Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027497 (
nausea
)
23,468
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Ever since a gradual but significant reduction in the estrogenic and progestogenic components of oral contraceptives (OCs) was made, there has been a corresponding decrease in adverse effects associated with the pill. The beneficial effects include prevention of pregnancy, reduction in pelvic inflammatory disease, protection against ovarian/endometrial cancer and benign breast tumors and ovarian cysts, reduction in the occurrence of rheumatoid arthritis among OC users, and regulation of the menstrual cycle. The adverse effects include diseases of the circulatory system (myocardial infarction, venous thromboembolism,
subarachnoid hemorrhage
, hypertension), possible carcinogenicity (breast, cervix, melanoma), pituitary adenomas, liver disorders, glucose metabolix effects (diabetes), vitamin status alteration, delay in return of menstruation and fertility, and a number of minor side effects (
nausea
, vomiting). Contraindications to OC use include history of malignancy of the breast or genital tract, venous thromboembolism, cerebrovascular accident, undiagnosed abnormal vaginal bleeding, focal migraine, or familial hyperlipidemia. The following situations require medical assessment before OCs are prescribed, and medical supervision if OCs are prescribed: age 40+, smoking and age over 35, mild hypertension or a history of hypertensive disease of pregnancy (toxemia), epilepsy, diabetes mellitus, history of bouts of depression, history of oligomenorrhea or amenorrhea in nulliparous women, and gallbladder disease. Problems could occur with OC use in the following situations: 1) lactation (ideally, OCs should be withheld until the child is weaned but if not possible, OCs should not be given until lactation is established); 2) drug interaction (other contraceptive form should be used when the patient is taking antibiotics or anticonvulsants); 3) tropical diseases (studies are still underway); 4) adolescence (very young girls should use other contraceptive method until regular menstruation is established); 5) postcoital contraception (limited use of steroids in emergency situation); and 6) hormonal pregnancy tests (use of oral steroids for pregnancy testing is not recommended). The 3 main types of OCs currently used are the combined estrogen and progestagen, the progestagen-only OC, and the triphasic OC. The lowest effective dose of a compound should be used, and healthy women may continue to use OCs for many years.
...
PMID:Statement on steroidal oral contraceptives. 1226 73
A 31-year-old woman presented with bilateral ophthalmic segment "kissing" aneurysms causing
subarachnoid hemorrhage
manifesting as sudden severe headache and
nausea
3 days before admission. Cerebral angiography demonstrated bilateral internal carotid-superior hypophyseal artery aneurysms, both projecting medially from the medial surface of the internal carotid arteries and appearing to touch each other. Both aneurysms had to be clipped in the same operation, because of uncertainty over which aneurysm had bled. She underwent bilateral frontotemporal craniotomy on the day after admission. Intraoperatively, the two aneurysms were in contact with each other in the suprasellar cistern. Each aneurysm was clipped through the ipsilateral approach without any incident. The patient returned home a month after the operation and has since resumed her previous work. Identification of this rare entity of bilateral ophthalmic segment "kissing" aneurysms is important for surgical planning. Closely situated, bilateral ophthalmic segment aneurysms require a modified surgical strategy for proximal arterial control and the approach to each aneurysm.
...
PMID:Bilateral ophthalmic segment "kissing" aneurysms presenting with subarachnoid hemorrhage--case report. 1241 65
We are reporting two cases of vertebral artery occlusion resulting from cervical spine trauma. A 41-year-old man experienced vertigo and
nausea
6 hrs after chiropractic manipulation. On admission, he was alert and demonstrated nystagmus, hypalgia of left leg, and right Horner sign. A MR image revealed infarction in the right cerebellar hemisphere. A MR angiogram did not show the proximal part of the right vertebral artery. A right vertebral angiogram revealed right vertebral artery occlusion at the level of C 1. He underwent anticoagulation and wore a cervical collar. He was discharged with hypalgia of left leg. A 53-year-old man was admitted to our hospital after an automobile accident. A CT scan revealed a
subarachnoid hemorrhage
and an intraventricular hemorrhage. A cervical CT scan revealed fractures of the C 5 facet joint and C 6 vertebral body. A MR angiogram did not show the proximal part of the left vertebral artery. A subsequent left vertebral angiogram revealed left vertebral artery occlusion at the level of C 6. He underwent anticoagulation and wore a cervical collar. In addition, he underwent coil embolization of the left vertebral artery. He was discharged with no neurological deficits. It is said that traumatic vertebral artery injuries cause cerebral infarction with time lags. The therapeutic point is to prevent propagation of the thrombus and distal embolism; therefore wearing a collar, anticoagulation, and endovascular interventional therapy is recommended.
