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Query: UMLS:C0027497 (nausea)
 23,468 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The diuretic response of patients with congestive heart failure to establish doses of diapamide (750 mg) and furosemide (80 mg) was compared in an open, crossover study. Peak urine output occurred in the first 6 hours after administration of furosemide but somewhat later (12 to 18 hours) with diapamide. Both agents produced active diuresis and natriuresis in most patients. Comparisons of drug effect during the first days of each treatment period and analysis of the entire first treatment period indicated that urine output with furosemide was significantly greater than with diapamide. Urinary sodium excretion on the first day of treatment was not significantly greater with furosemide than with diapamide, nor were the differences significant on subsequent days. The observed differences between drugs on urinary potassium and chloride excretion were not statistically significant. The most frequently occurring adverse reaction was mild to moderate nausea, which was reported by five patients receiving diapamide and two patients receiving furosemide. Diarrhea and vomiting were also more frequent with diapamide. Diapamide would appear to serve a role between the milder thiazide diuretics and the more effective furosemide.
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PMID:Evaluation of a new diuretic, diapamide, in congestive heart failure. 37 Jan 57

When taken regularly, oral contraceptives (OCs) are 99% effective in preventing pregnancy. This information sheet identifies the difference between the 28-day or 21-day packet of pills and reviews how OCs work and how they affect the menstrual cycle, what do do if one misses a pill, side effects, and ensuring maximum protection. The only difference between the 28-day and the 21-day packet of pills is the 7 inactive pills in the 28-day packet. With the 28-day pack, one starts the packet on the 1st day of menstrual bleeding, taking the pill from the shaded section marked with the appropriate day. One continues to take the pills every day, in the direction indicated by the arrows. The next period will occur when one returns to the inactive pill section. With the 21-day packet, the 1st packet is started on the 5th day of menstrual bleeding, whether or not the bleeding has stopped. One's menstrual period will occur 2-4 days after finishing the last packet. The pill prevents pregnancy by changing the hormone balance in the body to stop ovulation. Menstrual periods tend to become shorter and lighter. If a pill is missed the forgotten pill must be taken as soon as possible, even if it means taking 2 pills in 1 day. The most common side effects include nausea, breast tenderness, and breakthrough spotting. More serious side effects include migraine headaches and high blood pressure. Diarrhea and vomiting may reduce the absorption of the pill; to ensure maximum protection in those cases, one should keep taking the course of the pill but use additional contraception until the end of the packet.
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PMID:The pill. 380 Jul 76

Heat stroke (HS) is a serious and potentially life-threatening condition defined as a core body temperature >40.6 degrees C. Two forms of HS are recognized, classic heat stroke, usually occurring in very young or elderly persons, and exertional heat stroke, more common in physically active individuals. An elevated body temperature and neurologic dysfunction are necessary but not sufficient to diagnose HS. Associated clinical manifestations such as extreme fatigue; hot dry skin or heavy perspiration; nausea; vomiting; diarrhea; disorientation to person, place, or time; dizziness; uncoordinated movements; and reddened face are frequently observed. Potential complications related to severe HS are acute renal failure, disseminated intravascular coagulation, rhabdomyolysis, acute respiratory distress syndrome, acid-base disorders, and electrolyte disturbances. Long-term neurologic sequelae (varying degrees of irreversible brain injury) occur in approximately 20% of patients. The prognosis is optimal when HS is diagnosed early and management with cooling measures and fluid resuscitation and electrolyte replacement begins promptly. The prognosis is poorest when treatment is delayed >2 hours.
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PMID:Heat stroke: a comprehensive review. 1546 Oct 44