Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027066 (myoclonus)
4,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Objective tinnitus is often caused by palatal myoclonus. We report a 15 years old boy with objective tinnitus in both ears and palatal myoclonus. He had myorhythmic movements of both tensor veli palatini muscles asynchronous with the objective tinnitus. The frequency of the clonus was 120 contractions a minute. The myoclonus and the objective tinnitus disappeared after division of the bilateral tensor veli palatini muscles.
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PMID:[Objective tinnitus caused by myoclonus of the musculus tensor veli palitini]. 397 49

Objective tinnitus is a rather rare condition that may be due to myoclonus of certain muscles, such as the palate, or to arteriovenous communications, either congenital or acquired. In cases of palatal myoclonus the diagnosis of the causative factor is not always easy, but the use of tympanometry, EMG, and EEG may help in establishing the diagnosis. In cases of arteriovenous communications a pulse synchronous tinnitus is present. It may be temporarily obliterated by applying pressure over the mastoid area or over the carotid artery on the affected side. Audiometric and tympanometric studies are not diagnostic, and very careful angiographic studies are necessary because routine tests may not show the lesion. The case presented suggests another etiologic possibility for vascular objective tinnitus: a stenosis of certain branches of the external carotid artery. The treatment for myoclonic causes of objective tinnitus has been for the most part unsatisfactory, whether it be medical or surgical. On the other hand, surgical treatment of arteriovenous communications results in complete amelioration of signs and symptoms--hence the necessity for an accurate diagnosis.
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PMID:Objective tinnitus: a case report. 685 39

Objective tinnitus may be caused by many etiologies-palatal myoclonus being one of them. We report one patient of voluntary palatal myoclonus presenting with objective tinnitus treated with botulinum toxin injection. Five units of botulinum toxin A were injected into each side of the soft palate at the palatal muscles (levator veli palatini and tensor veli palatini muscle). The tinnitus disappeared within two days of injection and no side effect was observed.
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PMID:Botulinum toxin injection for objective tinnitus from palatal myoclonus: a case report. 1211 33

Tinnitus is a common otological symptom. Usually it is subjective (perceived only by the patient); very rarely is it objective (heard by both the patient and the examiner) Objective tinnitus due to middle-ear myoclonus is extremely rare, with only a few case reports published in the literature. We present three cases of objective tinnitus caused by middle-ear myoclonus. All patients were cured by tympanotomy with stapedial and tensor tympani tendon section.
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PMID:Bilateral tinnitus due to middle-ear myoclonus. 1476 31

Subjective tinnitus (heard only by the patient) is a common otological complaint. Objective tinnitus (heard by the examiner as well as the patient) is extremely rare. There are only a few cases of objective tinnitus, secondary to middle-ear myoclonus, described in the literature. We present the case of a child with bilateral, congenital, objective tinnitus, secondary to middle-ear myoclonus, with otherwise normal hearing thresholds (250 Hz-8 kHz), and with no evidence of intra-cerebral or systemic disorders. No similar case has been reported in the world literature.
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PMID:Bilateral objective tinnitus secondary to congenital middle-ear myoclonus. 1599 81

Palatal myoclonus is an uncommon, rhythmic, "shock-like" involuntary movement of the muscles of the soft palate, throat, and other structures derived from the branchial arcs. Objective tinnitus is frequently neglected in review articles about childhood tinnitus. Our aim was to present the case of a 7-year-old girl with bilateral objective tinnitus due to palatal myoclonus without hearing impairment (normal hearing thresholds between 250 Hz and 8 kHz) but with otherwise normal hearing thresholds (250 Hz-8 kHz) and no evidence of intracerebral or systemic disorders. No treatment was useful.
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PMID:Objective tinnitus associated with essential palatal myoclonus: report in a child. 1822 97

Objective tinnitus can have many different etiologies, palatal myoclonus being one of the less frequent. This type of tinnitus is generated by involuntary rhythmic contraction of the soft palate, which generates an audible click for the patient and for the explorer. Botulinum toxin achieves temporary muscle paralysis through presynaptic inhibition of the acetylcholine level at the neuromuscular union. We present a patient with long-term objective tinnitus, along with this patient's response to botulinum toxin injection.
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PMID:Objective tinnitus from palatal myoclonus. Use of botulinum toxin: a case report. 2151 7

Objective tinnitus refers to a tinnitus that can also be heard by the examiner. It is a relatively rare condition, and can be misdiagnosed or neglected. Some causes of objective tinnitus are head and neck vascular malformations, or muscular myoclonus of the tensor tympani, stapedial, or palatal muscles. The case of an 11-year-old girl with an objective tinnitus lasting from 1 year is herein presented, and the diagnostic workup performed in this unusual case is described.
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PMID:A clockwork ear. 2271 Dec 31

Pulsatile tinnitus (PT) is relatively rare, which accounts for approximately 4% of patients with tinnitus. It originates from mostly vascular structures within the cranial cavity, head and neck region or thoracic cavity, and is transmitted to the cochlear by bony or vascular structures and the blood flow, stimulating patient's hearing. It can be the patient's subjective feelings, there can be objective performance.Vascular PT is more common than non-vascular PT. Vascular PT can be further classified by vessel of origin as arterial and venous ones, and the latter is more commonly seen clinically.It's rhythm is synchronous with patients' pulse, and its tinnitus frequency is less than 600 Hz. The cause of pulsatile tinnitus is complex and diverse, and 56 cases are reported in the literature. Objective tinnitus or somatosensory, associated with tympanic membrane myoclonus, ear blood flow changes adjacent to blood vessels and other in vivo factors. While subjective tinnitus lacks a clear source of the body. PT's pathogenesis has not been fully understood yet, so intensive study targeting PT is of great importance. This review focuses on the pathophysiological mechanisms,etiology,clinical manifestation, diagnosis and progress of treatment of vascular PT.
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PMID:[Research progress of vascular pulsatile tinnitus]. 2979 5

Objective tinnitus is a known but rare otologic symptom. This is a case report about a six-year-old boy, who was referred to a hearing clinic for further investigation of an audible clicking sound. He experienced clicking sounds, and his parents were able to hear the sounds when listening nearby. This objective tinnitus is caused by myoclonus of either the m. tensor tympani or the m. stapedius. We discuss methods to evaluate objective tinnitus including the clinical use of a stethoscope and also the possibility of using impedance measuring in patients with objective tinnitus.
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PMID:[Objective tinnitus]. 3025 31


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