Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027121 (myositis)
4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anti-Mi-2 antibody directed against the protein complex of unknown function is considered an immunological marker of dermatomyositis. We detected this antibody in 7 among 72 patients, whose sera were investigated for the presence of myositis specific autoantibodies with the use of indirect immunofluorescence and double immunodiffusion. Six patients had dermatomyositis, and 1 had unclassified collagenosis. Detection of anti-Mi-2 antibody is very important for diagnosis because of its high specificity, and also for prognosis and therapy.
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PMID:[Anti-MI-2 antibody as a specific marker of dermatomyositis]. 858 96