Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026986 (myelodysplastic syndrome)
 14,926 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MDS 2225
AML 1096
Sep 909
erythroid 857
HLA 518
p53 469
CD34 465
FAB 448
lymphoid 422
hemoglobin 409
erythropoietin 408
granulocyte 310
granulocyte colony-stimulating factor 289
Mol 288
cytokine 268
RUNX1 245
TET2 220
ASXL1 206
CML 201
ALL 200
G-CSF 190
She 189
non-Hodgkin's lymphoma 183
ferritin 177
SF3B1 176
FLT3 172
JAK2 168
FISH 163
RARS 163
GM-CSF 156
CSF 152
histone 145
MPN 145
DNMT3A 143
megakaryocyte 137
granulocyte-macrophage colony-stimulating factor 128
DNA methyltransferase 125
CD33 117
histone deacetylase 117
MLL 115
tyrosine kinase 111
interferon 109
GATA2 108
myeloperoxidase 107
SCT 107
AML1 107
CD4 103
p13 102
telomeric 99
thrombopoietin 98
EZH2 98
CD13 98
granulocyte-macrophage 95
CD8 94
NPM1 94
cryptic 94
p15 93
tumor necrosis factor 90
NRAS 89
U2AF1 87
all-trans 84
HLA-DR 83
TEL 82
IDH1 82
CD45 80
human leukocyte antigen 78
WT1 76
IL-3 75
Erythropoietin 73
IDH2 69
c-kit 67
hematopoietic stem and progenitor cells 67
p21 66
CD117 66
caspase-3 65
ara 65
ras 64
EVI1 64
p11 64
transferrin receptor 64
macrophage colony-stimulating factor 64
CD56 63
BCR 63
transcobalamin II 62
c-fms 61
IL-6 60
CEBPA 58
N-ras 58
CD19 56
NUP98 56
DAC 56
CD38 55
B12 54
CD11b 53
collagen 52
CD15 52
NHL 51
RPS14 51
alkaline phosphatase 51
CD7 50
transferrin 50
IFN 50
ABL 49
stem cell factor 48
p10 48
CD14 48
splicing factor 47
TNF 46
proto-oncogene 46
EPO 46
vascular endothelial growth factor 45
lactate dehydrogenase 45
X-linked 45
Fas 45
mast cell 44
HLA-A 43
fused 43
KIT 42
CBL 42
MPL 42
Interleukin-3 42
esterase 41
peroxidase 41
X-chromosome 41
WT1) 41
TNF-alpha 41
ZRSR2 40
KRAS 40
LDH 40
Bcl-2 40
CLL 39
lysozyme 37
MRC 37
bcr 37
Pol 37
MRI 37
CD20 36
CR1 36
glycoprotein 36
Y chromosome 35
granulocyte colony stimulating factor 35
tumour suppressor 35
CD10 35
thrombopoietin receptor 35
MYC 34
CD16 33
chronic renal failure 33
chromosome 21 33
PTPN11 33
GPIIIa 32
DNMT1 32
p23 32
CD59 32
MPD 32
BCR-ABL1 32
p16 31
G-CSF receptor 31
proteasome 31
MAPK 31
ETO 30
more...