...
PMID:[Vertebral artery occlusion following neck trauma: report of two cases]. 1268 94
A 78-year-old female suffered sudden onset of
nausea
and headache. Computed tomography demonstrated diffuse
subarachnoid hemorrhage
. Cerebral angiography demonstrated an aneurysm arising from the right A1 segment of the azygos anterior cerebral artery, and the hypoplastic left A1. A right frontotemporal craniotomy was performed to obliterate the aneurysm by neck clipping. Surgical exploration found the fenestration of the right A1 and showed that the aneurysm had originated from the bifurcation of the fenestrated A1 and a small perforating artery arising from the fenestration. This unusual combination of an aneurysm associated with a fenestration of the right A1 and contralateral A1 hypoplasia may have been caused by local hemodynamic stress.
...
PMID:Aneurysm and fenestration of the azygos anterior cerebral artery--case report. 1279 Feb 84
A thirty-eight year-old lady with a history of bilateral adrenalectomy for Cushing's disease seven years previously, presented with sudden onset of severe headache,
nausea
, vomiting and loss of consciousness. She was somnolent and confused. She had neck stiffness, sixth nerve palsy and mydriasis on the left side. Computerized tomography (CT) and magnetic resonance imaging (MRI) studies revealed a non-homogeneous, grade IV D pituitary mass lesion associated with hemorrhage in the chiasmatic, interhemispheric, cerebellopontine, perimesencephalic cisterns and a hematoma within the frontal lobe. Angiography showed only bilateral elevation of horizontal segments of the anterior cerebral arteries. According to this angiographic evidence, it was presumed that the
subarachnoid hemorrhage
and the intracerebral hematoma were linked to pituitary adenoma apoplexy. ACTH level was 450 pg/ml. The hemorrhagic lesion with suprasellar extension was totally removed by left pterional craniotomy. Histological examination revealed a necrotic, ACTH-secreting pituitary adenoma. Even though apoplexy is a well known complication of pituitary adenomas, to our knowledge
subarachnoid hemorrhage
and intracerebral hematoma as a result of pituitary apoplexy in the context of Nelson's syndrome has not previously been reported.
...
PMID:An unusual presentation of Nelson's syndrome with apoplexy and subarachnoid hemorrhage. 1455 76
A 42-year-old woman presented with very rare cases of ruptured saccular aneurysm of a dolichoectatic internal carotid artery (ICA) associated with agenesis of the contralateral ICA manifesting as sudden onset of severe headache and
nausea
without neurological deficits. Angiography and three-dimensional computed tomography demonstrated intraventricular hemorrhage with slight
subarachnoid hemorrhage
and dolichoectasia of the right ICA with agenesis of the contralateral ICA, as well as a saccular aneurysm of the ectatic right ICA. The aneurysm neck was clipped successfully. The patient remained ambulatory with no neurological deficits at discharge 15 days after the surgery. The saccular aneurysm in our case was formed in the dolichoectatic ICA, presumably due to both abnormal hemodynamics and abnormal arterial wall.
...
PMID:Ruptured saccular aneurysm of a dolichoectatic internal carotid artery in a patient with agenesis of the contralateral internal carotid artery--case report. 1495 32
We report a case of a dissecting vertebral aneurysm with
subarachnoid hemorrhage
(
SAH
) after ischemic onset on the same day. A 48-year-old man had abrupt vertigo and
nausea
. CT & MRI on admission showed no abnormality, but he complained of left hemiparesis after admission. Twelve hours after the ischemic onset he suddenly complained of severe headache and his consciousness deteriorated. The follow-up CT showed diffuse
SAH
. Cerebral angiography showed occlusion of the right vertebral artery at the origin of the posterior inferior cerebellar artery (PICA) and segmental stenosis of the left vertebral artery at the portion distal to the vertebral PICA junction. We treated the patient conservatively. Four days later, he suddenly fell into a coma, but CT showed no bleeding. Because of this we suspected brain stem ischemia due to deterioration of vertebral dissection. The patient died 8 hours after the ischemic reattack. We report difficulty of treatment of a dissecting vertebral aneurysm with simultaneous ischemia and
subarachnoid hemorrhage
.
