Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0026850 (
muscular dystrophy
)
5,870
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
An elevation of
phosphoglycerate mutase
(PMG) has been detected in the blood plasma of the genetically dystrophic chicken and in Duchenne muscular dystrophy (DMD) patients. In the dystrophic chicken, plasma
PGM
in the pectoral muscle was simultaneously depressed to less than one-half that of the normal chicken. In a group of 9 DMD patients, plasma
PGM
activity was found to be significantly raised above the normal range. A survey of a small group of plasma specimens from human fetuses at risk for
muscular dystrophy
also suggested that
PGM
merits investigation as a potential adjunct to other diagnostic indices.
...
PMID:Plasma phosphoglycerate mutase as a marker of muscular dystrophy. 609 May 94
