Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0026916 (MAC)
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Human Gene/Protein
RAP140 12.6
glucosamine-6-phosphate deaminase 1 12.6
MPHOSPH8 12.6
MAC 12.5
RASGRP4 11.6
zinc finger RNA binding protein 11.0
hCD 10.6
CUB and Sushi multiple domains 1 10.3
PPHLN1 10.3
ZNF676 10.3
SYNC 9.8
GPNMB protein 9.6
RIC 9.3
MAC-1 9.3
Inhibitory PAS domain protein 9.1
SLC43A1 9.1
fatty acid desaturase 3 9.1
DBPA 9.0
HLA-DR beta-chain 9.0
acyl-CoA synthetase short-chain family member 2 8.9
TRIM34 8.9
MDP1 8.9
SLC38A9 8.8
E74-like factor 5 8.6
interferon gamma receptor 1 8.6
ccr6 8.6
activation-induced C-type lectin 8.4
EIF2A 8.4
SLC36A1 8.4
TAO2 8.3
ACK 8.3
SLC38A2 8.0
MORC2 8.0
collagen type I alpha 2 8.0
OGFOD1 8.0
alphaS1-casein 7.7
PGAM1 7.6
MAI 7.5
ANGPTL2 7.5
HPCL 7.5
more...
Disease
Extreme drug resistant tuberculosis 12.6
MAC 12.6
MAC bacteremia 12.3
Chronic active viral hepatitis 11.6
grade II angiocentric immunoproliferative lesions 11.6
Asymmetrical growth retardation 11.6
Mycobacterium avium complex lymphadenitis 10.6
Disseminated mycobacteriosis 10.6
Avian tuberculosis 10.4
Euthyroid goiter 9.6
Mycobacterium abscessus infection 9.5
Chronic empyema 9.4
Olecranon bursitis 9.4
Progressive outer retinal necrosis 9.3
Cytomegalovirus encephalitis 9.3
Other infectious diseases 9.0
jungle yellow fever 8.9
Acute and chronic pancreatitis 8.9
Tuberculosis verrucosa cutis 8.8
Substance-related disorders 8.8
Bronchial wall thickening 8.6
La Crosse encephalitis 8.4
Immune reconstitution syndrome 8.3
Myelokathexis 8.3
Enzootic bovine leukosis 8.3
AIDS cholangiopathy 8.2
Mild depression 8.1
bacterial colitis 8.1
Mycobacterium kansasii infection 8.1
atypical mycobacterial infection 8.1
Cervical lymphadenitis 7.9
Mycobacterium fortuitum infection 7.9
Chronic necrotizing pulmonary aspergillosis 7.9
congenital amegakaryocytic thrombocytopenia 7.8
DMAC 7.8
Granulomatous hepatitis 7.7
aregenerative anemia 7.7
Tumor morphology 7.7
Bone marrow toxicity 7.7
viral cardiomyopathy 7.7
more...
Symptom
Glossopharyngeal breathing 9.6
skin impairment 8.1
hypocapnia 6.2
night sweats 6.2
productive cough 6.1
Overlying 6.1
sinus pressure 5.5
adenitis 5.4
anesthesia 5.4
fever of unknown origin 4.7
aphonia 4.6
hypercapnia 4.6
Postoperative nausea and vomiting 4.5
breath holding 4.4
persistent cough 4.3
hemoptysis 4.3
No adverse effect 4.2
hopelessness 4.2
prostration 4.0
cough 4.0
fasciculation 3.8
exertional dyspnea 3.6
twitching 3.6
cachexia 3.6
muscle rigidity 3.5
Postoperative pain 3.5
clumsiness 3.5
retching 3.5
personality change 3.5
excessive sweating 3.4
Gastrointestinal symptoms 3.4
pleuritic chest pain 3.4
hoarseness 3.4
arthralgia 3.3
anorexia 3.3
neck stiffness 3.3
chills 3.3
asynergy 3.2
right upper quadrant pain 3.2
clonus 3.0
more...
Drug
Doxacurium chloride 11.0
Frova 9.8
Sodasorb 9.4
Fluroxene 9.3
SPFX 9.2
LVFX 8.7
Flurothyl 8.6
Zithromax 8.6
RBT 8.6
Frovatriptan 8.4
Fosamprenavir 8.3
CPFX 8.3
OFLX 8.2
Rifalazil 8.0
Tepoxalin 7.9
Dopexamine hydrochloride 7.4
CPFX 7.4
Norcuron 7.1
Azithromycin 7.0
Innovar 6.8
Sitafloxacin 6.6
RFP 6.6
Medetomidine 6.5
Hakka 6.3
Acetic Acid 6.2
Etravirine 6.1
Compound 19 6.1
Gatifloxacin 6.0
AMK 6.0
Doxapram 5.9
Crixivan 5.9
Crixivan 5.9
Hydroxyethylstarch 5.9
Crixivan 5.7
Tuberculin 5.7
Fentanyl 5.7
Eculizumab 5.7
TRM 5.6
EMB 5.5
Enoximone 5.5
more...
Enzyme
MSAS 6.7
organomercurial lyase 6.4
AAE 5.8
penicillopepsin 5.6
prolinase 5.4
jararhagin 5.3
lanosterol 14alpha-demethylase 5.2
MTD 4.9
alanyl-tRNA synthetase 4.8
SCP 4.8
BIS 4.7
lysostaphin 4.7
formaldehyde dehydrogenase 4.7
PCP 4.4
LuxS 4.4
glycerophosphate acyltransferase 4.3
proteinase-3 4.2
caspase-4 4.1
dextranase 3.9
ACC synthase 3.9
HCS 3.9
caspase-4 3.9
MAP 3.8
CGT 3.8
factor D 3.8
p100 3.8
STK11 3.7
NADH-cytochrome b5 reductase 3.5
dihydropteroate synthase 3.5
thiopurine methyltransferase 3.5
MDR 3.5
arylsulfatase 3.3
cellulose synthase 3.3
dihydrofolate reductase 3.2
CPM 3.2
argininosuccinate synthetase 3.1
E-2 3.1
alanine aminopeptidase 3.1
DAT 3.1
NQO1 3.0
more...
Compound
C9H14O3 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
D-Ribulose 1,5-bisphosphate 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C9H14O3 11.0
C10H16O2 11.0
C9H14O3 11.0
C9H14O3 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C10H16O2 11.0
C9H14O3 11.0
C10H16O2 11.0
C9H14O3 11.0
more...