Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026986 (
myelodysplastic syndrome
)
14,926
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MDS
2225
AML
1096
Sep
909
erythroid
857
HLA
518
p53
469
CD34
465
FAB
448
lymphoid
422
hemoglobin
409
erythropoietin
408
granulocyte
310
granulocyte colony-stimulating factor
289
Mol
288
cytokine
268
RUNX1
245
TET2
220
ASXL1
206
CML
201
ALL
200
G-CSF
190
She
189
non-Hodgkin's lymphoma
183
ferritin
177
SF3B1
176
FLT3
172
JAK2
168
RARS
163
FISH
163
GM-CSF
156
CSF
152
MPN
145
histone
145
DNMT3A
143
megakaryocyte
137
granulocyte-macrophage colony-stimulating factor
128
DNA methyltransferase
125
CD33
117
histone deacetylase
117
MLL
115
tyrosine kinase
111
interferon
109
GATA2
108
SCT
107
myeloperoxidase
107
AML1
107
CD4
103
p13
102
telomeric
99
thrombopoietin
98
EZH2
98
CD13
98
granulocyte-macrophage
95
CD8
94
cryptic
94
NPM1
94
p15
93
tumor necrosis factor
90
NRAS
89
U2AF1
87
all-trans
84
HLA-DR
83
TEL
82
IDH1
82
CD45
80
human leukocyte antigen
78
WT1
76
IL-3
75
Erythropoietin
73
IDH2
69
c-kit
67
hematopoietic stem and progenitor cells
67
p21
66
CD117
66
ara
65
caspase-3
65
transferrin receptor
64
ras
64
p11
64
macrophage colony-stimulating factor
64
more...
Disease
myelodysplastic syndrome
14926
acute myeloid leukemia
5398
cancer
3326
leukemia
3171
MDS
2225
anemia
1408
tumor
1097
lymphoma
1034
chronic myeloid leukemia
948
acute leukemia
929
aplastic anemia
829
refractory anemia
789
Leukemia
724
chronic myelomonocytic leukemia
714
thrombocytopenia
704
acute lymphoblastic leukemia
688
graft-versus-host disease
673
dysplasia
665
myeloproliferative disorders
586
multiple myeloma
578
RAEB
571
hematologic malignancies
535
pancytopenia
505
neutropenia
502
Hodgkin's disease
357
trisomy 8
298
chronic lymphocytic leukemia
275
iron overload
273
RARS
258
leukemogenesis
251
non-Hodgkin's lymphoma
238
myelofibrosis
237
secondary AML
236
chronic lymphocytic leukemia
216
acute nonlymphocytic leukemia
208
paroxysmal nocturnal hemoglobinuria
192
myeloid leukemia
183
polycythemia vera
175
thrombocytosis
171
AML/MDS
163
Parkinson's disease
159
RAEB-T
155
MAR
153
refractory cytopenia with multilineage dysplasia
147
primary myelofibrosis
144
pneumonia
142
blast crisis
139
minimal residual disease
138
acute promyelocytic leukemia
138
myelosuppression
135
Fanconi
133
lymphoblastic leukemia
132
sepsis
130
trisomy
129
essential thrombocythemia
126
thalassemia
124
breast cancer
124
immunodeficiency
123
sarcoma
113
sepsis
110
juvenile myelomonocytic leukemia
109
SCT
107
WT1
106
tumorigenesis
105
Down syndrome
100
carcinoma
98
Best
97
vasculitis
96
eosinophilia
95
leukopenia
94
erythroleukemia
85
Sweet
83
chloroma
83
lymphoproliferative disorders
80
fungal infection
79
macrocytic anemia
78
AIDS
77
HIV
76
severe congenital neutropenia
75
diabetes
73
more...
Symptom
fatigue
138
splenomegaly
123
diarrhea
87
nausea
64
pain
63
dyspnea
53
vomiting
47
hepatosplenomegaly
42
weakness
40
abdominal pain
35
cough
33
bone pain
31
headache
30
erythema
29
anorexia
27
constipation
24
seizures
22
tremor
21
discomfort
21
exhaustion
18
Ill
18
nausea and vomiting
17
bradykinesia
16
chest pain
15
hepatomegaly
15
respiratory distress
15
discomfort
15
sleepiness
15
arthralgia
15
anesthesia
15
shortness of breath
14
fever of unknown origin
13
pallor
13
myalgia
13
chills
12
dizziness
11
lethargy
11
ataxia
11
exertional dyspnea
10
motor symptom
10
back pain
10
night sweats
8
spasticity
7
cachexia
7
polyuria
7
asthenia
7
syncope
6
dystonia
6
apathy
6
enuresis
5
hemoptysis
5
rigors
5
hypotonia
5
low back pain
4
collapse
4
hemiplegia
4
flushing
4
polydipsia
4
paraparesis
4
dysuria
4
angina
4
paresis
4
overweight
4
dysarthria
4
paresthesia
4
epigastric pain
3
spasm
3
myoclonus
3
dry skin
3
decreased appetite
3
starvation
3
nasal congestion
3
insomnia
3
agitation
3
distraction
2
pachyonychia
2
lightheadedness
2
consciousness disturbance
2
acute abdomen
2
right upper quadrant pain
2
more...
