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Query: UMLS:C0027066 (myoclonus)
 4,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a patient with palatal myoclonus the mutual interaction between voluntary movements and the myoclonic activity was analysed. Amplitude and frequency of myoclonic activity in hand muscles were modulated by flexions and extensions. A 1:1 relationship was found between EMG-bursts in hand muscles and palatal movements. A 1:2 relationship was found between eye and finger movements. Resetting of myoclonus in the abductor digiti minimi muscle occurred after cutaneous ulnar nerve stimulation. It is suggested that feedback plays an important role in the generation of the oscillatory activity in PM in addition to pacemaker activity in brainstem neurons.
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PMID:Oscillatory activity in different motor subsystems in palatal myoclonus. A case report. 141 29

Case-1: A 4 month old, 7120 g, girl with hydrocephalus underwent endoscopic fenestration of the septum pellucidum. Her development had been normal without signs or symptoms of intracranial hypertension. She had no history of convulsion or apnea. Ventriculoscopic diagnosis was complete obstruction of the right foramen of Monro and partial defect of right ependyma. Intraoperative course was uneventful under general anesthesia. She had two episodes of respiratory arrest accompanied with myoclonus and the left conjugate deviation 15 min after extubation. Postoperative CT scan showed no abnormal findings such as intracranial hemorrhage. The respiratory arrest and conjugate deviation disappeared after phenobarbital administration. She had no further respiratory arrest. Case-2: A 1-month old boy with congenital hydrocephalus underwent endoscopic third ventriculostomy. He had no signs or symptoms of intracranial hypertension. CT scan showed enlargement of lateral ventricle and third ventricle due to aqueductal stenosis. Respiratory arrest was noted 10 min after extubation in the recovery room. His anterior fontanel sank abnormally and rigidity of the extremities was observed. His trachea was reintubated and he was transferred to ICU. After 24 h of respiratory care in the ICU he was extubated and discharged to the ward. He had no further episodes of respiratory arrest. We believe that postanesthetic apnea monitoring is mandatory in young infants who undergo ventriculoscopic surgery.
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PMID:[Respiratory arrest after a ventriculoscopic surgery in infants: two case reports]. 909 21

A 1-year, 8-month-old Rhodesian Ridgeback was presented with obtundation, ambulatory tetraparesis, and myoclonus. Initial clinical findings included ionized hypercalcemia with an apparent marked increase in parathyroid hormone, thrombocytopenia, and nonregenerative anemia. Low numbers of circulating atypical cells were noted on blood film evaluation. Brain magnetic resonance imaging identified an extra-axial contrast enhancing subtentorial lesion, and cerebrospinal fluid (CSF) analysis documented a marked atypical lymphocytic pleocytosis. Flow cytometry performed on the CSF demonstrated expression of only CD45, CD90, and MHC class II, with Pax5 positivity on subsequent immunohistochemistry. The final diagnosis was of B-cell lymphoblastic lymphoma or acute leukemia, given the distribution of disease and the presence of significant bone marrow infiltration alongside an aggressive clinical course. The unusual immunophenotype of the neoplastic cells and hypercalcemia presented antemortem diagnostic challenges, highlighting the need for a multidisciplinary approach and caution in the interpretation of clinical abnormalities in cases with multiple comorbidities.
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PMID:Myoclonus and hypercalcemia in a dog with poorly differentiated lymphoproliferative neoplasia. 3056 Oct 32