Disease
myelodysplastic syndrome 14926
acute myeloid leukemia 5398
cancer 3326
leukemia 3171
MDS 2225
anemia 1408
tumor 1097
lymphoma 1034
chronic myeloid leukemia 948
acute leukemia 929
aplastic anemia 829
refractory anemia 789
Leukemia 724
chronic myelomonocytic leukemia 714
thrombocytopenia 704
acute lymphoblastic leukemia 688
graft-versus-host disease 673
dysplasia 665
myeloproliferative disorders 586
multiple myeloma 578
RAEB 571
hematologic malignancies 535
pancytopenia 505
neutropenia 502
Hodgkin's disease 357
trisomy 8 298
chronic lymphocytic leukemia 275
iron overload 273
RARS 258
leukemogenesis 251
non-Hodgkin's lymphoma 238
myelofibrosis 237
secondary AML 236
chronic lymphocytic leukemia 216
acute nonlymphocytic leukemia 208
paroxysmal nocturnal hemoglobinuria 192
myeloid leukemia 183
polycythemia vera 175
thrombocytosis 171
AML/MDS 163
Parkinson's disease 159
RAEB-T 155
MAR 153
refractory cytopenia with multilineage dysplasia 147
primary myelofibrosis 144
pneumonia 142
blast crisis 139
minimal residual disease 138
acute promyelocytic leukemia 138
myelosuppression 135
Fanconi 133
lymphoblastic leukemia 132
sepsis 130
trisomy 129
essential thrombocythemia 126
breast cancer 124
thalassemia 124
immunodeficiency 123
sarcoma 113
sepsis 110
juvenile myelomonocytic leukemia 109
SCT 107
WT1 106
tumorigenesis 105
Down syndrome 100
carcinoma 98
Best 97
vasculitis 96
eosinophilia 95
leukopenia 94
erythroleukemia 85
Sweet 83
chloroma 83
lymphoproliferative disorders 80
fungal infection 79
macrocytic anemia 78
AIDS 77
HIV 76
severe congenital neutropenia 75
diabetes 73
sideroblastic anemia 72
hemolytic anemia 71
chronic myeloproliferative disorders 71
B-cell lymphoma 70
movement disorder 69
rash 68
idiopathic thrombocytopenic purpura 67
infectious diseases 66
aspergillosis 66
rheumatoid arthritis 65
mastocytosis 65
agranulocytosis 65
SDS 64
solid tumor 63
cytomegalovirus 61
DBA 60
sickle cell disease 58
megaloblastic anemia 57
dyskeratosis congenita 56
incontinence 55
renal failure 54
NHL 53
skin disease 53
follicular lymphoma 53
lung cancer 51
systemic lupus erythematosus 51
lymphadenopathy 49
ABL 49
iron deficiency anemia 49
depression 48
RAEB-2 47
thrombocytopenic purpura 46
iron deficiency 45
RAEB-1 45
atypical chronic myeloid leukemia 44
Infection 43
melanoma 43
Myelodysplastic Syndrome 43
Epstein 42
chronic leukemia 42
carcinogenesis 42
arthritis 42
pyoderma gangrenosum 41
macroglobulinemia 40
platelet disorder 40
tuberculosis 40
rare disease 40
Acute graft-versus-host disease 39
chronic renal failure 38
incontinence 38
prostate cancer 38
autoimmune disease 37
MDS/MPD 37
neurogenic bladder 37
ovarian cancer 37
tumor progression 36
interstitial pneumonia 35
thalassemia major 35
cirrhosis 34
polychondritis 34
hairy cell leukemia 33
Fanconi syndrome 33
lymphedema 33
metastases 32
autoimmune hemolytic anemia 32
hepatocellular carcinoma 32
influenza 32
hemochromatosis 30
Mycobacterium 30
residual disease 30
veno-occlusive disease 30
hypertension 30
Syndrome 29
mucormycosis 29
gammopathy 29
Crohn's disease 29
neuroblastoma 28
squamous cell carcinoma 28
virus infection 28
colon cancer 27
more...
