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Query: UMLS:C0027627 (metastases)
 103,950 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Only 12 cases of nasal hemangiopericytoma have been reported in the literature. Ten additional cases are presented herein. Surgical excision is the recommended treatment; cryosurgery was used in one of our patients. Four of the tem patients had recurrences, one of which proved to be malignant (with distant metastases to the lung) and was ultimately fatal.
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PMID:Hemangiopericytoma of the nasal cavity. 11 30

A recurred and metastasized hemangiopericytoma of menigeal origin caused a terminal hypoglycemia syndrome in a 40 year old man. The disease had been observed over a period of 10 years. The total weight of the tumour metastases was 1800 g. Electron microscopical examination of the tumour cells revealed, in particular, a markedly developed ergastoplasm, prominent Golgi complexes surrounded by many microvesicles, round to ovoid electron dense bodies and fine fibrillar structures. Furthermore, large deposits of basement membrane-resembling material were found in the pericapillary and intercellular spaces. On the basis of the structural characteristics which indicate distinct synthesizing capacity of the cells, an excessive glucose consumption by the tumour is suggested to be an important factor in the pathogenesis of tumour hypoglycemia. The question whether the ultrastructure of the tumour also exhibits secretory processes, which may be related to the release of a presumed inhibitor of hepatic gluconeogenesis and/or glycogenolysis, remains open. Typical granules as in polypeptide hormon secreting cells were not observed. The possibility that the demonstrated electron dense membrane limited bodies represent atypical secretory granules is discussed.
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PMID:Ultrastructure of hemangiopericytoma associated with paraneoplastic hypoglycemia. 13 25

Hemangiopericytomas of the meninges are rare tumors. Three tumors of this type with a course over more than 10 years each are reported. All three tumors were primary diagnosed as meningiomas (one: vascular, two angioblastic). The diagnosis was changed to hemangiopericytoma only then when recurrences and extracranial metastases had occurred. Morphologically, "angioblastic meningioma" and "hemangiopericytoma of the meninges" show striking common features. The principal pattern bases on the blastomatous increase of capillary blood vessels lined by a normal endothelium, extracapillary proliferation of pericyte-like mesenchymal cells and an intercellular network of reticulin fibres. Light- and electron microsopic findings do not demonstrate the characteristics of a meningioma. Furthermore, clinical data and growth pattern of "angioblastic meningioma" and "hemangiopericytoma of the meninges" are well comparable. Therefore, it seems to be justified to interpret these tumors as a tumor entity with identical histogenesis. It is well known that hemangiopericytomas frequently recur and metastasise. On the other hand, meningiomas are usually benign. For those reasons we suggest that these tumors should be uniformly classified as "hemangiopericytoma of the meninges" in order to stress the significance of these particular tumors of the meninges regarding their treatment and behaviour.
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PMID:[Morphology and clinical significance of the meningeal hemangiopericytoma (author's transl)]. 13 28

The experience in treating three patients with hemangiopericytoma is reviewed. One patient was given irradiation alone, and the others were both treated with surgery and irradiation. Our experience reinforces reports of the usefulness of irradiation in treating this neoplasm and its metastases.
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PMID:Hemangiopericytoma: report of three cases regarding role of radiation therapy. 17 62

The clinical and pathological findings of six cases of leiomyosarcoma arising from blood vessels of different caliber are described. The term vascular leiomyosarcoma, having both a topographic and morphologic significance, is proposed for these tumors. The histologic pattern is characterized by a proliferation of atypical smooth muscle cells with a large number of intermingled blood vessels. Mitoses were counted per 10 high power field (hpf) and tumors were divided in three groups I, 10 to 20 mitoses, group II, 20 to 35 mitoses, and group III, more than 35 mitoses per 10 hpf. The mitotic index seems to be the most important pathological feature on which a prognostic evaluation for vascular leiomyosarcoma can be based. Tumors in group I had neither local recurrences nor metastases; the one tumor in group II had one local recurrence, but the patient is free of disease 6 years after surgical treatment; the three tumors in group III developed distant metastases and constitutional symptoms. Vascular leiomyoma, bizarre leiomyoma, and hemangiopericytoma are included in the differential diagnosis of vascular leimyosarcoma. The possibility that vascular leiomyosarcoma arising from small vessels represents the malignant counterpart of vascular leiomyoma is proposed.
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PMID:Vascular leiomyosarcoma: the malignant counterpart of vascular leiomyoma. 49 39

