Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027497 (nausea)
 23,468 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Existing international literature concerning complications stemming from the use of the IUD is reviewed. They are either immediate or delayed. Immediate complications are (partial) perforation of the uterus, vagal reaction, bleeding, and pain. Perforation should be followed up by echography or radiography. Hysteroscopy or celioscopy allows for recovery of the device. Vagal reaction, manifested by bradycardia, hypotension, pallor, sudation, nausea, even cardiac arrest, occurs with stenosis of the cervical canal predominantly in emotive and/or nulliparous women. Bleeding occurs from trauma caused by the IUD to the mucus of the endocervix and/or endometrium. Pain is an almost constant symptom that appears at the moment of insertion, more frequently in young nulliparae than multiparae, and disappears spontaneously after 5-10 minutes. Delayed complications are menometrorrhagia, often accompanied by dysmenorrhea, lost IUD, total or partial expulsion, ectopic pregnancy and pelvic infections (PID). Menometrorrhagia seems imputable more to an increase of fibrinolytic activity of the endometrium in contact with the IUD than to plasmatic alterations of the progesterone, estradiol or gonadotropin. Lost IUD generally is due to rotation caused by uterine contractions, or the thread being cut off too close to the mouth of the external uterus. Fracture of the IUD as well as migration toward the fallopian tubes are very rare. The FDA reports, in 1979, that ectopic pregnancy is verified more frequently in women carrying the device medicated with progesterone. PID are 10 times more frequent in young women having used the IUD for at least 2 years. A significant increase in PID is also reported for women who use the device for more than 5 years.
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PMID:[Side effects and complications of intrauterine devices with special reference to pelvic infection]. 380 30

203 women 19-40 years of age were administered the gestagen preparations Volidan, Cyclofarlutal, Ovulen, Ciba AC-101, and Stediril as a contraceptive. 49 other women were administered these preparations as therapeutic and/or diagnostic measures in different gynecological complications. Side effects such as spotting, acylic bleeding, nausea, headaches and breast swelling were more frequent with the high-dose preparations such as Volidan and Cyclofarlutal. Intolerance to the preparation and subsequent discontinuation occurred only in a small percentage of the users. All of the preparations achieved 100% effectiveness as contraceptives. It is noted that these preparations were used with some success in treating dysmenorrhea, menometrorrhagia because of hyperplasia of the endometrium, and in severe climacteric syndromes. It has also been used as a pregnancy test. Constant medical control of the administration of these preparations is necessary both when they are used as contraceptives and as therapeutic measures, particularly in the case of young women.
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PMID:[Clinical aspects of the administration of gestagen preparations (Volidan, Cyclofarlutal, Ovulen, Ciba AC-101 and Steridil)]. 545 44

One hundred women without cervical lesions underwent hysterectomies for uterine myomas or menometrorrhagia unresponsive to medical therapy after being randomized into two groups (50 for LH and 50 for SCLH), uterine fundal measurements were 6 to 10 cm in greatest diameter. We evaluated operating time, blood loss, the postoperative incidence of nausea and emesis, the need for analgesics, and resumption of oral tolerance and ambulation. Using the Student t Test, a clinically statistically significant improvement was noted in the quality of the postoperative period in women undergoing SCLH as compared with those undergoing LH. Patients undergoing SCLH reported feeling 'less castrate' than those undergoing traditional total LH.
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PMID:Supra-Cervical Laparoscopic Hysterectomy (SCLH) vs. Total Laparoscopic Hysterectomy (LH): A Comparative Post-Operative Study 907 44