Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0026918 (Mycobacterium)
 52,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 23-year-old healthy man suffered a puncture wound from the fin of a catfish. Chronic tenosynovitis subsequently developed. Synovectomy was performed and cultures yielded Mycobacterium terrae. This organism, usually considered nonpathogenic, has only rarely been associated with human disease. This case further supports the role of this organism as a potential human pathogen and further suggests that M terrae should be considered in aquatic-associated hand tenosynovitis.
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PMID:Chronic tenosynovial hand infection from Mycobacterium terrae. 51 21

Mycobacterium kansasii musculoskeletal infections are unusual. The infection presents as either a tenosynovitis, monoarticular arthritis or generalized systemic spread. In 2 patients, vigorous surgical and antimycobacterial medical regimens controlled the infection and produced full return of function.
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PMID:Musculoskeletal infections due to Mycobacterium kansasii. 72 92

A 57-year-old female patient presented with a tenosynovitis due to Mycobacterium avium-intracellulare (MAI). A relapse occurred following surgical treatment, after which she was successfully treated with ansamycin and ethambutol. Previously reported cases of tenosynovitis due to MAI are reviewed and the treatment modalities are discussed.
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PMID:Tenosynovitis due to Mycobacterium avium-intracellulare: case report and a review of the literature. 148 22

Six cases of chronic tenosynovitis of the hand due to the Mycobacterium terrae complex were identified. All isolates from the six cases were identified as Mycobacterium nonchromogenicum by high-performance liquid chromatography and by testing for susceptibility to ofloxacin and to 5% NaCl. Ethambutol, sulfonamides (or trimethoprim-sulfamethoxazole), erythromycin, and streptomycin are the drugs most active against isolates of the M. terrae complex, and therapy with some combination of these agents plus surgical debridement offers the best current treatment of this disease. This study supports the contention arising from previous case reports of pulmonary disease that M. nonchromogenicum is the pathogenic member of the M. terrae complex.
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PMID:Chronic tenosynovitis of the hand due to Mycobacterium nonchromogenicum: use of high-performance liquid chromatography for identification of isolates. 196 98

Atypical mycobacteria causing extra-pulmonary disease in man are well documented. These infections are manifested by the presence of ulcers, abscesses and lymphadenitis. Mycobacterium marinum is particularly noted for infections involving the synovium, tendon sheaths, bursae and bone. Of lesser note is Mycobacterium terrae (radish bacillus), a nonchromogen also associated with tenosynovitis. We are not aware of any previous report of the association of M. terrae with synovitis in Australia. This case report describes a culture-proven case of tenosynovitis caused by M. terrae.
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PMID:Mycobacterium terrae tenosynovitis. 223 93

Once the most common form of chronic tenosynovitis of the hand, tenosynovitis due to Mycobacterium tuberculosis has become rare. Descriptions of this clinical entity can no longer be found in medical textbooks. Because of the rarity of this condition, diagnosis is frequently delayed. We present a case and review the presentation, diagnostic criteria, and treatment of tuberculous tenosynovitis. The relation of this infection to antecedent trauma and Dupuytren's contracture is discussed. M. tuberculosis should be considered in patients with chronic or recurrent tenosynovitis.
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PMID:Tenosynovitis of the hand: a forgotten manifestation of tuberculosis. 250 54

Granulomatous lesions of the skin and tendon sheaths after exposure to fish tank or aquarium water are frequently caused by non-tuberculous so-called atypical mycobacteria. Mycobacterium marinum is the species most often isolated from such lesions. Rarely, other non-tuberculous species of mycobacteria may be isolated. In contrast to swimming-pool granuloma as the epidemic form of Mycobacterium marinum infection of man, fish tank granuloma seems to be a rare sporadic human disease that is often misdiagnosed. We report eight cases of fish tank granuloma. Five patients had sporotrichoid lesions, and one patient had a singular lesion. Three patients presented with tenosynovitis. Culture-proven Mycobacterium marinum infection was found in four patients, in one patient the causative organism isolated from the biopsy specimen was identified as Mycobacterium kansasii. In three patients with typical appearance of the lesions and exposure to fish tank water, biopsy specimens for culture were not available, and the diagnosis was histopathologically confirmed. Surgical treatment had an unfavourable outcome in two of three patients. Conservative antimicrobial therapy was evaluated in six patients. Similar to published reports, the treatment with rifampicin in combination with other agents seemed to be a useful therapy. Complete remission was, however, also achieved with doxycycline monotherapy. Microbiological diagnosis should be attempted in suspected cases of fish tank granuloma, and, if therapy is indicated, we strongly suggest primary medical treatment.
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PMID:[Fish breeder granuloma: infection caused by Mycobacterium marinum and other atypical mycobacteria in the human. Analysis of 8 cases and review of the literature]. 253 60

Mycobacterium fortuitum infections in the hand and upper extremity are uncommon. Most previously reported cases have been secondary to trauma. A case of extensor tenosynovitis due to M fortuitum following treatment for a wrist ganglion is discussed here. The presentation, diagnosis, and treatment of M fortuitum infections are reviewed.
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PMID:Mycobacterium fortuitum infection following treatment of a ganglion cyst: case report and literature review. 281 64

Four culture-positive cases of flexor tenosynovitis of the hand caused by Mycobacterium marinum are reported. The organisms were cultured at 32 degrees. All patients were treated with a combination of flexor tenosynovectomy and antimycobacterial treatment with ethambutol and rifampin. The length of antimycobacterial treatment ranged from nine to 22 months. All four patients responded to treatment with cessation of signs of infection, increased range of motion, and complete wound healing.
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PMID:Mycobacterium marinum flexor tenosynovitis. 291 Jun 12

Mycobacterium marinum infections of the hand are very rare in the United Kingdom and we found only one case of involvement of deep structures (tenosynovitis) in the British literature. We report a case of septic arthritis due to the organism.
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PMID:Septic arthritis of the hand due to Mycobacterium marinum. 317 7


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