Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027121 (
myositis
)
4,538
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The authors describe a new canal syndrome, which they call the "superficial sural aponeurosis canal syndrome" or "sural nerve tunnel syndrome". Mostly seen in sportsmen, it was observed in this case in the context of a
myositis
ossificans circumscripta of the tendo-muscular junction of the heel. The clinical signs are caused by compression of the sural nerve where it passes through a nonextensible tunnel formed by the fold of the posterior sural aponeurosis. This is distinguished from a loge syndrome; the most typical clinical sign is increased
pain
in the territory of the sural nerve during plantar flexion of the ankle; in this position reduced sensory conduction velocity is measured. The treatment consists in a section of the fibro-aponeurotic arch.
...
PMID:[Syndrome of compression of the external saphenous nerve (or the sural nerve)]. 260 93
One hundred and twenty-three patients with human immunodeficiency virus infection have been referred to rheumatologists at our hospitals between October 1985 and April 1989 because of musculoskeletal symptoms. Thirty-four homosexual men presented with acute, peripheral, non-erosive arthritis (mean number of four joints affected) with the knees being involved in 23. Other features developing concurrently with arthritis included psoriasis, keratoderma blenorrhagica, plantar fasciitis, urethritis, conjunctivitis and anterior uveitis. Four of five patients investigated were HLA-B27-positive; none of 15 patients tested had raised titres of rheumatoid or antinuclear factors. Various infections were associated with the onset of arthritis and two patients with a recent history of diarrhoea had serological evidence of yersinia infection. No micro-organisms were identified within the joint except for HIV itself. At the time of onset of arthritis four of these individuals had the acquired immunodeficiency syndrome (AIDS); 11 were not known to be HIV-positive before testing which was performed following referral for arthritis. Six patients have since developed AIDS and four have died. In 15 individuals, including those who progressed to AIDS, joint symptoms have been severe, persistent and poorly responsive to non-steroidal anti-inflammatory drugs. In only five patients has the arthritis been known to resolve. Synovitis has also been seen in two women: in one of these HIV infection was thought to have been acquired through intravenous drug abuse. Other rheumatic lesions included myalgia/
myositis
, non-inflammatory peripheral arthritis, spinal
pain
, soft tissue lesions, arthralgia or myalgia of unknown cause and infective lesions including septic arthritis and bony infection due to histoplasmosis and atypical mycobacterial infection. It appears likely that HIV infection is a risk factor for the development of seronegative arthritis and other rheumatic lesions.
...
PMID:Rheumatological lesions in individuals with human immunodeficiency virus infection. 261 38
Thirty cases of tropical
myositis
, (22 suppurative, 8 non-suppurative) aged 11 to 65 years were seen in a period of one year. There were 22 males and 8 females. There was a total of 78 muscular lesions in 22 suppurative cases and 19 muscular lesions in 8 non-suppurative cases. The most common presentation was localised myalgia (100%), fever (96.7%) generalized myalgia (56.7%), arthralgia (40%),
pain
in abdomen (33.3%) and breathlessness (30%). Extramuscular complications were present in 50% cases. Twenty four muscle biopsies were taken. Sixteen showed changes of suppurative
myositis
i.e. non-specific acute inflammatory reaction, muscle necrosis with myocytolysis, vacuolation of cytoplasm and loss of striations. Cell mediated immunity was found to be suppressed in patients of non-suppurative
myositis
in comparison with the suppurative group. IgG, IgA and IgM were significantly raised in patients in comparison to controls (p less than 0.05). The intact humoral immunity indicates good response to acute phase reaction and increased levels of IgG, IgA and IgM (specially IgG) can be taken as good prognostic parameter.
...
PMID:Tropical myositis. A clinical immunological and histopathological study. 263 56
The second generation fibric acid derivative, bezafibrate (Bezalip, Norlip) is widely used as a hypolipemic agent throughout Europe and Israel. Its side-effects are well documented, and include
myositis
, which is considered very rare. We report a 55-year-old diabetic woman with hypertension who had mild renal dysfunction (creatinine 2.0 mg/dl) who received 400 mg/d bezafibrate because of combined (Type IIb) hyperlipoproteinemia. She developed acute
myositis
, with extreme muscle weakness,
pain
and CPK levels of up to 3500 units. On discontinuation of the drug all clinical and biochemical features ceased and complete cure followed. No other symptoms have appeared during 2 years of followup. The few reports of such cases in the German literature point to a greater prevalence of
myositis
in those with renal dysfunction. Early diagnosis of bezafibrate-induced
myositis
is crucial, a discontinuation of the drug results in cure.
...