Symptom
fatigue 138
splenomegaly 123
diarrhea 87
nausea 64
pain 63
dyspnea 53
vomiting 47
hepatosplenomegaly 42
weakness 40
abdominal pain 35
cough 33
bone pain 31
headache 30
erythema 29
anorexia 27
constipation 24
seizures 22
discomfort 21
tremor 21
exhaustion 18
Ill 18
nausea and vomiting 17
bradykinesia 16
discomfort 15
arthralgia 15
chest pain 15
hepatomegaly 15
sleepiness 15
anesthesia 15
respiratory distress 15
shortness of breath 14
fever of unknown origin 13
pallor 13
myalgia 13
chills 12
ataxia 11
dizziness 11
lethargy 11
back pain 10
exertional dyspnea 10
motor symptom 10
night sweats 8
polyuria 7
cachexia 7
spasticity 7
asthenia 7
dystonia 6
apathy 6
syncope 6
enuresis 5
rigors 5
hypotonia 5
hemoptysis 5
paresthesia 4
paraparesis 4
angina 4
dysuria 4
paresis 4
overweight 4
dysarthria 4
low back pain 4
flushing 4
collapse 4
polydipsia 4
hemiplegia 4
insomnia 3
epigastric pain 3
agitation 3
starvation 3
myoclonus 3
decreased appetite 3
nasal congestion 3
dry skin 3
spasm 3
hoarseness 2
acute abdomen 2
abdominal discomfort 2
dark urine 2
polymyalgia 2
stridor 2
numbness 2
rhinorrhea 2
tinnitus 2
lightheadedness 2
consciousness disturbance 2
distraction 2
leg edema 2
ophthalmoplegia 2
hip pain 2
hypoproteinemia 2
right upper quadrant pain 2
hypothermia 2
leg pain 2
colic 2
sore throat 2
pachyonychia 2
vertigo 2
Hyperekplexia 1
atypical chest pain 1
twitching 1
incoordination 1
skin damage 1
personality change 1
functional recovery 1
thinning 1
autodigestion 1
Sedation 1
diminished hearing 1
forgetfulness 1
hangover 1
ACHE 1
cerebellar ataxia 1
thigh pain 1
neck pain 1
skin irritation 1
eds 1
non-productive cough 1
muscle cramps 1
orthopnea 1
alexithymia 1
Gastrointestinal symptoms 1
physical appearance 1
No adverse effect 1
limb pain 1
tense 1
lassitude 1
drooling 1
intestinal bleeding 1
torticollis 1
ENT symptoms 1
swollen penis 1
Neurologic symptoms 1
Spotting 1
acute stress 1
emaciation 1
productive cough 1
acidity 1
abdominal fullness 1
Rest tremor 1
bradypnea 1
Stepping 1
abnormal gait 1
memory loss 1
HSA 1
Mills 1
regurgitation 1
tingling 1
stuffy nose 1
analgesia 1
heartburn 1
hypertonia 1
muscle rigidity 1
masculinization 1
shoulder pain 1
livedo 1
Drug
MDS 2225
CSF 279
G-CSF 192
Lenalidomide 164
Dermatol 121
Deferasirox 39
MRC 37
lysine 33
Azacytidine 30
TEL 30
Fludarabine 27
AraC 27
Amifostine 25
Leaf 24
IL-2 24
Posaconazole 21
anti-CD33 21
TRM 20
Revlimid 19
Clofarabine 19
ROS 17
CTX 17
Dacogen 16
Arsenic trioxide 14
TTC 14
IFN-gamma 14
Cardiovasc 14
ROC 12
ARA-C 11
Etoposide 11
Epoetin 10
Rituximab 9
Vitamin K2 9
Bortezomib 9
Imatinib 9
Campath 9
Tipifarnib 9
Campath 9
ascorbate 8
Tacrolimus 8
Prednisolone 8
Filgrastim 8
Spectrum 8
Antithymocyte globulin 8
Filgrastim 7
Infliximab 7
Ethyol 7
Gleevec 7
Glutathione 7
Idarubicin 7
