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Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of the nodular form of polymyositis is reported in which muscle necrosis and inflammation, and fibrosis of subcutaneous fat were observed. Although the patient had a short history, the presence of extensive fibrosis with acute lesions indicated that the disease had been present for some time. In addition to the nodular lesions, the patient had clinical, electrophysiological and pathological evidence of a more generalised myopathy. The subsequent development of a rash resembling that of vasculitis and a peripheral nerve lesion, suggested that the localised nodular myositis was associated with systemic vasculitis. Although immunoglobulin and complement deposits were not detected in blood vessel walls in muscle or skin, a positive reaction to intradermal injection of autologous serum suggested the presence of circulating immune complexes.
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PMID:The nodular form of polymyositis--a possible manifestation of vasculitis. 743 Nov 46

Orbital myositis is a subgroup of the nonspecific inflammatory syndrome or orbital pseudotumor and is characterized by a primary inflammation of extraocular muscles. The authors describe a 70-year-old patient with acute proptosis, ocular pain and right ophthalmoplegia, whose orbital computed tomographic scan showed enlargement of the homolateral extraocular muscles. Clinical presentation and complementary tests were compatible with the diagnosis of orbital myositis however, because of the particular aspects, which included retinal central vein occlusion, optic nerve lesion, distension of the superior ophthalmic vein and the homolateral cavernous sinus, the differential diagnosis with cavernous sinus pathology and thyroid ophthalmopathy was considered. The importance of a rapid diagnosis and treatment is stressed.
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PMID:[Orbital myositis]. 944 84