Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Each year, at any age, children are at risk of influenza illness during the epidemics. Children, especially those at school (attack rate close to 30%), have a major role in viral dissemination. Most of influenza illnesses occur in healthy children. Manifestations are typical, as in adults, in children over 5 years of age and less specific in younger children explaining misdiagnosis and underestimation in the youngest. Respiratory complications in outpatients include acute otitis media (close to 30% in children less than 3 years of age) and pulmonary disease (5 up to 10%). High fever 240 degrees C is frequent. Febrile convulsions occur in about 20% of hospitalised children aged 6 month to 5 years. Other complications (encephalitis, myositis, myocarditis, etc.) are reported. Hospitalisation rate is a severity index. In children less than 5 years of age, it is as high as 500/100,000 when risk factors exist and 100/100,000 when absent. Influenza, which is a respiratory virus, is the only one for which both a vaccine and specific treatment (anti-neuraminidases) exist. They are detailed.
 ...
PMID:[Against influenza in children, which actions?]. 1513 43

Acute mastoiditis is the most common complication of acute otitis media (AOM) and its early recognition and management still poses a challenge due to potentially serious consequences. The incidences of extracranial and intracranial suppurative complications of AOM in children have decreased significantly, yet they remain a serious clinical problem, especially when caused by bacteria resistant to antibiotics. The authors presented a case of rare AOM complication - zygomatic abscess with temporal myositis. A 6-year-old boy was admitted to the ENT Department with 4 weeks of ear pain, treated for AOM with cefuroxime axetyl and amoxicilline, with acute mastoiditis and subsequent abscess formation in zygomatic and preauricular region. The inflammatory process spread through anterior air cells to the zygomatic cells leading to a fistula formation in the zygomatic bone and breakthrough into the temporal muscle. The surgical procedures applied were: myringotomy with drainage, cortical mastoidectomy and revision of zygomatic area and treatment with antibiotics (ceftriaxon). Enterococcus faecalis and Streptococcus viridans were found in the culture of middle ear and mastoid effusion. After half a year of follow-up the child had a normal hearing. Severe complications of AOM are rare today. An early diagnosis in order to promote adequate management and prevent inherently suppurative complications is essential.
 ...
PMID:Zygomatic abscess with temporal myositis - a rare extracranial complication of acute otitis media. 1576 97