UMLS:C0026850 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C0026850 (muscular dystrophy)
5,870 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)

.

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
dystrophin	1033
Mol	479
DAG	395
Sep	382
creatine kinase	340
merosin	249
dystrophin gene	211
glycoprotein	198
X-linked	169
Walker	165
DMD	144
dysferlin	141
utrophin	139
collagen	136
Dystrophin	128
DM1	127
Fukuyama-type congenital muscular dystrophy	114
cardiac muscle	105
Facioscapulohumeral muscular dystrophy	100
MRI	96
fukutin-related protein	85
LAMA2	79
Emery-Dreifuss muscular dystrophy	79
LMNA	77
fukutin	76
plectin	72
BMD	70
myostatin	69
DMPK	66
desmin	59
X-linked recessive	58
Laminin	58
lamin A/C	57
myosin	56
LARGE	56
dominant)	54
delta-sarcoglycan	52
dystrophin-associated glycoprotein	51
insulin	50
titin	49
EMD	49
gamma-sarcoglycan	48
glycosyltransferase	48
ATP	48
POMT1	48
ADL	47
calpain	44
caveolin-3	44
lamin A	44
ATPase	43
She	43
calpain 3	42
MyoD	42
membrane protein	41
DM2	41
myosin heavy chain	39
POMGnT1	37
endoplasmic reticulum	37
muscle protein	37
DUX4	36
POMT2	36
sarcomeric	34
ubiquitin	33
proteasome	31
acetylcholinesterase	31
glutathione peroxidase	29
neuronal nitric oxide synthase	29
LGMD2A	28
myoglobin	28
myogenin	28
agrin	27
cytoskeletal protein	27
UTR	27
CCTG	27
CPK	27
extracellular matrix protein	25
sarcospan	25
caveolin	24
nitric oxide synthase	23
PLEC1	22

Disease
muscular dystrophy	5870
Duchenne muscular dystrophy	1067
myopathy	592
limb-girdle muscular dystrophy	363
DM1	332
muscular atrophy	320
cardiomyopathy	277
BMD	267
wasting	140
dilated cardiomyopathy	130
cancer	127
heart failure	123
FMD	110
amyotrophic lateral sclerosis	102
polymyositis	100
respiratory failure	97
mental retardation	90
lissencephaly	88
mental retardation	87
Fukuyama congenital muscular dystrophy	83
Emery-Dreifuss muscular dystrophy	81
Best	73
epidermolysis bullosa	73
diabetes	72
scoliosis	65
neuromuscular disorder	59
dysplasia	58
epilepsy	57
hydrocephalus	56
CMD	53
CMD	53
MDC1A	51
Ullrich	50
lipodystrophy	50
cerebral palsy	47
cystic fibrosis	47
myasthenia gravis	45
dysphagia	44
myositis	42
stroke	41
neuropathy	41
heart disease	39
tumor	39
Alzheimer's disease	39
congestive heart failure	37
progeria	35
DM2	35
hypertrophic cardiomyopathy	35
dermatomyositis	35
malignant hyperthermia	34
multiple sclerosis	34
prolapse	33
Charcot-Marie-Tooth disease	32
Parkinson's disease	31
Huntington's disease	31
cataract	31
genetic disorder	30
developmental delay	29
obesity	29
Congenital muscular dystrophy	29
LGMD2A	27
depression	27
AMD	27
peripheral neuropathy	26
malnutrition	26
haemophilia	25
cognitive impairment	25
ischemia	23
polio	23
myocardial infarction	23
atherosclerosis	22
Evans	22
IBM	21
GSH	21
Syndrome	20
neurological disease	20
severe mental retardation	20
autism	20
Down syndrome	19
osteoporosis	19

Symptom
weakness	733
hypotonia	131
anesthesia	75
fatigue	61
seizures	40
pain	32
cachexia	28
ataxia	19
myalgia	18
hypercapnia	17
ophthalmoplegia	15
exhaustion	14
dystonia	13
dyspnea	13
cough	12
muscle stiffness	11
collapse	11
respiratory distress	11
sleepiness	10
cerebellar ataxia	8
regurgitation	8
thinning	8
paresis	8
spasticity	8
starvation	7
discomfort	7
syncope	7
discomfort	7
constipation	6
analgesia	6
headache	6
abnormal gait	6
tremor	6
asthenia	6
twitching	5
hepatomegaly	5
torticollis	5
spasm	5
back pain	5
vomiting	5
muscle cramps	4
diarrhea	4
chest pain	4
tachypnea	4
paraparesis	3
abdominal pain	3
agitation	3
nausea	3
functional recovery	3
overweight	3
exertional dyspnea	3
angina	3
fasciculation	3
hypersomnia	3
Fatigability	3
snoring	3
dysarthria	3
muscle rigidity	3
orthopnea	2
apathy	2
chorea	2
low back pain	2
shortness of breath	2
abiotrophy	2
hemiplegia	2
growing pains	2
stridor	2
benign congenital hypotonia	2
memory loss	2
rundown	2
insomnia	2
sciatica	2
hypertonia	2
distraction	2
respiratory problem	1
rigors	1
giddiness	1
giddiness	1
Joint hypermobility	1
limb pain	1

Enzyme
creatine kinase	392
calpain 3	74
protein kinase	48
ATPase	45
calpain 3	37
proteasome	33
acetylcholinesterase	31
glutathione peroxidase	30
lactate dehydrogenase	25
mitogen-activated protein kinase	25
superoxide dismutase	24
aspartate aminotransferase	23
aldolase	23
N-acetylglucosaminyltransferase	20
alkaline phosphatase	19
alanine aminotransferase	18
catalase	16
cholinesterase	16
ERK	13
luciferase	12
beta-galactosidase	11
choline kinase	11
cathepsin B	11
phosphodiesterase	10
phospholipase A2	10
reverse transcriptase	9
trypsin	9
glycerol kinase	9
NOS	9
focal adhesion kinase	8
NO synthase	8
acid phosphatase	8
adenylate kinase	8
renin	8
RNase	7
phospholipase C	7
RNase	7
AST	7
ACE	7
m-calpain	6
transcriptase	6
ACS	6
pyruvate kinase	6
calcineurin	6
RNA polymerase	6
succinate dehydrogenase	6
phosphorylase	6
protein kinase C	6
glutathione reductase	5
caspase-3	5
AMP-activated protein kinase	5
citrate synthase	5
cytochrome oxidase	5
alpha-glucosidase	5
mu-calpain	4
Mg2+-ATPase	4
cathepsin D	4
myosin ATPase	4
complex I	4
NADPH oxidase	4
enolase	4
kallikrein	4
IKK	4
phosphofructokinase	4
peroxidase	4
collagenase	3
ribonuclease	3
5'-nucleotidase	3
LIS	3
ribonuclease	3
cathepsin C	3
papain	3
cathepsin L	3
carbonic anhydrase	3
aldose reductase	3
hyaluronidase	3
CPR	3
adenylate cyclase	3
arginase	3
ornithine transcarbamylase	3