Drug
MDS
2225
CSF
279
G-CSF
192
Lenalidomide
164
Dermatol
121
Deferasirox
39
MRC
37
lysine
33
Azacytidine
30
TEL
30
Fludarabine
27
AraC
27
Amifostine
25
IL-2
24
Leaf
24
Posaconazole
21
anti-CD33
21
TRM
20
Clofarabine
19
Revlimid
19
ROS
17
CTX
17
Dacogen
16
TTC
14
IFN-gamma
14
Arsenic trioxide
14
Cardiovasc
14
ROC
12
ARA-C
11
Etoposide
11
Epoetin
10
Vitamin K2
9
Rituximab
9
Campath
9
Imatinib
9
Tipifarnib
9
Campath
9
Bortezomib
9
Antithymocyte globulin
8
Tacrolimus
8
Spectrum
8
ascorbate
8
Filgrastim
8
Prednisolone
8
Gleevec
7
Infliximab
7
Infliximab
7
Ethyol
7
Filgrastim
7
Glutathione
7
Idarubicin
7
Erlotinib
6
Epoetin alfa
6
LCM
6
LCM
6
ETS
6
Fluconazole
6
Prednisone
5
ENT
5
NBT
5
CTX
5
IL-11
5
Lonafarnib
5
Epoetin alfa
5
TMS
5
DBS
5
CTX
5
Monit
5
Heme
4
Bexxar
4
AZT
4
BLM
4
p75
4
Darbepoetin alfa
4
Spectrum
4
Dial
4
AZT
4
Midostaurin
4
Zevalin
4
Adriamycin
4
more...
Enzyme
ERK
311
focal adhesion kinase
266
peroxidase
144
DNA methyltransferase
126
topoisomerase
126
topoisomerase
117
BMT
107
CD13
98
mitogen-activated protein kinase
63
reverse transcriptase
59
lactate dehydrogenase
51
alkaline phosphatase
51
protein kinase
46
caspase-3
45
lysozyme
39
CD10
37
proteasome
32
P-glycoprotein
30
farnesyltransferase
23
farnesyltransferase
23
tryptase
21
trypsin
21
phosphoglycerate kinase
21
RNA polymerase
20
STR
18
neutrophil elastase
18
NOS
18
TdT
16
alanine aminotransferase
16
isocitrate dehydrogenase
16
NQO1
15
glutathione S-transferase
15
isocitrate dehydrogenase
15
MEK
14
MDR
14
thyroid peroxidase
13
phospholipase C
13
thrombin
13
granzyme B
13
demethylase
12
protein kinase C
12
aspartate aminotransferase
12
PARP
12
calcineurin
12
ribonucleotide reductase
11
ribonucleotide reductase
11
luciferase
11
APC
11
transcriptase
11
cytidine deaminase
10
ACE
9
phosphatidylinositol 3-kinase
9
endonuclease
8
ferrochelatase
8
caspase-1
8
aldehyde dehydrogenase
8
elastase
7
DNA polymerase
7
glucose-6-phosphate dehydrogenase
7
caspase-8
7
histone acetyltransferase
7
AMP-activated protein kinase
7
gamma-glutamyl transpeptidase
6
NADPH oxidase
6
AMPK
6
caspase-9
6
creatine kinase
6
asparaginase
6
ATPase
6
PI-PLC
6
hypoxanthine-guanine phosphoribosyltransferase
6
acid phosphatase
6
catalase
6
ALA synthase
6
ceruloplasmin
5
NADPH oxidase
5
ricin
5
histone demethylase
5
thymidine kinase
5
plasmin
5
more...
Compound
DNA
1302
Clin
1046
Dec
1024
iron
458
retinoic acid
157
5-Azacytidine
144
Ara-C
144
oxygen
129
Ara-C
121
5-Aza-2'-deoxycytidine
96
His
89
water
69
benzene
63
BCR
63
tyrosine
62
DAC
56
TBI
52
acetate
50
ABL
49
Neo
48
creatinine
47
TNF
46
lysine
43
sodium
39
copper
38
calcium
36
zinc
32
VP-16
32
TEL
30
Hemoglobin
30
serine
27
iodine
25
Cyclosporine
24
phosphate
24
GTP
24
Amifostine
24
Optimal
24
MTT
23
ATP
23
DFS
23
pyrimidine
22
pyrimidine
22
vitamin D
21
PDQ
19
INT
19
glucose
19
Busulfan
19
arginine
18
CPT
18
ammonium
18
Benzene
17
CTX
17
ADP
16
Pac
16
cysteine
15
nitrogen
15
hydrogen
15
ITP
15
Topotecan
14
ADP
14
methanol
14
ADP
14
MEK
14
Topotecan
14
Hydroxyurea
14
acetonitrile
14
ethanol
14
MDR
14
DFO
14
alanine
13
Phe
13
PEG
13
dUTP
13
leucine
13
FK506
13
TEM
12
PEG
12
Methotrexate
12
hydroxyglutarate
12
Asp
12
more...