Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027497 (nausea)
 23,468 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We investigated the efficacy of acupressure and acustimulation in alleviating symptoms of Simulation Adaptation Syndrome (SAS). Twenty-five drivers (mean age = 35.6) reporting a history of driving-related sickness, motion sickness, and/or seasickness were recruited for a within subject, repeated-measures crossover study. Of all participants, 16 reported SAS during a placebo condition. These 16 participants drove the Atari research simulator for 15 minutes on 3 separate days (same time each day), wearing: (a) a placebo device, (b) acupressure beads, and (c) an acu-stimulation device. Every 3 minutes during each drive, participants rated their physical discomfort. Overall, the analysis of variance condition effect was significant (p < 0.05). Participants in the acustimulation condition reported significantly less physical discomfort (p < 0.005) compared with the placebo. There were no significant differences between the acupressure and placebo conditions or the acupressure and acustimulation conditions. These data suggest that acustimulation can help to significantly reduce or prevent SAS-related nausea and physical discomfort.
Mil Med 2011 Dec
PMID:Effectiveness of acupressure and acustimulation in minimizing driving simulation adaptation syndrome. 2233 62

We report the case of a 59-year-old military beneficiary that presented to the emergency department after ingesting approximately 90 g of gabapentin immediate-release capsules during a deliberate self-harm attempt. Her serum gabapentin level was 72.8 mcg/mL approximately 3 hours after ingestion. Her renal function panel, complete blood count, and liver function panel were normal. Her urine drug screen, aspirin, ethanol, and acetaminophen level were negative. Her electrocardiogram was normal, including a normal QTc interval. Her only symptoms were nausea and mild sedation. She was admitted for observation with no sequelae noted. She was transferred to a psychiatric facility at that time for further evaluation and treatment. We report a case of gabapentin overdose that presented to the emergency department. Given the large volume ingestion with minimal morbidity, it appears that gabapentin has a wide therapeutic margin and may be safe in overdose.
Mil Med 2013 Jan
PMID:Gabapentin overdose in a military beneficiary. 2376 59

Chilaiditi's sign is a radiological finding that occurs when the small or large intestine is positioned superior to the liver in the sub-diaphragmatic space. This is typically an asymptomatic radiological sign, but when symptoms occur, e.g., abdominal pain, nausea, emesis, it is termed Chilaiditi's syndrome. Currently, majority of the cases of Chilaiditi's syndrome, described in the literature, requiring operative intervention are due to large bowel obstruction or colonic volvulus. The following is a single case report of a patient presenting to Keesler Medical Center in Biloxi, Mississippi. This report details a 57-yr-old female who has found to have Chilaiditi's syndrome causing a high-grade small-bowel obstruction. She failed non-operative intervention and required exploratory laparotomy, lysis of adhesions, and manual reduction of small bowel from the sub-diaphragmatic space. The rate of failure of non-operative management of Chilaiditi's syndrome has not been established. Our patient had a surgical history of laparotomy and was found to have adhesions superior to her liver. Patients with prior abdominal surgery may require a lower threshold for operative management for Chilaiditi's syndrome due to the possibility of concomitant adhesive disease particularly if the prior procedure involved the upper abdomen.
Mil Med 2018 05 01
PMID:Chilaiditi's Syndrome Causing High-Grade Small-Bowel Obstruction Requiring Exploratory Laparotomy. 2941 92

Diabetic ketoacidosis (DKA) is a severe medical condition involving the uncontrolled hyperglycemia and ketoacidosis that results from impaired insulin utilization. The biochemical response to insulin resistance or deficiency is a ketotic state in which fatty acids are converted to ketone bodies for an alternative energy source. Patients in DKA acutely develop severe symptoms, typically over the course of 24-48 hours. Classic symptoms include nausea, vomiting, lethargy, altered mental status, and abdominal pain. As the time course of ketoacidosis is relatively rapid, it is rare to identify a developing case of DKA prior to symptom onset. In this atypical case, the author presents an asymptomatic 37-year-old active duty male without a history of diabetes, whose DKA detection was inspired by an elevated breathalyzer reading. The Sailor underwent routine breath alcohol analysis per command instruction upon reporting for duty. In the absence of recent alcohol intake, the elevated breathalyzer reading is associated with the Sailor's metabolic ketoacidosis. Acetone, one of three primary ketone bodies generated in DKA is notable as the cause of the hallmark fruity odor breath of DKA patients. In this case, it is converted to isopropanol, an agent that is detectable by breathalyzers.
Mil Med 2019 12 01
PMID:Early Detection of Diabetic Ketoacidosis by Breathalyzer in a Sailor Reporting for Duty. 3114 Nov 43

Cannabinoid hyperemesis syndrome presents with abdominal pain, nausea, and intractable vomiting caused by phytogenic and synthetic cannabinoid use. Complications associated with this disorder range from severe dehydration to acute kidney injury and rhabdomyolysis. This syndrome mimics many acute surgical and emergency medical conditions and can present several diagnostic and treatment challenges. While this syndrome is increasingly recognized as a common clinical entity in civilian emergency departments, there is little data concerning experience at military hospitals. We present a case of cannabinoid hyperemesis syndrome that was diagnosed and treated in a combat-zone US military emergency department in Southwest Asia.
Mil Med 2020 09 18
PMID:Cannabinoid Hyperemesis Syndrome: An Unexpected Problem in an Unusual Setting-A Case Report. 3247 23


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