Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027497 (nausea)
 23,468 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of agenesis of the internal carotid artery combined with arachnoid cyst is reported. This 11-year-old boy had occasionally complained headache and nausea since he was of 9 years old. He was admitted to our hospital because of an epileptic seizure. Physical and neurological examinations on admission were normal. A CT scan showed a cystic mass in retrocerebellar region. MRI suggested absence of flow void area indicating internal carotid artery in the cavernous sinus on left side. Left common carotid angiogram showed absence of the internal carotid artery. Bilateral A2 segments were supplied by right A1 with tortuous anterior communicating artery. Left middle cerebral artery and left ophthalmic artery were supplied via dilated left posterior communicating artery on left vertebral angiogram. Thin slice, axial target image of the CT revealed absence of the left bony carotid canal. MRI by 3D TOF method confirmed no blood flow in this area. MR angiography provided sufficient information about cervical vessels non-invasively. 123I-IMP SPECT image ascertained no hypoperfusion area in left cerebral hemisphere. Convulsion was controlled with sodium valproate. Association of agenesis of the internal carotid artery and arachnoid cyst could be a coincidence.
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PMID:[Agenesis of the internal carotid artery--report of a case combined with arachnoid cyst in a child]. 163 34

This report concerns a 51-year-old right-handed man with Japanese encephalitis, showing left hemiplegia and left hemispatial neglect. On admission, he had a slight fever, mild consciousness disturbance, left hemiplegia, and left hemispatial neglect but no neck stiffness, headache nor nausea. He was treated on the basis of cerebral infarction, but his fever and consciousness disturbance worsened. We found pleocytosis (145/mm3) in the cerebrospinal fluid (CSF) and right thalamic edema on a brain CT scan obtained 4 days later. He was finally diagnosed as having Japanese encephalitis on the basis of an increase in anti-viral antibodies observed in paired CSF and serum samples. In the exacerbation phase, 123I-IMP single photon emission CT (SPECT) demonstrated a marked decrease in cerebral perfusion in the right hemisphere, while a brain MRI revealed irregular lesions localized the right thalamus (mainly posterior and medial parts), showing low intensity on T1-weighted and high intensity on T2-weighted images. In the recovery phase, asymmetrical perfusion was no longer observed on SPECT and the symptoms including the left hemispatial neglect had improved. These findings suggest that the left hemispatial neglect in this patient might been caused by the right thalamic lesion resulting in damage to the activating system of the right hemisphere. This case thus shows that acute onset of hemispatial neglect could be caused by cerebral encephalitis.
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PMID:[Japanese encephalitis presenting with left hemiplegia and thalamic neglect--a case report]. 1125 92

Cerebral hemodynamic and metabolic changes in intracranial hypertension associated with sinus thrombosis have not been well documented. We report pre- and post-treatment changes in cerebral hemodynamic and metabolic parameters in a 50-year-old male who presented intracranial hypertension due to sinus thrombosis, using single-photon emission computed tomography (SPECT) and positron emission tomography (PET). He complained of headache, nausea and double vision and was admitted to our hospital. Neurological examinations on admission revealed papilledema on both sides. Cerebrospinal fluid pressure was 28 mmHg. Cerebral angiography showed occlusion of the superior sagittal sinus and retrograde filling of the ascending cortical veins in the bilateral frontal lobes. 123I-IMP SPECT and 15O-gas PET showed a reduction of cerebral blood flow and oxygen metabolism and an extreme elevation of cerebral blood volume in the bilateral cerebral hemispheres. His complaints resolved after lumbo-peritoneal shunt. Postoperative SPECT/PET studies demonstrated improvement of hemodynamic and metabolic parameters. Intracranial hypertension and associated venous congestion were most likely related to hemodynamic and metabolic abnormalities.
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PMID:[Improvement of cerebral hemodynamic and metabolic parameters in a patient who presented intracranial hypertension due to superior sinus thrombosis after lumbo-peritoneal shunt: case report]. 1577 19

Dural arteriovenous fistulae(dAVF) in the anterior cranial fossa comprise about 6% of all dAVFs, and is usually detected after intracranial hemorrhage. However, non-hemorrhagic symptoms are uncommon. We encountered two patients with hemorrhagic and non-hemorrhagic dAVF in the anterior cranial fossa. Both cases were successfully treated using craniotomy and histopathological examination was performed. A 71-year-old male experienced sudden onset of nausea and headache, followed by progression of left hemiparesis and disturbance of consciousness due to intracerebral and subdural hematoma in 2005. Intracerebral venous aneurysm adjacent to the intracerebral hematoma originated from the draining cortical red vein was identified and successfully treated by operation. Histopathological examination revealed disappearance of the internal elastic lamina and scant muscle tissue in the venous aneurysmal wall originating from draining cortical vein. A 69-year-old male suffered sudden onset of mild headache, followed by progression of bruits in 2005. MRI suggested dAVF in the left anterior cranial fossa. 123I-IMP SPECT revealed an area of low perfusion in the left frontotemporal region. Histopathological examination after surgical treatment revealed thickening of the intima and an indistinct lamina elastica interna, indicating progressive degenerative changes of the arterialized vein likely to result in hemorrhage. Surgical obliteration of fistulae is reasonable even in the dAVF of the anterior cranial fossa with ischemic onset.
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PMID:[Two surgically treated cases with dural arteriovenous malformation in the anterior cranial fossa]. 1635 34

An 83-year-old man with 3 years symptomatic hearing loss suddenly experienced musical hallucinosis. He heard children's songs, folk songs, military songs, and the Japanese national anthem for seven months every day. He sometime had paroxysmal nausea, dull headaches and depressive mood. On examination he had no psychosis or neurological symptoms except sensorineural hearing loss in both ears. MRI brain imaging and electroencephalography showed no significant abnormalities, however <sup>123</sup>I-IMP brain SPECT showed decreased activity in the right temporal lobe and increased activity in the left temporal and parietal lobes. Late phase <sup>123</sup>I-iomazenil brain SPECT showed decreased accumulation in the right temporal lobe compared to the early phase. This indicates right temporal lobe epilepsy. He was diagnosed with epilepsy because of paroxysmal nausea and headache and the laterality of <sup>123</sup>I-IMP brain SPECT and <sup>123</sup>I-iomazenil brain SPECT. The musical hallucinosis was much reduced by carbamazepine 200mg per day. Nine months after beginning carbamazepine we detected decreased activity in the right temporal lobe and increased activity in left temporal and parietal lobes was improved. We do not believe he had epileptogenic musical hallucinosis because his musical hallusinosis was neither paroxysmal nor lateral. We diagnosed auditory Charles Bonnet syndrome with onset 3 years after sensorineural hearing loss due to reversible epileptic like discharge in temporal and parietal lobes. There is no established treatment for musical hallucinosis, but anti-epileptic drugs may be of some help.
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PMID:[Successful treatment with anti-epileptic-drug of an 83-year-old man with musical hallucinosis]. 2480 75