Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027121 (myositis)
 4,538 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case of nutritional myopathy in a cat primarily caused by vitamin E deficiency is described. The animal which had been fed a diet consisting almost entirely of boiled Norwegian coley, was presented with swollen muscles in both the hind and fore legs. Sections of biopsy material revealed chronic, severe myositis, with normal muscle tissue undergoing a series of degenerative changes. Correct dietary management, with multivitamin and mineral supplementation, led to a complete clinical recovery, the cat regaining full use of its legs within 14 days.
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PMID:Nutritional myopathy in a cat. 713 70

We report a patient with late-onset celiac disease and neurological manifestations including myopathy, polyneuropathy, and ataxia. Laboratory investigations showed anti-gliadin antibodies and severe vitamin E deficiency. Muscle biopsy revealed inflammatory infiltrates and rimmed vacuoles, similar to those found in inclusion-body myositis. A gluten-free diet and vitamin E supplementation reversed both the clinical neurological manifestations and the abnormalities in the muscle biopsy. Anti-gliadin antibodies were no longer present. This case illustrates the spectrum of neurological complications of celiac disease and documents the occurrence of reversible pathology resembling inclusion-body myopathy in the muscle.
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PMID:Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease. 1538 48