...
PMID:[Dissecting vertebral aneurysm with subarachnoid hemorrhage after ischemic onset on the same day: a case report]. 1546 62
The frequency of angiographic demonstration of persistent primitive trigeminal artery (PTA) is 0.06 to 0.6%. It is well recognized that approximately 13.8 to 27.8% of patients with PTA also have intracranial aneurysms. However their association with the contralateral occluded internal carotid artery (IC) has not been reported. We reported such an extremely rare case of PTA associated with multiple cerebral aneurysms and a contralateral occluded IC. A 61-year-old female suffered from sudden onset of severe headache with nausea and vomiting. When she was admitted to our hospital, she complained only of headache with
nausea
. Computed tomography demonstrated a diffuse
subarachnoid hemorrhage
. Angiography showed a ruptured anterior communicating artery (Acom). Aneurysm and a left IC-PC large aneurysm with a broad neck. The angiogram also demonstrated a left PTA originating from the cavernous portion of the left internal carotid artery and ending at the midportion of the basilar artery and the contralateral occluded IC in the cervical portion. An operation was performed at day 3 using the left pterional approach, and the two aneurysms were successfuly clipped using the suction-decompression method. The patient was discharged with no neurological deficits.
...
PMID:[Multiple cerebral aneurysms and a contralateral occluded internal carotid artery associated with persistent primitive trigeminal artery]. 1552 91
We report a rare case of multiple aneurysms of the distal posterior inferior cerebellar artery (PICA) associated with recurrent hemorrhage undetectable on preoperative neuroradiological findings. A 68-year-old woman was admitted to our hospital in April, 2003 because of a sudden onset of headache, back neck pain and
nausea
. CT scan at the time of admission showed a hematoma in the 4th & 3rd ventricles, and a mild
subarachnoid hemorrhage
(
SAH
) in the basal, right ambient & quadrigeminal cisterns. She had had a similar history of previous intraventricular hemorrhage and
SAH
in October, 2001. Three-dimensional CT angiograms and left vertebral angiograms performed at that time revealed an irregular vascular lesion at the tonsillomedullary segment (TMS) of the left PICA. However, the final diagnosis was unclear. Left vertebral angiograms at the time of the 2003 admission revealed an irregular vascular lesion in the same region more clearly and the size of aneurysmal dilatations had increased considerably. So, preoperative diagnosis of an irregular vascular lesion at the TMS of the left PICA (distal PICA aneurysm was not ruled out) was based on the above neuroradiological findings. The patient was surgically treated through the suboccipital approach. The TMS of the left PICA had made a difficulty loop formation was observed. Five distinct aneurysma were found on the TMS of the left PICA. To prevent bleeding, the ruptured aneurysm & three unruptured aneurysms were clipped and the residual unruptured one was wrapped with Bemsheets. Postoperative left vertebral angiograms demonstrated neither clipped aneurysms nor occlusive findings at the TMS of the PICA. The patency of the PICA was preserved. The postoperative course was uneventful and the patient was discharged without new neurological deficits. There has been no rebleeding during the one year since surgery. The 23 reported cases of multiple aneurysms of the distal PICA including our case were reviewed and their neuroradiological and clinical features are discussed.
...
PMID:[Multiple aneurysms of the distal posterior inferior cerebellar artery with recurrent hemorrhage undetectable on preoperative neuroradiological findings: case report]. 1557 Aug 81
The great variability of clinical appearance is one of the main features of superior sagittal sinus thrombosis. However, hydrocephalus associated with cerebral sinus thrombosis is rare. We report on a patient presented with thunderclap headache, accompanied by
nausea
, vomiting, and drowsiness. Lumbar puncture ruled out
subarachnoid hemorrhage
, whereas CT revealed marked hydrocephalus. In addition, magnetic resonance venography then confirmed the diagnosis of cerebral sinus thrombosis. It is a rare occurrence but clinically important, since it entails disastrous sequels if unrecognized, and hydrocephalus is treated in the usual fashion with ventricular drainage.
...
PMID:Hydrocephalus due to superior sagittal sinus thrombosis. 1566 88
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>