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Query: UMLS:C0026936 (Mycoplasma)
 14,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The in vitro transformation of lymphocytes stimulated by a Mycoplasma pneumoniae preparation was measured by the uptake of 14C-thymidine. The lymphocytes from five patients with M.pneumoniae pneumonia showed a high degree of responsiveness when they were compared to the lymphocytes taken from eleven healthy control subjects who lacked M.pneumoniae antibodies. Another four patients with an acute affection of the central nervous system and serological evidence of an actual or recent M.pneumoniae infection had a lymphocyte response within the same range as that of the controls. The transformation of lymphocytes was studied at intervals for seven months after the onset of the illness in one of the patients with pneumonia. These studies showed an increasing response to a small dose of mycoplasma antigen. Lymphocyte transformation induced by other microbial antigens was studied in three pneumonia patients during and after convalescence. The first responses were low and increased more steeply than the response to M.pneumoniae. The later responses to the mycoplasmal and to the other microbial antigens increased in parallel. The usefulness of incorporating other microbial antigens in the evaluation of the patient's immune response to a relevant antigen in this type of experiment is discussed.
Infection 1976
PMID:Lymphocyte transformation studies in Mycoplasma pneumoniae infections. 95 97

Infection with Mycoplasma pneumoniae appears to follow a cyclic pattern in the United Kindom, with periods of increased prevalence lasting about two years. Outbreaks occurred in 1971-1972 and 1974-75, and probably also in 1967-68. Infection confirmed by laboratory tests appeared to be commonest in older children, especially those aged 5-14, and least common in adults over 65 years of age. Lower respiratory tract infection was the clinical feature most frequently reported.
Infection 1976
PMID:Epidemiology of Mycoplasma pneumoniae infection in the United Kingdom: an analysis of reports to the Public Health Laboratory Service of England and Wales. 95 98

The analysis of approximately 60,000 serum samples collected from patients with different clinical symptoms between 1965 and 1975 in Switzerland yielded positive reactions indicating a recent infection with Mycoplasma pneumoniae in 2-30% during this period. Among 1,555 patients with clinical symptoms of an acute respiratory infection, 359 patients or 23% had antibody titers indicating a recent infection with M.pneumoniae. On the basis of these results it is concluded that M.pneumoniae is the most frequent cause of acute infections of the respiratory tract.
Infection 1976
PMID:The laboratory diagnosis and epidemiology of Mycoplasma pneumoniae in Switzerland. 95 99

The epidemiological survey was carried out in a Calabrian population in order to ascertain the incidence of antibodies to Mycoplasma pneumoniae. In the past it has been felt that this infection does not occur in Southern Italy. We have found an incidence in our survey equal to that of the other countries. It was impossible to tell when these infections had occurred and the possibility of a continuing survey is discussed.
Infection 1976
PMID:The frequency of Mycoplasma pneumoniae antibodies in a Calabrian population. 95

An epidemiological survey was carried out at two centres in the north of England (Liverpool and Sunderland). One hundred and twenty patients were included in this survey to determine the relative incidence of Mycoplasma pneumoniae infections in patients who present to their physician with an acute lower respiratory tract infection. Data were available at the end of the survey in 115 patients. Only one patient had a positive test for M.pneumoniae. There were nine patients who had a positive antibody test for either influenza or para-influenza. Four patients had a positive test for respiratory syncytial viruses. This survey points out the problems in the clinical diagnosis of respiratory infections in general practice.
Infection 1976
PMID:A general practice survey of the incidence of Mycoplasma pneumoniae infections. 95 1

Seventeen cases of primary atypical pneumonia which were probably caused by Mycoplasma pneumoniae were studied as in-patients in hospital. All of these patients were treated with intravenous doxycycline and responded quickly to therapy. It has been shown that approximately 30-50% of the cases with primary atypical pneumonia are caused by M. pneumoniae. The remainder of the cases are caused by either viruses or possibly rickettsiae.
Infection 1976
PMID:The treatment of primary atypical pneumonia with intravenous doxycycline: a report of clinical observations. 95 2

A study was started in 1972 in order to determine the true etiology of patients who presented with obscure pulmonary infiltrates. Patients who were included in this study had sera drawn on two occasions. Complete testing was performed for the various viruses and also for Mycoplasma pneumoniae antibodies. The study continued through 1975 and a total of 159 patients were included. Of these 159 patients, 28 had positive complement fixation tests for M. pneumoniae antibodies. The clinical profile and treatment course is outlined and discussed.
Infection 1976
PMID:Hospital treatment and diagnosis of Mycoplasma pneumoniae pneumonia. 95 3

A comparative study was undertaken in order to ascertain the effects of a Mycoplasma pneumoniae infection on pulmonary function. It appears that the literature has many articles devoted to the clinical symptomatology of this type of infection but there is very little information available on the abnormalities which occur in the lungs with this infection. The patients who were used as a comparative model had lung lesions which gave a similar radiographic appearance. The significant finding was that an obstructive syndrome with increased airway resistance was noted in the M.pneumoniae pneumonia patients.
Infection 1976
PMID:The results of pulmonary function tests in patients infected with Mycoplasma pneumoniae. 95 6

A man with severe bilateral bronchopneumonia and a right lobar consolidation caused by Mycoplasma pneumoniae, had a concurrent myocarditis. The possible aetiology of the patchy pulmonary opacities is discussed. A literature review of cases of myocarditis associated with M.pneumoniae is presented.
Infection 1976
PMID:Myocarditis and severe bilateral bronchopneumonia caused by Mycoplasma pneumoniae. 95 5

Nine children between the ages of seven to 12 were studied. All of these children had an acute unilateral pneumonia caused by Mycoplasma pneumoniae. Regional pulmonary function studies were performed with the aid of an Xe133 radio-spirometry. It was shown with this technique that the ventilation of the infected part was more reduced than the perfusion during the acute stage. Fourteen to 22 days after the onset of the disease three children had normal chest X-rays but abnormalities of the pulmonary function tests. In one child this abnormal function persisted at the third follow-up some months later. By the use of regional pulmonary function studies subtle abnormalities can be observed which would normally be overlooked when examining the pulmonary function of both lungs.
Infection 1976
PMID:Pulmonary function in children with Mycoplasma pneumoniae pneumonia. 95 7


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