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Query: UMLS:C0026936 (Mycoplasma)
14,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mycoplasma spp. were isolated from the respiratory tissues of three buzzards. Bird I, a rough-legged buzzard (Buteo lagopus), showed airsacculitis, catarrhal-fibrinous pneumonia, and catarrhal tracheitis. Bird II, a common buzzard (Buteo buteo), revealed mycotic airsacculitis, bronchitis and pneumonia. Bird III was a healthy rough-legged buzzard. All isolates metabolized glucose but not arginine and were serologically identical by immunofluorescence and growth-inhibition tests. No serological cross-reactions were seen with several known Mycoplasma species.
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PMID:Isolation of a Mycoplasma sp. from three buzzards (Buteo spp.). 704 50

The efficacy of live Mycoplasma gallisepticum (MG) vaccine against respiratory mycoplasmosis was studied in three laboratory trials with commercial broilers. Broiler chickens were infected with the F or R strain of MG by eyedrop at 1 day of age, and challenged by aerosol exposure to the R strain of MG along with eyedrop vaccination against Newcastle disease and infectious bronchitis at 30 or 34 days of age. Observations were made of macroscopic lesions, severity of airsacculitis, isolations of MG, serologic test results, clinical signs, and mortality. In all the vaccinated groups, the air-sac-lesion score was lower after challenge than in unvaccinated control chickens. After challenge the control group also had a higher number of MG isolations from the air sac than did the vaccinated chickens. There were no air-sac lesions observed in broilers before challenge in 2 of 3 trials.
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PMID:Evaluation of a vaccine against Mycoplasma gallisepticum in commercial broilers. 727 43

During the 2-year period 1977 through 1979, 26 patients with Legionnaires' disease were seen at the Mayo Clinic and affiliated hospitals. The patients ranged in age from 17 to 81 years with a median of 51 years. Twelve (46%) were immunologically compromised. Most of the other patients had underlying chronic tobacco bronchitis. Hectic fever, cough, and diarrhea were common symptoms. Chest radiographs showed patchy perihilar infiltrates that often progressed to consolidation. Diagnosis was made by indirect fluorescent antibody testing in 15 patients (58%), but in no case was the test diagnostic during the first week of illness. In seven patients the diagnosis was established by positive direct flourescent antibody testing of lung tissue, in two cases by culture of lung tissue, and in one case each by direct fluorescent antibody positivity of sputum or bronchial washing. Of the 26 patients, 3 (12%) required hemodialysis for acute renal failure and 5 (19%) died. A favorable clinical response to therapy with erythromycin was noted. The differential diagnosis of Legionnaires' disease must include other bacterial pneumonias, as well as mycoplasma, psittacosis, Q fever, and viral pneumonia. For critically ill patients, open-lung biopsy may be necessary to provide a rapid diagnosis. Current evidence suggests that erythromycin alone or in combination with rifampin is the treatment of choice. A 3-week course of therapy is recommended in order to prevent relapse.
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PMID:Legionnaires' disease: a review of the epidemiology and clinical manifestations of a newly recognized infection. 735 52

Acute bronchitis is usually a viral infection which, unless there is a special disposition, does not require antibiotic therapy. For the initial oral chemotherapy of bacterial infections of the lower respiratory tract (chronic bronchitis, pneumonia) the effective and well tolerated cephalosporins, macrolides and amoxicillin plus beta-lactamase-inhibitor are recommended. In complicated cases with severe underlying disease, longer history or frequent exacerbations, quinolones should be given if Gram-negative infections are suspected or if initial therapy with other substances has failed. If Legionella, Mycoplasma or Chlamydia spp., so-called 'atypical' pathogens, are involved, macrolide antibiotics are the therapy of first choice. Special attention should be given to the increase in resistance against cotrimoxazole (trimethoprim-sulfamethoxazole) and tetracyclines. In hospitals where primary pneumonias are treated preferentially by intravenous medication, therapy should be switched to oral antibiotics as soon as feasible (follow-up therapy). For severely ill patients with secondary pneumonia and underlying disease, second generation cephalosporins with aminoglycosides, or monotherapy with third generation cephalosporins are recommended. In very severe, high-risk cases, third generation cephalosporins, combinations with high-dosage quinolones or ureidopenicillins plus beta-lactamase-inhibitors are suitable. Future development in the antibiotic treatment of respiratory infections will follow the current trend of lower dosages, with the clear objective of shortening treatment periods and achieving earlier discharge from hospital.
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PMID:A guide to the treatment of lower respiratory tract infections. 758 90

The pattern of distribution of bacteria, Mycoplasma pneumoniae and virus isolated from the same specimen recovered from the throat swab or the sputum of 479 patients with respiratory infections who were seen in six private clinics in Sendai City of Japan during the period from October to November in 1992 (period I) and from January to February in 1993 (period II) was documented. Of the 479 patients, 234 had acute pharyngitis, 145 had acute bronchitis, 96 had influenza, 21 had acute tonsillitis, 5 had acute pneumonia and 9 had other respiratory infections. One hundred (42.4%) strains of potential pathogen and one strain of M. pneumoniae were recovered from 236 cases in period I, and 66 (27.2%) strains of potential pathogen, one strain of M. pneumonae and 73 strains of Influenza virus (30.0%: 43 of type A Hong-Kong and 30 of type B) from 243 cases in period II. Of the 166 strains, major isolates were Staphylococcus aureus (56 strains), Streptococcus pneumoniae (12 strains), Streptococcus pyogenes (15 strains), Haemophilus influenzae (17 strains), Esherichia coli (4 strains), Klebsiella spp. (35 strains), Pseudomonas aeruginosa (4 strains) and Acinetobacter spp. (23 strains). Only one strain of S. aureus was resistant to methicillin (MIC: 50 micrograms/ml). None of S. pneumoniae was resistant to 1 microgram/ml of ampicillin. Ciprofloxacin was administered to 113 cases and roxythromycin to 220 cases by doctors in charge.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Studies on respiratory infections in primary care clinic (V). The pattern of distribution on bacteria, Mycoplasma pneumoniae and virus isolated from patients with respiratory infections, who were seen in six private clinics, and clinical efficacy of ciprofloxacin and roxithromycin]. 782 4

