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Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Scleroderma can be accompanied by arthralgias, inflammatory arthritis, flexion contractures, nerve entrapment, myositis, or myopathy. Antibodies in scleroderma can occur in other connective tissue diseases; overlap syndromes between scleroderma and Sjogren's syndrome, lupus, and rheumatoid arthritis are reported. Many of the musculoskeletal symptoms in scleroderma are treated symptomatically; most treatments are not proven in randomized controlled trials in these patients. Musculoskeletal manifestations are a major cause of morbidity and disability in scleroderma.
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PMID:Musculoskeletal involvement in scleroderma. 1284 1

We describe a case of sciatic nerve entrapment neuropathy due to a posttraumatic heterotopic ossification (myositis ossificans traumatica). A 52 y.o. man was examined complaining from right lower limb pain and weakness progressing for one year after a blunt trauma and a hematoma of the hip. Clinical examination demonstrated sciatic nerve palsy with pain and paresthesia felt distal to the lesion. Electrodiagnostic studies show severe denervation changes in the tibialis anterior, extensor digitorum brevis and gastrocnemius muscles. Both radiography and CT scan revealed new bone formation in the soft tissue in the upper third of the hip. Surgical exploration discovered an osseous tunnel in the fascial plane between the semitendinous and biceps femoris muscles, encasing the sciatic nerve in a length of 12 cm. The lesion was hard and intimately associated with the epineuria. Histopathological examination of the lesion demonstrated mature, lamellar bone structure. Under optical magnification the ectopic bone was totally removed and decompression of the sciatic nerve was achieved. Nevertheless neurological recovery was absent at one year follow-up after surgery.
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PMID:[Sciatic xeuropathy secondary to compression by a heterotopic ossification due to myositis ossificans traumatica. (Case report and review of the literature)]. 2050 83