Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026986 (myelodysplastic syndrome)
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Human Gene/Protein
140 AA 11.1
granzyme B variant 11.1
MDS 11.1
C5orf4 11.1
KIP 2 11.1
C5orf3 11.1
MLF1IP protein 11.1
FAM160B2 11.1
EMID1 11.1
OR51D1 11.1
C9orf43 11.1
ZBTB38 protein 11.1
phosphoprotein regulated by mitogenic pathways 11.1
HSPA9 protein 11.1
C6orf80 11.1
HDACL1 11.1
U2 small nuclear RNA auxiliary factor 1 11.1
PP2135 11.1
RARS 10.9
ZRSR2 10.7
additional sex combs like 1 10.4
ASXL1 protein 10.4
LUC7L2 10.3
chemokine (C-C motif) receptor 4 10.1
teashirt zinc finger homeobox 2 10.1
Dedicator of cytokinesis 4 10.1
ALL1-fused gene from chromosome 1q 10.1
MLL-MAML2 10.1
H4FN 10.1
HLA class II DRB1 antigen 10.1
WD repeat and FYVE domain containing 3 10.1
ankyrin repeat domain-containing protein 26 10.1
PURG-A 10.1
U2AF1 10.0
SET binding protein 1 9.9
SAMD9L 9.9
GSD1b 9.7
myeloid leukemia factor 1 9.6
SF3B1 9.6
AML1/MDS1 9.6
more...
Disease
myelodysplastic syndrome 11.1
MLSM7 11.1
5q minus myelodysplastic syndrome 11.1
Leukemia secondary 11.1
Myelodysplastic Syndrome 11.1
Preleukemia 11.1
RCMD-RS 11.1
MDS-U 11.1
Refractory anemia with excess blasts-2 11.1
Myeloblastic leukemia with maturation 11.1
refractory cytopenia with multilineage dysplasia 11.0
MDS 10.9
RAEB-1 10.9
RAEB-2 10.9
AML/MDS 10.9
de novo myelodysplastic syndromes 10.9
ATMDS 10.9
RARS 10.9
RAEB 10.8
RAEB-T 10.8
Therapy-related myelodysplastic syndrome 10.8
Acquired sideroblastic anemia 10.6
Marrow dysplasia 10.6
MDS/MPD 10.6
refractory anemia 10.5
secondary myelodysplastic syndromes 10.5
MDS/MPD-U 10.5
sideroblastosis 10.3
chronic myelomonocytic leukemia 10.1
runner's anemia 10.1
Other anaemias 10.1
Oral papillomatosis 10.1
Acute myeloid leukemia with multilineage dysplasia 10.1
Megakaryocytic hypoplasia 10.1
FAB type M5a 10.1
CMML-2 9.8
ataxia-pancytopenia syndrome 9.7
secondary AML 9.7
atypical chronic myeloid leukemia 9.6
FPD/AML 9.5
more...
Symptom
swollen penis 7.7
diminished hearing 5.9
ENT symptoms 5.6
motor symptom 5.5
Rest tremor 5.3
polymyalgia 5.2
splenomegaly 4.7
Hyperekplexia 4.7
stuffy nose 4.6
Spotting 4.6
pachyonychia 4.5
bone pain 4.4
hepatosplenomegaly 4.3
dark urine 3.9
bradykinesia 3.9
night sweats 3.8
fever of unknown origin 3.7
rigors 3.7
Neurologic symptoms 3.5
pallor 3.5
bradypnea 3.4
ACHE 3.2
lightheadedness 3.1
non-productive cough 2.9
lassitude 2.9
Stepping 2.8
autodigestion 2.8
No adverse effect 2.7
enuresis 2.7
leg edema 2.7
dry skin 2.7
exertional dyspnea 2.6
right upper quadrant pain 2.6
chills 2.6
hangover 2.6
nausea 2.5
shortness of breath 2.5
fatigue 2.5
nasal congestion 2.5
asthenia 2.5
more...
Drug
MDS 11.1
Dacogen 10.6
Starasid 10.1
Azacytidine 9.4
Tandutinib 9.3
Revlimid 9.2
Lenalidomide 9.1
Deferasirox 8.7
Sobuzoxane 8.5
Ranimustine 8.3
Busulfex 8.3
Clofarabine 8.2
Lonafarnib 8.2
Tipifarnib 8.1
Rubitecan 8.1
Zemplar 7.5
Ilmofosine 7.4
Alvocidib 7.3
Amifostine 7.2
Roquinimex 7.2
Ethyol 7.1
Midostaurin 7.1
Antithymocyte globulin 7.1
anti-CD33 7.1
Vitamin K2 7.0
Fludarabine 6.9
Posaconazole 6.9
Bexxar 6.9
TRM 6.8
CFPM 6.7
Roferon A 6.7
ARA-C 6.7
Forodesine 6.5
Zebularine 6.5
TEL 6.4
Lenograstim 6.3
Istradefylline 6.3
Epoetin 6.3
G-CSF 6.3
Sodium phenylbutyrate 6.3
more...
Enzyme
BMT 6.4
CD13 5.9
DNA methyltransferase 5.8
STK4 5.6
cholesterol 25-hydroxylase 5.6
farnesyltransferase 5.6
deoxyguanosine kinase 5.5
farnesyltransferase 5.0
topoisomerase 4.8
topoisomerase 4.8
isovaleryl-CoA dehydrogenase 4.5
cancer procoagulant 4.5
PI-PLC 4.5
cytidine deaminase 4.4
PFI 4.4
phosphoglycerate kinase 4.4
ferrochelatase 4.2
TdT 4.2
CTP synthase 4.1
CYP7B1 4.1
riboflavin kinase 4.0
tryptase 4.0
MTD 3.8
oxoglutarate dehydrogenase 3.7
focal adhesion kinase 3.7
separase 3.7
ALA synthase 3.6
TGT 3.6
dCMP deaminase 3.6
deoxycytidine kinase 3.6
STR 3.6
cystathionine gamma-synthase 3.6
histone demethylase 3.5
CDH 3.5
isocitrate dehydrogenase 3.4
isocitrate dehydrogenase 3.3
neutrophil elastase 3.2
iduronate-2-sulfatase 3.2
thyroid peroxidase 3.2
pantothenate kinase 3.1
more...
Compound
5-Azacytidine 9.5
6-chloronicotinamide 9.1
Pipobroman 9.1
6-chloronicotinamide 9.1
3-fluorobenzamide 9.1
5-Aza-2'-deoxycytidine 8.4
Conessine 7.7
Casuarinin 7.7
DAC 7.7
MDMS 7.6
Homoharringtonine 7.5
Ara-C 7.4
Ara-C 7.2
Amifostine 7.1
Erythrocin 7.1
4 PA 6.9
2,2,4-trimethyl-1,2-dihydroquinoline 6.9
2-hydroxybenzohydrazide 6.7
13-cis-Retinoic acid 6.6
PDQ 6.6
TEL 6.3
Busulfan 6.3
Reticulin 6.3
Topotecan 6.2
2-naphthalenesulfonic acid 6.2
Cefozopran 6.2
PELS 5.9
K 10 5.9
Geranylgeraniol 5.9
URP 5.9
FXM 5.8
HMBA 5.7
Methylxanthine 5.7
Topotecan 5.7
INT 5.6
Oxindole 5.5
PPBP 5.5
RUB 5.4
TBI 5.4
Tetrahydrouridine 5.4
more...