PMID:[Acute severe myositis due to bezafibrate treatment]. 272 79
Myositis
caused by Clostridium septicum was diagnosed in a 3-year-old Doberman Pinscher. The illness was characterized by signs of
pain
, swelling, and lameness of left forelimb. Despite treatment, the dog died. Necropsy revealed crepitant swelling over the entire left forelimb, thoracic and abdominal wall, and lumbosacral area. Subcutaneous edema and black, emphysematous muscles also were found. Histologically, hemorrhages, congested vessels, and degeneration and necrosis of myofibers with scattered infiltration of neutrophils were seen in the affected muscles.
...
PMID:Clostridial myositis in a dog. 291 94
A 54-year-old man presented with gangrenous
myositis
caused by Streptococcus pyogenes. A review of the literature disclosed 10 similar cases. Their presenting manifestations were spontaneously occurring, localized, excruciating
pain
; mottling suggestive of ischemic changes; and signs of sepsis. The duration of illness ranged from two to six days, and the outcome was uniformly fatal. This rare but distinct entity resembles clostridial myonecrosis except that it lasts slightly longer and does not involve gaseous crepitus. A definitive diagnosis of myonecrosi scan be established by surgical exploration; early, radical debridement plus penicillin therapy should be undertaken after diagnosis in an attempt to alter the usual devastating outcome.
...
PMID:Spontaneous gangrenous myositis induced by Streptococcus pyogenes: case report and review of the literature. 329 2
Idiopathic acute orbital
myositis
is a subgroup of inflammatory orbital pseudotumor. The case of a 35 year-old woman who suffered a left ocular
pain
with eyelid swelling, conjunctival hyperemia and limitation of abduction of the left eye is reported. CT showed an enlargement of the left medial rectus muscle enhanced with contrast. The pathogenesis remained obscure. The evolution was favourable with corticosteroids.
...
PMID:[Acute idiopathic orbital myositis]. 334 8
A 56 year old male presented after 2 months of muscle stiffness,
pain
and palpable lumps. Biopsy confirmed the presence of
myositis
. Myasthenia gravis and peripheral neuropathy became clinically apparent within days of commencing corticosteroid therapy. 4 months later, at operation, a locally invasive thymoma was found. This combination of features has not previously been described.
...
PMID:A case of invasive thymoma associated with myasthenia gravis, myositis and demyelinating neuropathy. 358 2
Revision total hip replacement has traditionally required a trochanteric osteotomy for successful cement removal and component reinsertion. In this study the authors have concluded that in most instances the revision total hip replacement procedure can be successfully performed without trochanteric osteotomy. The advantages are underscored by the high percentage of trochanteric complications with trochanteric osteotomy for revision total hip replacement and the ease of rehabilitation without trochanteric osteotomy. Also, improved functional results without trochanteric osteotomy were noted. The specific indications for the procedure included revision total hip replacement with ununited prior trochanteric osteotomy, revision total hip replacement with femoral shaft fractures, and revision total hip replacement with stem fractures requiring only acetabular revision. The contraindications to the procedure are fibrous union or ununited trochanteric osteotomy from prior total hip replacement, severe acetabular protrusion of the acetabular component, advanced
myositis
ossificans, ankylosis of the hip, and advanced proximal femoral osteoporosis. The operating room records, x-rays, and outpatient records of 63 total hip revisions in 52 patients were reviewed. There was a minimum 2-year follow up with a range from two years to seven years. The patients were divided into two groups, comparing 21 trochanteric osteotomized revisions to 44 with trochanteric sparing techniques. Both groups were analyzed for age, type of implant, intraoperative perforation of femur, intraoperative femoral shaft fractures, intraoperative cortical window, component malpositioning extraneous cement, intraoperative blood loss, operating time, postoperative leg length inequality, persistent abductor weakness, average first day of ambulation, wound infection, dislocation, nonunion of the trochanter, and postoperative
pain
. In the nonosteotomized group, there was a 21% decreased blood loss, a 14% decrease in persistent abductor weakness, a 14% decrease in subluxation and dislocation, a 30% decrease operating time and a 50% reduction in intraoperative femoral perforation. In the osteotomized group there were six cases of fibrous union of the greater trochanter, two cases requiring removal of broken wires for trochanteric bursitis. A detailed surgical technique and representative cases are presented. In carefully selected cases, revision total hip replacement is optimally performed without trochanteric osteotomy. Postoperative trochanteric problems of nonunion, broken wires, bursitis, and abductor weakness can effectively be eliminated by avoiding trochanteric osteotomy.(ABSTRACT TRUNCATED AT 400 WORDS)
...
PMID:Revision total hip replacement without trochanteric osteotomy. 358 21
A 2-year-old boy had intermittent
pain
and mottling of the left thigh. Swelling of the vastus lateralis developed, and a biopsy revealed proliferative
myositis
. The pathogenesis is unknown, but trauma and ischemia have been implicated. The rarity of proliferative
myositis
in children, and the possibility of mistaking the lesion for a sarcoma make the case noteworthy.
...
PMID:Proliferative myositis in a two-year-old child. 360 19
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>