma prevented a damage of the remaining kidney. Due to the high accuracy of sonography, invasive diagnostic methods could be restricted to a small number of patients in whom ultrasound failed to provide adequate information.
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PMID:[Ultrasound diagnosis of malignant diseases in pediatrics]. 388 61

Forty-four patients with symptomatic hepatic metastases from a colon primary had CT prior to radiation therapy treatment planning. A control group of 44 patients with no evidence of liver metastases was analyzed for comparison. The objectives of planning were to deliver as homogeneous a dose to the whole liver as possible and no treat one kidney or more than one-half of both kidneys. Conventional anteroposterior/posteroanterior portals were found to be inadequate for the treatment of 60% of patients with metastases and 10% of patients with no liver involvement. Among the metastatic group, 50% required oblique planning, 40% anteroposterior/posteroanterior and 9% posteroanterior and left lateral portals to meet the treatment planning objectives. Among the control group of patients with no liver metastases, only 9% required oblique portals and 8% could not be treated because of left hydronephrosis or a solitary right kidney. It is concluded that all patients receiving radiation therapy to the liver for symptoms or prophylaxis require CT for optimum radiation therapy treatment planning.
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PMID:Computed tomography in radiation therapy treatment planning of hepatic metastases. 392 35

Prostate carcinoma occasionally can present with rectal obstructive symptoms and an annular constricting lesion of the rectum. Discriminating between primary rectal carcinoma and prostate carcinoma locally invasive to the rectum is of obvious importance because of the different treatments and prognoses. History and physical examination play only a marginal role in differentiating between these two lesions. The diagnosis of prostatic malignancy in patients in this circumstance can be supported by an elevated serum acid phosphatase as well as a bone scan that demonstrates a pelvic/vertebral distribution of bony metastases. The rectal mucosa is usually spared, and a barium enema often will demonstrate tapered margins as opposed to a tumor edge in primary rectal malignancy. Excretory urography often demonstrates hydronephrosis. Rectal biopsy with immunohistochemical staining for prostate specific antigen can direct the origin of a poorly differentiated adenocarcinoma to the prostate. Treatment involves hormonal manipulation with estrogen therapy or orchiectomy. Radiation therapy to the obstructed rectum has provided satisfactory palliation when hormonal manipulation fails.
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PMID:Invasive carcinoma of prostate presenting as rectal carcinoma. 394 39

In a retrospective 4 year study, 19 patients with unresectable recurrent pelvic tumor secondary to colorectal adenocarcinoma underwent urinary diversion. An ileal conduit was performed for palliative purposes at the time of exploration. None of the 19 patients had evidence of distant metastases. Survival after the ileal conduit ranged from 2 to 26 months (median 13 months). This survival rate did not vary significantly according to sex or whether hydronephrosis resolved after urinary diversion. Postoperative complications developed in three patients. Two of these complications were ureterointestinal anastomotic leaks and the third was development of an enterocutaneous fistula. The quality of life was rated as good by 75 percent of the patients and fair by 18 percent, with all patients relieved of painful obstructive uropathy. Eighteen of 19 patients were able to resume useful and productive lives.
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PMID:Ileal conduits for recurrent unresectable colorectal adenocarcinoma. 402 5

The sonographic findings in the abdomen in 42 patients with intra-abdominal metastases from malignant melanoma are described. Multiple metastatic sites were seen in 10 of the 42, with the liver being the organ most often involved. Liver metastases were predominantly of low echo amplitude, and fluid was visible within 30 per cent of all metastases, probably being an indicator of the frequency of hemorrhage into these lesions. Bulky disease, especially in the retroperitoneum, was unusual in the patients examined, which probably accounts for the absence of hydronephrosis as a complication.
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PMID:The sonographic appearance of metastatic malignant melanoma. 615 30

A case of malignant fibrous histiocytoma (MFH) occurring in th retroperitoneum with giant pyonephrosis is reported. The patient was a 45-year-old male and his chief complaint was an abdominal mass. The abdominal fullness progressed so rapidly that he was admitted to our hospital. After examination, this case was diagnosed as a malignant tumor with left hydronephrosis, and an operation was performed on August 5, 1982. At operation, the left kidney contained about 11,000 ml of a pus-like fluid and in the retroperitoneum was found a hen-egg-sized solid tumor which was invading into the left kidney and the feeding vessels of the descending colon. So the tumor, left kidney and a part of the descending colon were resected en bloc. Pathological diagnosis was malignant fibrous histiocytoma. Chemotherapy (PPM regimen) and immunotherapy (OK-432) were administered after the operation, but multiple metastases appeared in the liver and bilateral lungs within 3 months. Then, the CY-VA-DIC regimen was followed. But, local recurrence was found in about 5 months, and the patient died on the 174 th day after the operation. Local recurrence and metastases in the liver, bilateral lungs, pleura and bones were confirmed at autopsy. Besides our case, a review of case reports of retroperitoneal MFH in Japan and comments are presented.
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PMID:[A case of malignant fibrous histiocytoma occurring in the retroperitoneum with giant pyonephrosis]. 632 41

The metastatic sites of infiltrating duct (IDC) and infiltrating lobular carcinoma (ILC) have been compared using both clinical and autopsy data. The following statistically significant differences were found: Lung parenchymal metastases were more common in IDC. Bone trephine biopsies were more likely to be positive in ILC. Carcinomatous meningitis was associated almost exclusively with ILC. Peritoneal/retroperitoneal metastases of distinctive pattern occurred in ILC. There was often associated linitis plastica-like involvement of the stomach wall and diffuse infiltration of the uterus. Hydronephrosis was a common secondary phenomenon.
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PMID:A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast. 633 84

The urographic results obtained in 14 patients with tumors of the renal pelvis are compared with those of computer tomography (CT), and the diagnostic possibilities emerging from CT are described. CT is superior to urography and angiography not only in the discovery of renal pelvic tumors but also in their further differentiation. In addition, CT gives information in case if bilateral processes and lymph node metastases. Nonetheless, intravenous pyelography continues to hold the first place in the diagnosis of pathological processes of the renal pelvis. This holds both for tumor detection and suspicion and for indirect signs, namely the "mute" kidney or hydronephrosis. Angiography is less information with renal pelvic tumors, and with ultrasonic diagnostics there is no sufficient experience up to now.
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PMID:[Tumors of the renal pelvis--diagnostic possibilities using CT]. 647 27

Abdominal CT examination is the method of choice when examining ovarial tumours. Abdominal CT is redundant in the early stages of carcinoma of the collum and if the carcinoma has penetrated into the vagina. In advanced stages of carcinoma of the collum, CT enables accurate staging. CT is at least equal in relevance to gynaecological examination in respect of assessment of parametraneous infiltration. Distant metastases, as well as complications of the efferent urinary tract can be visualized. In view of this, the following procedure appears meaningful in advanced carcinoma of the collum: First of all, gynaecological examination is performed without anaesthesia to confirm the findings in the regions of the portio and vagina; as far as possible, the existence of the central parametraneous infiltrations is confirmed. For the purpose of further staging of the parametraneous infiltration, as well as of the paraaortal lymphomas and possible metastases, as well as for the purpose of excluding hydronephrosis, computed tomography is performed. This avoids burdening the patient with an examination under anaesthesia, and it also avoids invasive examination methods, such as urography and lymphography.
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PMID:[Value of computer tomography in gynecological tumors]. 665 23


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