Infliximab 7
ETS 6
Erlotinib 6
Fluconazole 6
LCM 6
Epoetin alfa 6
LCM 6
ENT 5
Lonafarnib 5
CTX 5
TMS 5
Epoetin alfa 5
DBS 5
Prednisone 5
IL-11 5
NBT 5
CTX 5
Monit 5
Dial 4
Heme 4
Mutagen 4
BLM 4
Bexxar 4
Spectrum 4
Darbepoetin alfa 4
Zevalin 4
ALA 4
p75 4
Midostaurin 4
Adriamycin 4
AZT 4
AZT 4
vitamin E 4
Posture 3
Zebularine 3
Retinoic acid 3
EE2 3
CCL 3
G418 3
Vorinostat 3
Sorafenib 3
-deoxyadenosine 3
Bayer 3
SBT 3
Gel 3
Fraction 3
Vitamin B12 3
CTC 3
THF 3
CPZ 3
VCR 3
Vitamin B 3
CTC 3
Vitamin K 3
ABC 2
Itraconazole 2
Bestatin 2
Activin 2
Dasatinib 2
Asn 2
Atropine 2
Palmitoyl 2
Ranitidine 2
Retinoic Acid 2
Serum albumin 2
Rasagiline 2
DNase I 2
Micafungin 2
IFN-beta 2
Tandutinib 2
Silica 2
TAT 2
AmBisome 2
Ambisome 2
Paraffin 2
niacin 2
Camp 2
Lenograstim 2
Sodium valproate 2
citric acid 2
Vitamin A 2
MDM 2
PTC 2
Eculizumab 2
CPT-11 2
EML 2
Caspofungin 2
Frontal 2
Asthma 2
Diphenhydramine 2
NAG 1
Triad 1
NADH 1
CDX 1
Coral 1
Cidofovir 1
caffeine 1
Trimethoprim-sulfamethoxazole 1
THA 1
Acyclovir 1
Leucovorin 1
Nelarabine 1
Ranibizumab 1
Forodesine 1
Biopolymers 1
Gelatin 1
Rocaltrol 1
AMC 1
FCV 1
Anidulafungin 1
more...
Enzyme
ERK 311
focal adhesion kinase 266
peroxidase 144
topoisomerase 126
DNA methyltransferase 126
topoisomerase 117
BMT 107
CD13 98
mitogen-activated protein kinase 63
reverse transcriptase 59
lactate dehydrogenase 51
alkaline phosphatase 51
protein kinase 46
caspase-3 45
lysozyme 39
CD10 37
proteasome 32
P-glycoprotein 30
farnesyltransferase 23
farnesyltransferase 23
tryptase 21
phosphoglycerate kinase 21
trypsin 21
RNA polymerase 20
STR 18
neutrophil elastase 18
NOS 18
TdT 16
isocitrate dehydrogenase 16
alanine aminotransferase 16
NQO1 15
glutathione S-transferase 15
isocitrate dehydrogenase 15
MDR 14
MEK 14
thrombin 13
phospholipase C 13
granzyme B 13
thyroid peroxidase 13
aspartate aminotransferase 12
calcineurin 12
PARP 12
protein kinase C 12
demethylase 12
ribonucleotide reductase 11
luciferase 11
ribonucleotide reductase 11
APC 11
transcriptase 11
cytidine deaminase 10
phosphatidylinositol 3-kinase 9
ACE 9
caspase-1 8
aldehyde dehydrogenase 8
ferrochelatase 8
endonuclease 8
elastase 7
DNA polymerase 7
glucose-6-phosphate dehydrogenase 7
AMP-activated protein kinase 7
histone acetyltransferase 7
caspase-8 7
ATPase 6
asparaginase 6
AMPK 6
NADPH oxidase 6
creatine kinase 6
PI-PLC 6
ALA synthase 6
caspase-9 6
acid phosphatase 6
gamma-glutamyl transpeptidase 6
catalase 6
hypoxanthine-guanine phosphoribosyltransferase 6
glyceraldehyde-3-phosphate dehydrogenase 5
GSK 5
AMPK 5
NADPH oxidase 5
plasmin 5
thymidine kinase 5
acetylcholinesterase 5
ricin 5
histone demethylase 5
ceruloplasmin 5
adenosine deaminase 4
aldehyde dehydrogenase 4
matrix metalloproteinase 9 4
IKK 4
cdc2 4
carboxylesterase 4
protein phosphatase 2A 4
CYP3A4 4
