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Query: UMLS:C0026918 (Mycobacterium)
 52,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Counterimmunoelectrophoresis (CIE) was applied in the detection of antibodies to Mycobacterium johnei in 110 sheep, 11 goat and 31 cattle sera and compared to immunodiffusion (ID) test. One per cent Noble agar, 7 ml per slide of 5 cm x 10 cm; barbitone-tris buffer, mu = 0.03, pH 8.6; a constant current of 5 mA per slide and M johnei protoplasmic antigen at 4 mg per ml were found to impart high sensitivity to CIE and give rapid results. CIE detected 97 sheep, 11 goat and 31 cattle positive sera, a total of 139, as compared to 44, 11, 28 and 83 respectively, detected by ID. Strongly positive sera could be demonstrated within 30 minutes by CIE and the test was run for only 90 minutes while earliest reactions were not observed before 18 hours and some reactions took 144 hours to develop in ID test.
Vet Rec 1978 May 06
PMID:Detection of antibodies to Mycobacterium johnei by counterimmunoelectrophoresis. 9 79

Specimens of lung, liver and mesenteric lymph node from cows and buffaloes slaughtered in the Lahore area were cultured to investigate the type of mycobacteria involved in bovine tuberculosis. Employing the concentration method, 56 out of 530 cattle were found to be culture positive for acid-fast bacteria, 48 being Mycobacterium bovis and eight atypical mycobacteria. No M tuberculosis or M avium was isolated. Most of the isolated M bovis strains were found to be highly virulent for rabbits.
Vet Rec 1979 May 26
PMID:Isolation and identification of mycobacteria from cattle slaughtered in Pakistan. 38 8

The prevalence of antibodies to Mycobacterium johnei in pre-colostral lambs in a flock of sheep infected with Johne's disease was investigated. Blood from 134 ewes and their 143 lambs were collected immediately after lambing. Double immunodiffusion and counterimmunoelectrophoresis tests were used to detect antibodies to M johnei. Four (3 per cent) of 135 lambs born to 127 ewes with serological evidence of exposure to M johnei had detectable antibodies in their sera. All lambs fed colostrum from serologically positive ewes had serum antibodies.
Vet Rec 1979 Jul 07
PMID:The prevalence of antibodies to Mycobacterium johnei in colostrum deprived lambs. 55 5

The gross and histological appearances of the lesions of tuberculosis in 36 wild badgers found to be infected with Mycobacterium bovis are described. These badgers were examined over a period of two years during an investigation into the possible epidemiological association of tuberculosis in badgers and cattle. The possible significance of the lesions in transmission of M bovis to cattle and other badgers is discussed. The histological appearance of the lesions was considered to be indicative of a lesser hypersensitivity reaction than is seen in the bovine.
Vet Rec 1976 Jan 03
PMID:Tuberculosis in wild badgers (Meles meles) in Gloucestershire: pathology. 76 93

Sera from 775 adult milking cattle on 13 farms in Friesland and from 359 of the same cattle taken during the following year, were examined for evidence of infection with M johnei by the complement fixation, fluorescent antibody, haemagglutination, haemagglutination-lysis and immunodiffusion tests. Eighteen animals, not clinically affected but which had serologically positive tests were slaughtered and M johnei was isolated in cultures from 16. The fluorescent antibody test was as sensitive as the complement fixation test. The other tests were relatively insensitive and would only be of value as confirmatory tests in the presence of reactions to the first two tests. It is concluded that the use of the fluorescent antibody and the complement fixation test together was of value in detecting sub-clinical Mycobacterium johnei infection.
Vet Rec 1976 Jun 05
PMID:Diagnosis of Johne's disease in cattle: a comparison of five serological tests under field conditions. 82 56

Mycobacterium bovis was isolated from the respiratory tracts of three cattle which registered negative to tuberculin testing; no tuberculous lesions were found and the culture of lymph nodes and other tissues proved negative. One animal was from a group of five calves which had been inoculated intranasally with M bovis, and the organism was recovered once only from nasal mucus sampled 100 days after inoculation. The second animal had had contact with experimentally infected cattle which were excreting M bovis and the third was from a commercial farm. The results of ELISAS for antimycobacterial antibodies and interferon-gamma, and of lymphocyte transformation assays are presented. The animals' immune responses provided evidence that each of them had been challenged.
Vet Rec 1992 Jul 18
PMID:Isolation of Mycobacterium bovis from the respiratory tracts of skin test-negative cattle. 144 Nov 61

An outbreak of tuberculosis in pigs and cattle caused by Mycobacterium africanum produced lesions in the pigs similar to those caused by M tuberculosis, M bovis and M avium, with caseation in the lymph nodes of the head and in the jejunal lymph nodes. Bacteriological examination of the dysgonic mycobacteria isolated showed that they were M africanum I. The intradermal tuberculin test was very reliable in pigs, differentiating between mammalian and avian reactions, and the results of the test were in accordance with the lesions found at meat inspection. No clinical signs were observed during the outbreak, and the infection was neither serious nor progressive. There were no lesions in the tuberculin-positive cattle. The source of the infection remains unknown.
Vet Rec 1992 Jul 18
PMID:An outbreak of tuberculosis in pigs and cattle caused by Mycobacterium africanum. 144 Nov 62

In recent years tuberculosis in deer caused by Mycobacterium bovis has become a disease of economic as well as public health importance to the deer farming industries of several countries, in particular those in Denmark, New Zealand and the United Kingdom. This paper sets the disease in a historical context and reviews current knowledge about various aspects of the condition, with particular reference to diagnosis and control and to research requirements for the future.
Vet Rec 1991 Jul 06
PMID:Tuberculosis in deer: a review. 189 11

Five of a group of six calves were inoculated with Mycobacterium bovis. Two more uninoculated calves were introduced to the group 84 days later. All the inoculated calves were subsequently shown to be excreting M bovis in nasal mucus. The uninoculated calf in the initial group of six became infected and subsequently excreted M bovis. The two uninoculated calves which were introduced later did not become infected. It was concluded that contact with nasal mucus from the infected cattle resulted in infection of the uninoculated calf and that the density of accommodation of animals excreting M bovis was an important factor in transmission of the disease.
Vet Rec 1989 Mar 18
PMID:Transmission of tuberculosis from experimentally infected cattle to in-contact calves. 265 75

An outbreak of tuberculosis due to Mycobacterium bovis in farmed red deer imported from an eastern European country is described. Twenty-six of the 106 deer examined at autopsy were found to be infected and 19 had visible lesions of tuberculosis. Single comparative intradermal tuberculin tests on 51 deer showed that the test had a specificity of 61.3 per cent and a sensitivity of 80 per cent relative to subsequent biological and cultural tests on tissues taken at autopsy. Three hundred and seventy eight culled fallow and sika deer which had been running in a park in contact with some of the infected animals were found to be free of tuberculosis.
Vet Rec 1988 May 21
PMID:Tuberculosis in imported red deer (Cervus elaphus). 304 88


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