Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027121 (
myositis
)
4,538
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Plasma CK concentrations have been widely used as the primary muscle enzyme marker for diagnosis and progression of
myositis
. Recently, total CK and CK-MB serum concentrations have been compared to, and used in conjunction with, serum concentrations of aspartate aminotransferase in diagnosis of
myositis
. The algorithmic use of CK, AST, and aldolase plasma concentrations to diagnose and categorize patients with myopathy may be a useful method of diagnosing specific muscle disease without invasive procedures.
CAIII
, as a specific marker for skeletal muscle damage, may replace CK as the enzyme of choice in diagnosis and progression of
myositis
and other muscle disease. Additional studies are required to determine the usefulness of carbonic anhydrase for the diagnosis and assessment of
myositis
.
...
PMID:Evaluation of laboratory tests as a guide to diagnosis and therapy of myositis. 785 25
