Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

80 patients with soft tissue calcifications were treated. 24 patients suffered from myositis ossificans traumatica, 23 from calcific bursitis (Duplay's disease), 6 from osteoarthropathy of elbow joint after severe craniocerebral trauma, 9 from calcifications round elbow joint after local trauma, 13 from calcifications round hip joint, 5 from calcifications in ligaments and tendons. About 75 per cent patients were cured. Calcifications disappeared or substantially diminished. Very good functional improvement followed in affected joints. Patients were treated with new method: local application of MgSO4 into calcification area was used for 2-20 weeks, peroral administration of Mg lactate was given for 4-6 months. There were neither complications nor side effects of this treatment.
 ...
PMID:Treatment of soft tissue calcifications with magnesium. 183 78

Eighty patients with soft tissue calcification were treated: 24 suffered from myositis ossificans traumatica, 23 from calcific bursitis (Duplay's disease), six from osteoarthropathy of elbow joint after severe craniocerebral trauma, nine from calcification around the elbow joint after local trauma, 13 from calcification around the hip joint, and five from calcification in ligaments and tendons. Using a new method of treatment about 75% of patients were cured. Calcifications disappeared or diminished substantially. Very good functional improvement followed in affected joints. The treatment involved local application of MgSO4 under local anaesthesia into calcified areas for 2-20 weeks, together with peroral administration of Mg lactate for 4-6 months. There were no complications or side effects of this treatment.
 ...
PMID:Soft tissue calcification treated with local and oral magnesium therapy. 213 25

In a five-year investigation the authors demonstrate their results with Mg treatment in 54 patients with ectopic calcifications and ossifications. Based on the results of experimental work, where the inhibiting action of Mg ions on calcium phosphate precipitation was proved in vitro as well as in vivo, the authors treated by means of local MgSO4 injections and oral administration of Mg lactate 17 patients with ossifying myositis, 16 with calcareal bursitis, 4 patients with paraosteoarthropathy of the elbow after craniocerebral injuries, 6 calcifications of the hip joint after operations and 5 calcifications in the insertions of tendons and ligaments. In all instances diminution to complete disappearance of the calcificates and ossificates was observed. The authors achieved also very favourable functional results. In the majority of patients the mobility in adjacent joints was restored. Clinical experience indicates that Mg prevents the development or suppresses further growth of ectopic calcifications and ossifications. During the formation of the ossificate, which is still immature, Mg causes diminution and sometimes complete absorption of the immature bone.
 ...
PMID:[The importance of magnesium in orthopedics. VI. The importance of magnesium in the treatment of ectopic calcification and ossification]. 250 88