A report of 2 cases of solitary fibromatosis in a 10-day-old boy and a girl 3 years and 10 months old is presented. Both lesions were deep-seated and showed a nodular and infiltrating growth, predominantly buil-up by immature fibroblast-like cells and including hemangiopericytoma-like areas. One of the lesions also showed leiomyoma-like areas. An ultrastructural study however, revealed no intra-cytoplasmatic myofilaments. At follow-up examinations after 21 years and 1 year, respectively, there were no signs of recurrences or metastases. These 2 cases are considered to represent a solitary form of congenital generalized fibromatosis. The differential diagnosis from infantile hemangiopericytoma and fibrous lesions seen in infancy and early childhood, such as infantile fibrosarcoma, diffuse infantile fibromatosis, extra-abdominal desmoid, fibrous hamartoma of infancy and juvenile aponeurotic fibroma, is discussed.
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PMID:Congenital solitary fibromatosis of soft tissues, a variant of congenital generalized fibromatosis. 2 cases reports. 92 Jan 81

Analysis of 78 observations (including 6 of the author's own) of primary malignant vascular tumours of the lung, showed that these tumours had no characteristic clinicoroentgenological features; in this connection the question of their preoperative cytological diagnosis is of importance. The retrospective collations of cytological and histological data in 8 patients made it possible to establish criteria of cytological diagnosis of similar tumours. For the first time in the Soviet literature a suggestion was put forward that basing on the data of cytological investigations it is possible in a number of cases to give a detailed verification of tumours of the lung with presumable indication to hemangioendothelioma, angiosarcoma, or hemangiopericytoma. Metastases of malignant vascular tumours of other localizations in the lung are of analogous cytological pattern. correct diagnosis of primary of metastatic tumour can be made only if all the complex of clinico-roentgenological and cytological data are taken into account.
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PMID:[Malignant vascular tumors of the lung (cytologic and histologic parallels)]. 94 55

Primary hemangiopericytoma of the lung is exceedingly rare. The following characteristics were found in a survey of the 34 cases published so far in the world literature and in one case of our own, a 29 year old man with this mesenchymal tumor. It does not show specific clinical signs. In radiographs an isolated round unidentifiable focus is seen. The differential diagnosis has to rely on the histology. About one half of these tumors are discovered by accident. It appears that it occurs at a somewhat younger age in men than in women. Both sexes are equally represented. The treatments of choice are either lobectomy or pneumonectomy. Patients with small tumors without clinical signs appear to have a better prognosis. When recurrence or metastases develop they will be noticed within a few months. Intensive follow-up of patients operated on is essential, since histology cannot provide safe criteria on which one could decide whether the tumor was benign or malignant.
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PMID:[Primary hemangiopericytoma of the lung (author's transl)]. 108 63

Haemangiopericytoma is an uncommon tumour of vascular origin. The authors report a case of one of the rarer sites of this tumour in man: paravesical pelvic haemangiopericytoma. Although modern imaging techniques have provided useful information concerning the hypervascular and clearly demarcated appearance of this tumour which displaces but does not invade adjacent organs, its diagnosis can only be established by histology. Its degree of malignancy and its invasive potential are unclear. The risk of local recurrence and metastases in more than one half of cases justifies wide surgical excision, possibly combined with adjuvant radiotherapy, and long-term follow-up.
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PMID:[A case of hemangiopericytoma of the pelvis]. 130 65

Hemangiopericytoma is a vascular tumor originating from the pericytes which surround the capillaries. The tumor occurs anywhere in the body preferably at head and neck and the extremities. In less than 3% it grows in the stomach. In spite of surgical excision local recurrence or hematogene metastases must be expected. We report a case of primary hemangiopericytoma of the stomach which could only be diagnosed by metachrone liver metastases. This case shows that hemangiopericytomas and their metastases belong to the differential diagnosis of cystic liver lesions. Diagnostic procedure, therapy and prognosis of this rare tumor is discussed by an analysis of the literature.
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PMID:[Metastatic hemangiopericytoma of the stomach. Case report and review of the literature]. 148 53


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