To gather information on backyard chicken flocks in Chitungwiza, an urban center in Zimbabwe, 85 flock owners were interviewed. The mean flock size was 53 birds (range 1-650), and most birds were kept for meat, for either domestic consumption or local sale. Mean age at slaughter was 12.4 weeks (range 8-24). None of the owners vaccinated their birds, and reported mortality rates were high (mean 25%), most commonly being associated with diseases causing eye and respiratory problems. Most owners complained of a lack of technical and veterinary advice. Commercial enzyme-linked immunosorbent assays on sera from 460 birds in 52 flocks showed that the birds had been exposed to avian reovirus (3%), avian leukosis virus (9%), avian encephalomyelitis virus (11%), Newcastle disease virus (27%), Mycoplasma gallisepticum and M. synoviae (33%), Pasteurella multocida (52%), infectious bursal disease virus (55%), reticuloendotheliosis virus (65%), and infectious bronchitis virus (86%). Parasite infections were detected only rarely.
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PMID:Diseases and management of backyard chicken flocks in Chitungwiza, Zimbabwe. 783 19

Horseradish peroxidase-conjugated goat anti-ostrich IgG was raised and used in commercial enzyme-linked immunosorbent assay kits to detect antibodies reactive with 11 poultry pathogens in sera from 149 ostriches from nine farms around Zimbabwe. Antibodies were detected to turkey rhinotracheitis virus (99%), Newcastle disease virus (23%), avian reovirus (19%), infectious bursal disease virus (15%), avian encephalomyelitis virus (15%), Mycoplasma gallisepticum and/or M. synoviae (11%), reticuloendotheliosis virus (10%), Salmonella enteritidis (8%), avian leukosis virus (3%), infectious bronchitis virus (2%), and Pasteurella multocida (< 1%). Although evidence of prior infection with turkey rhinotracheitis and newcastle disease virus was present on all farms tested, there was marked variation between farms in the prevalence of exposure to other poultry pathogens.
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PMID:A serosurvey using enzyme-linked immunosorbent assay for antibodies against poultry pathogens in ostriches (Struthio camelus) from Zimbabwe. 783 18

This study was undertaken to characterize the epidemiology and clinical presentation of infection with Chlamydia pneumoniae in a population composed primarily of middle-aged and older adults. Pharyngeal swabs and acute and convalescent phase sera were obtained from outpatients presenting with signs and symptoms of an acute respiratory infection. Sera were examined using the micro-immunofluorescence (MIF) test to detect antibody to Chlamydia pneumoniae and complement fixation tests to detect Mycoplasma pneumoniae, influenza A virus, influenza B virus, respiratory syncytial virus and adenovirus. Pharyngeal swab specimens were cultured for Chlamydia pneumoniae and tested for Chlamydia pneumoniae by the polymerase chain reaction (PCR). A total of 743 patients with a mean age of 40.5 +/- 16.1 years were enrolled in the study. Twenty-one patients were serologically positive for acute Chlamydia pneumoniae infection in the MIF test. PCR was positive in 15 of the 20 serologically positive patients tested. Acute Chlamydia pneumoniae infection was identified in 3% (2/76) of subjects with pneumonia, 5% (12/247) of those with bronchitis, 5% (3/61) of those with sinusitis only and 2% (2/103) of those with pharyngitis only. Of the 21 patients with Chlamydia pneumoniae infection, seven (mean age of 33 years) had an antibody pattern suggesting a primary infection while 14 (mean age of 54 years) had a reinfection pattern. Patients with reinfection had milder disease than those with primary infection. PCR testing in the current study confirms the previously proposed serologic criteria of acute Chlamydia pneumoniae infection.
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PMID:Respiratory infection with Chlamydia pneumoniae in middle-aged and older adult outpatients. 788 46

Lower respiratory tract infections--croup, tracheo-bronchitis, bronchiolitis and pneumonia--represent one of the major causes of pediatric consultation. They occur most frequently during the first years of life, are usually not recurrent and require hospitalization in less than 2% of the cases. They are associated in time with epidemics of respiratory virus and Mycoplasma pneumoniae infections, but the role of bacteria as primary infectious agents, or as causes of superinfection is significant.
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PMID:[Epidemiology of lower respiratory tract infections in children]. 793 88

Interaction between mixed live vaccine (Newcastle disease and infectious bronchitis), Mycoplasma gallisepticum (MG) and Escherichia coli (EC) was studied in specific-pathogen-free chickens, aged 7 days, inoculated intranasally. In the tracheas of chickens inoculated with vaccine, MG and EC, profuse multiplication of EC occurred together with severe and persisent histological lesions, and some birds died from EC infection. Similar though less dramatic effects occurred in birds that received vaccine and EC. The tracheas of chickens inoculated with the vaccine alone, or with MG and EC, or with MG alone, showed comparatively mild effects. There were no histological lesions in the tracheas of chickens inoculated with EC alone. This study suggests that the field use of mixed live vaccine in flocks infected with MG may induce EC septicaemia.
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PMID:Effect of mixed live vaccine (Newcastle disease and infectious bronchitis) and Mycoplasma gallisepticum on the chicken respiratory tract and on Escherichia coli infection. 796 25


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