deoxycytidine kinase 4
MTD 4
polo-like kinase 1 4
adenosine deaminase 4
aldehyde dehydrogenase 3
TGT 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
CDH 3
ornithine decarboxylase 3
thromboplastin 3
cholinesterase 3
thymidylate synthase 3
phosphodiesterase 3
deoxyguanosine kinase 3
beta-glucuronidase 3
dihydrofolate reductase 3
DAT 3
phosphoinositide 3-kinase 3
purine nucleoside phosphorylase 2
DNA ligase 2
DNA ligase 2
CAD 2
CAD 2
BAL 2
MIP 2
PKG 2
cytochrome oxidase 2
indoleamine 2,3-dioxygenase 2
MCS 2
matrix metalloproteinase 2 2
glutathione reductase 2
monoamine oxidase 2
PFI 2
methionine synthase 2
separase 2
superoxide dismutase 2
RNase 2
deaminase 2
CAD 2
MPP 2
renin 2
RNase 2
pyruvate kinase 2
urokinase-type plasminogen activator 2
tyrosine hydroxylase 2
PST 2
methylenetetrahydrofolate reductase 2
beta-lactamase 2
peroxiredoxin 2
arginase 2
factor C 2
CPT 2
CPT 2
CPT 2
phospholipase D 2
methylenetetrahydrofolate reductase 2
TAT 2
LPL 2
AST 2
chitinase 2
Thy1 2
prostate-specific membrane antigen 2
iduronate-2-sulfatase 1
CFI 1
glyceraldehyde-3-phosphate dehydrogenase 1
aconitase 1
poly(A) polymerase 1
more...
Compound
DNA 1302
Clin 1046
Dec 1024
iron 458
retinoic acid 157
5-Azacytidine 144
Ara-C 144
oxygen 129
Ara-C 121
5-Aza-2'-deoxycytidine 96
His 89
water 69
BCR 63
benzene 63
tyrosine 62
DAC 56
TBI 52
acetate 50
ABL 49
Neo 48
creatinine 47
TNF 46
lysine 43
sodium 39
copper 38
calcium 36
zinc 32
VP-16 32
TEL 30
Hemoglobin 30
serine 27
iodine 25
Optimal 24
GTP 24
Amifostine 24
Cyclosporine 24
phosphate 24
DFS 23
ATP 23
MTT 23
pyrimidine 22
pyrimidine 22
vitamin D 21
PDQ 19
INT 19
Busulfan 19
glucose 19
ammonium 18
CPT 18
arginine 18
CTX 17
Benzene 17
Pac 16
ADP 16
nitrogen 15
cysteine 15
hydrogen 15
ITP 15
Hydroxyurea 14
Topotecan 14
MEK 14
DFO 14
ADP 14
Topotecan 14
ADP 14
methanol 14
ethanol 14
MDR 14
acetonitrile 14
PEG 13
dUTP 13
FK506 13
leucine 13
alanine 13
Phe 13
PEG 12
hydroxyglutarate 12
TEM 12
Asp 12
Methotrexate 12
methionine 11
urea 11
THP 11
THP 11
Valproic acid 11
PAC 11
GSH 11
GSH 11
bromide 10
salt 10
AMP 10
Amphotericin B 10
Danazol 10
MTX 10
silver 10
A 71 9
Menadione 9
PAS 9
threonine 9
DBA 9
TET 9
TET 9
BCNU 8
MDA 8
formic acid 8
formic acid 8
formic acid 8
formic acid 8
aspartic acid 8
Prednisolone 8
Homoharringtonine 8
formic acid 8
6-12 8
Valproic acid 8
formic acid 8
formic acid 8
formic acid 8
aspartic acid 8
aspartic acid 8
boron 8
aspartic acid 8
formic acid 8
formic acid 8
CTP 7
phosphorus 7
DHB 7
PMA 7
Prednisone 7
Daunorubicin 7
valine 7
potassium 7
Adriamycin 7
DIC 6
CES 6
TOF 6
Vitamin D3 6
sulfate 6
uridine 6
L-leucine 6
2-oxoglutarate 6
EDTA 6
A 42 6
Temozolomide 6
MIC 6
HPC 6
SET 6
Gly 6
CIT 6
HPC 6
Vitamin D3 6
PMA 6
BLM 6
homocysteine 6
Serine 5
Off 5
hydroquinone 5
proline 5
DDP 5
isocitrate 5
DBA 5
more...