Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027497 (nausea)
 23,468 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chronic diarrhea is defined as diarrhea that lasts longer than four weeks. Etiology of chronic diarrhea includes inflammatory bowel disease, malabsorption syndromes, irritable bowel disease, chronic parasitic infections, bacterial toxins, drugs and motility disorders. Plastron appendicitis is an abscess formation that occurs when the appendix is surrounded by the omentum following perforation of acute appendicitis. The cases usually present with abdominal pain, nausea, vomiting, and abdominal mass. Chronic diarrhea is a rare finding. In this study, we explore a case of a 63-year-old man who had diarrhea and intermittent abdominal pain for 3 months and underwent a diagnosis of plastron appendicitis as a result of the investigations.
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PMID:An unusual cause of chronic diarrhea: plastron appendicitis. 3094 23

Olmesartan's sprue-like enteropathy was first described in 2012 and typically presents with diarrhoea, weight loss, nausea, vomiting, low albumin and histological evidence of intestinal villous atrophy. Coeliac disease is one of the main differential diagnoses and should be excluded. We present the clinical case of a 63-year-old man treated with olmesartan for 10 years who presented with a 2-month history of diarrhoea and was diagnosed with olmesartan's enteropathy. This case highlights the need for clinical suspicion of this new entity in order to reduce the associated morbidity and unnecessary costly investigations.
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PMID:Olmesartan: A Little-Known Cause of Diarrhoea. 3141 Mar 55

A 77-year-old man with arterial hypertension and dyslipidaemia, treated with olmesartan/hydrochlorothiazide and simvastatin, was admitted with a 3-week history of anorexia, nausea, vomiting, profuse diarrhoea and weight loss. He was dehydrated and blood tests showed acute kidney injury. The aetiological study was inconclusive. The patient had a favourable clinical evolution during hospitalization and was discharged. However, after about 10 days at home, he was re-admitted to hospital with the same clinical presentation. It was noticed that olmesartan had not been prescribed during the previous admission but had been restarted on an outpatient basis. Biopsy examination showed duodenal mucosa with villous atrophy and polymorphic inflammatory infiltrate. Antibody testing for coeliac disease was negative. Based on these facts, it was hypothesized that the patient had olmesartan-induced enteropathy, which was subsequently confirmed.
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PMID:Olmesartan-Induced Enteropathy: A Case of Recurrent Diarrhoea. 3278 26


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