Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 86-year-old female patient is reported with myositis proliferans according to the criteria described by Enzinger and Dulcey (1967). This disease, first described by Kern (1960), impressed as a painful, firm and immovable tumor of almost 3 cm in size situated at the upper lip of our patient. Myositis proliferans can simulate a sarcoma, histologically and clinically; therefore, this disease shall be introduced to the dermatologic literature avoiding unnecessary invasive treatment. There is a relationship to fasciitis nodularis; a clinical and histological differentiation is possible as in our patient.
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PMID:[Proliferative myositis]. 686 86

Feline infectious peritonitis (FIP) is a fatal immune-mediated vasculitis of felids caused by a mutant form of a common feline enteric virus, feline enteric coronavirus. The virus can attack many organ systems and causes a broad range of signs, commonly including weight loss and fever. Regardless of presentation, FIP is ultimately fatal and often presents a diagnostic challenge. In May 2010, a malnourished young adult male mountain lion (Puma concolor) from Kern County, California, USA was euthanized because of concern for public safety, and a postmortem examination was performed. Gross necropsy and histopathologic examination revealed necrotizing, multifocal myocarditis; necrotizing, neutrophilic, and histiocytic myositis and vasculitis of the tunica muscularis layer of the small and large intestines; and embolic, multifocal, interstitial pneumonia. Feline coronavirus antigen was detected in both the heart and intestinal tissue by immunohistochemistry. A PCR for coronavirus performed on kidney tissue was positive, confirming a diagnosis of FIP. Although coronavirus infection has been documented in mountain lions by serology, this is the first confirmed report of FIP.
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PMID:Feline infectious peritonitis in a mountain lion (Puma concolor), California, USA. 2356 18