Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
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Drug
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Target Concepts:
Gene/Protein
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Query: UMLS:C0026986 (
myelodysplastic syndrome
)
14,926
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The
myelodysplastic syndrome
(
MDS
) is an abnormal clonal proliferation disease resulting from disorder of hematopoietic stem cells/progenitor cells and is characterized by ineffective hematopoiesis and high risk of transforming into acute leukemia. The present experimental studies in gene, chromosome, cytokines and biochemical aspects may put the genetically models for clarifying the pathogenesis of
MDS
, help to early evaluation of disease prognosis and eventually develop the strategies of more effective prevention and treatment methods for
MDS
. In this article, the advances of chromosome, gene, cytokines and biochemical aspects in pathogenesis of
MDS
are summarized on basis of proceedings of
ASH
meeting in 2007 years.
...
PMID:[Progress of experimental study on myelodysplastic syndrome -- review]. 1954 17
A model
MDS
-2002A microwave digestion sample preparation system with auto control pressure in obturation was developed for the determination of microelements in clearing-up plant's
ash
and environment soil sample by ICP-AES. The authors discussed sample preparation result influenced by mixed acid system, scale of mixed acid dispensation, proportion between solid and liquid and time of microwave clearing. Excellent project was A2B1C2, work procedure 2 in microwave process. When the dispensation scale was 6 : 2 : 1 : 1 and mixed acid system was HNO3-HCl-HF-HClO4, the result was the best in 10 min of microwave clearing at highest power. The reagent was dried at constant temperature electric heating board, with its salinity being dissolved by aqua fortis. The method was validated through the soil (GBW07401) and plant (GBW07603) for national standard matter. The relative error of its result is between 0.00% and 7.14%, and the relative standard deviation is between 0.87% and 5.25%. The method is quick, handy, saving reagent and completely digesting in dealing with plant's
ash
and soil sample, and the accuracy and precision of results are satisfying.
...
PMID:[Study of microelements in plant's ash and environmental soil by microwave digestion ICP-AES]. 1983 47